Kounis syndrome (KS) is defined as acute coronary syndrome (ACS) induced by coronary vasospasm associated with an anaphylactic reaction. This condition was described in 1991 by Kounis, detailing potential pathophysiological pathways for coronary spasm. We report a case of Type 2 KS – a patient with stented coronary artery disease who presented with ST-elevation myocardial infarction (STEMI) following intramuscular Diclofenac Sodium.