Multilocular renal cyst having an entity of uncertain nature, is an uncommon benign lesion. As a treatment modality of renal multilocular cyst, simple or radical nephrectomy has been performed because of the difficulty in its accurate diagnosis and the documented association with malignancy. Herein, we report a case of renal multilocular cyst which was successfully treated by extirpation of the cystic mass only with preservation of the remaining normal renal parenchyma.
Diagnosis ; Nephrectomy

Nocturnal penile tumescence has been proposed as a source of objective data in the evaluation of erectile capacity and clinically important in differentiating between psychogenic and organic impotence. However, the absence of sleep information and difficult differentiation of movement artifact leads to false positive or false negative reaction when portable home monitor is used. This can be overcome by polysomnographic monitoring. In addition, sleep disorders affecting nocturnal penile tumescence also could be screened. Herein, we conducted a study to investigate the significance of polysomnographic nocturnal penile tumescence monitoring in 45 men with erectile dysfunction. The nocturnal penile tumescence data from polysomnographic method were compared with those from portable method, based on the results from standard method. The results obtained were summarized 1. Polysomnographic method showed higher sensitivity(82%), lower false positive(20%) and false negative rate(16%) than portable method (71%, 30%, 28%, respectively) in the differential diagnosis of impotence. 2. Among 10 patients, with measuring of air flow monitoring and anterior tibialis EMG one patient had periodic leg movement. 3. Statistically, parameters of total REM time, total tumescence time/total sleep time, number of maximum tumescence episodes, amount of maximum tumescence episodes, T-up and T-max phase in maximum tumescence episodes, circumferential changes in maximum tumescence episodes, and rigidity in maximum tumescence episodes were found to be significantly decreased in organic impotence group. These results reflect that polysomnographic NPTM provides more validity than portable NPTM on the outcome of the differential diagnosis of impotence, and it would contribute to screening of occult sleep disorders and to study for their characteristics in association with impotence.
Artifacts ; Diagnosis* ; Diagnosis, Differential ; Erectile Dysfunction* ; False Negative Reactions ; Humans ; Leg ; Male ; Mass Screening ; Penile Erection* ; Sleep Wake Disorders

PURPOSE: To realistically map the electric fields of biological tissues using a diffusion tensor magnetic resonance electrical impedance tomography (DT-MREIT) method to estimate tissue response during electrical stimulation. METHODS: Imaging experiments were performed using chunks of bovine muscle. Two silver wire electrodes were positioned inside the muscle tissue for electrical stimulation. Electric pulses were applied with a 100-V amplitude and 100-μs width using a voltage stimulator. During electrical stimulation, we collected DT-MREIT data from a 3T magnetic resonance imaging scanner. We adopted the projected current density method to calculate the electric field. Based on the relation between the water diffusion tensor and the conductivity tensor, we computed the position-dependent scale factor using the measured magnetic flux density data. Then, a final conductivity tensor map was reconstructed using the multiplication of the water diffusion tensor and the scale factor. RESULTS: The current density images from DT-MREIT data represent the internal current flows that exist not only in the electrodes but also in surrounding regions. The reconstructed electric filed map from our anisotropic conductivity tensor with the projected current density shows coverage that is more than 2 times as wide, and higher signals in both the electrodes and surrounding tissues, than the previous isotropic method owing to the consideration of tissue anisotropy. CONCLUSIONS: An electric field map obtained by an anisotropic reconstruction method showed different patterns from the results of the previous isotropic reconstruction method. Since accurate electric field mapping is important to correctly estimate the coverage of the electrical treatment, future studies should include more rigorous validations of the new method through in vivo and in situ experiments.
Anisotropy ; Diffusion Tensor Imaging ; Diffusion* ; Electric Conductivity* ; Electric Impedance ; Electric Stimulation* ; Electrodes ; Magnetic Resonance Imaging ; Methods ; Silver ; Water*

Coronary artery ectasia (CAE) is a rare condition defined as the dilatation of coronary artery to at least 1.5 times larger than the normal adjacent coronary artery. Clinical manifestations of CAE vary, ranging from asymptomatic to ST-segment elevation myocardial infarction (STEMI). Because of its rarity and clinical diversity, the best treatment strategy and prognosis for CAE remain unclear. We describe a case of STEMI caused by intracoronary thrombus formation within an ectatic area in a patient with liver cirrhosis (LC). The patient was successfully managed by thrombus aspiration only, without balloon angioplasty or stent implantation, and maintained by dual antiplatelet therapy with aspirin and ticagrelor, a potent new P2Y12 inhibitor.
Angioplasty, Balloon ; Aspirin ; Coronary Vessels* ; Dilatation ; Dilatation, Pathologic ; Humans ; Liver Cirrhosis* ; Liver* ; Myocardial Infarction* ; Platelet Aggregation Inhibitors ; Prognosis ; Stents ; Thrombosis*

