The International University of Health and Welfare School of Medicine accepts 20 international students every year. In this paper, we report on the practice of “Medical Japanese Class” for these international students. The “Medical Japanese Class” is a class in which students learn medical terminology through listening, speaking, reading, and writing activities, and make presentations in Japanese based on the knowledge they have learned in English. This is a combination of the Language for Specific Purposes model and the Sheltered model, of Content-Based Language Instruction. We designed and implemented a lesson in which Japanese instructors used medical materials to introduce medical terminology and expressions. Medical faculty checked the application and correctness of medical content.