Each diastereomer of 10-thiophenyl- and 10-benzenesulfonyl-dihydroartemisinin was synthesized from artemisinin in three steps, and screened against chloroquine-resistance and chloroquine-sensitive Plasmodium falciparum. Three of the four tested compounds were found to be effective. Especially, 10 beta-benzenesulfonyl-dihydroartemisinin showed stronger antimalarial activity than artemisinin.
Animals ; Antimalarials/chemistry/*pharmacology ; Artemisinins/chemistry/*pharmacology ; Chloroquine/pharmacology ; Drug Resistance ; Plasmodium falciparum/*drug effects ; Research Support, Non-U.S. Gov't

BACKGROUND: Even though paraquat-induced lung injury has been known as major cause of death after paraquat poisoning, survivors with lung injury after paraquat poisoning has been reported recently. The purpose of this study was to determine the long-term prognosis of paraquat-induced lung injury in survivors with prominent lung injury after paraquat poisoning. METHODS: The patients with prominent paraquat-induced lung injury after acute paraquat poisoning were followed up in this study. Biochemical data including hemoglobin, white blood cell count, arterial blood gas analysis, blood urea nitrogen, creatinine, aspartate aminotransferase, alanine aminotransferase, total bilirubin, amylase, lipase, and glucose, high resolution computed tomography (HRCT) and pulmonary function tests were followed up. RESULTS: The estimated amount of paraquat was 42.9 +/- 37.3 mL and follow-up duration was 3.6 +/- 2.1 years. The early HRCT findings of lung were ground glass opacities, consolidation, cystic changes and decrease of lung volume. The lung lesions were improved 11~20 months later, and these changes were continued to nearly normal findings. The early decrease in forced vital capacity was improved 8~12 months after paraquat poisoning and restored to normal range. CONCLUSION: In conclusion, paraquat-induced lung injury is not an irreversible and progressive change. Not only lung volume is increased, but also lung function is improved over time in long-term survivors after paraquat poisoning with prominent lung injury.
Alanine Transaminase ; Amylases ; Aspartate Aminotransferases ; Bilirubin ; Blood Gas Analysis ; Blood Urea Nitrogen ; Cause of Death ; Creatinine ; Follow-Up Studies ; Glass ; Glucose ; Humans ; Leukocyte Count ; Lipase ; Lung Injury* ; Lung* ; Paraquat ; Poisoning ; Prognosis* ; Reference Values ; Respiratory Function Tests ; Survivors ; Vital Capacity

PURPOSE: Although early treatment of neonatal necrotizing enterocolitis (NEC) is very important, there exists no definite way of diagnosing NEC at an early stage. Previous reports argue that gases in portal veins and liver parenchyme are detected by liver ultrasonography (USG) even when no symptoms corresponding to NEC are provoked. This study demonstrates the importance of liver USG for early diagnosis of NEC. METHODS: Abdominal USG was performed on 1381 newborn infants who were admitted to the neonatal intensive care unit of Soonchunhyang University Cheonan Hospital between February 2003 and September 2005. Twelve infants were diagnosed with NEC by liver USG and their individual pathologies were compared. RESULTS: All of the patients described here were full-term and the most frequent symptom observed was watery diarrhea; four had no symptoms at all. Severe metabolic acidosis was seen in two patients, a rise of C-reactive protein (CRP) in five patients and rotavirus antigen positivity in five patients. One of the patients showed portal vein gas, pneumatosis intestinalis and ileus in a simple abdominal radiography and another patient showed ileus only. However, all of the other 10 patients presented with no abnormal symptoms, according to simple abdominal radiography. CONCLUSION: NEC should be considered in neonates with gases present in portal veins, intestinal walls and liver parenchyme, as detected by liver USG even when no symptoms corresponding to NEC are provoked.
Acidosis ; C-Reactive Protein ; Chungcheongnam-do ; Diarrhea ; Early Diagnosis ; Enterocolitis, Necrotizing* ; Gases* ; Humans ; Ileus ; Infant ; Infant, Newborn* ; Intensive Care, Neonatal ; Liver* ; Pathology ; Portal Vein* ; Radiography, Abdominal ; Rotavirus ; Ultrasonography*

The influence of colchicine, colcemid, ginseng-alcohol extract, saponin, garlic alcohol-ether extract, and X-irradiation on free floating peritoneal mast cells were studied in rats by means of a phase contrast microscope. After the intraperitoneal injection of colchicine or colcemid the mast cells of the albino rat peritoneal fluid show an altered morphology. Ginseng-alcohol extract, allicin extracted from garlic, and X-irradiation do not elicit this cytological response.Mast cells exposed to saponin exhibit a severe destruction and degranulation. The relation of the mast cell-damaging agents, metabolic poisons, and X1-irradiation to the mast cell response is discussed with reference to the morphological changes. These are compared with the data of Padawer (1960, 1966).
Animals ; Colchicine/*pharmacology ; Mast Cells/*drug effects/*radiation effects ; Microscopy, Phase-Contrast ; *Panax ; Plant Extracts/pharmacology ; *Plants, Medicinal ; *Radiation Injuries, Experimental ; Rats ; Saponins/*pharmacology

No abstract available.
Animals ; Mice* ; Pancreas, Exocrine*