1.A brief overview of cell therapy and its product.
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2013;39(5):201-202
No abstract available.
Tissue Therapy*
2.Mesenchymal stromal cells: new insight on their identity and potential role in cell therapy.
Korean Journal of Hematology 2010;45(4):219-221
No abstract available.
Tissue Therapy
3.Antibody Directed Cell Therapy in Pediatric AIDS.
Journal of the Korean Pediatric Society 1995;38(7):881-885
No abstract available.
Cell- and Tissue-Based Therapy*
4.The Past, Present, and Future of Adoptive T Cell Therapy.
Donghoon CHOI ; Tai Gyu KIM ; Young Chul SUNG
Immune Network 2012;12(4):139-147
Although adoptive T cell therapy (ACT) has become a promising immunotherapeutic regime for cancer treatment, its effectiveness has been hindered by several inherent shortcomings regarding safety and efficacy. During the past few decades, several strategies for enhancing the efficacy of ACT have been developed and introduced in clinic. This review will summarize not only the past approaches but also the latest strategies which have been shown to enhance the anticancer activity of ACT.
Immunotherapy
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Tissue Therapy
5.Cardiovascular repair with bone marrow-derived cells.
Woan Sang KIM ; Sangho LEE ; Young Sup YOON
Blood Research 2013;48(2):76-86
While bone marrow (BM)-derived cells have been comprehensively studied for their propitious pre-clinical results, clinical trials have shown controversial outcomes. Unlike previously acknowledged, more recent studies have now confirmed that humoral and paracrine effects are the key mechanisms for tissue regeneration and functional recovery, instead of transdifferentiation of BM-derived cells into cardiovascular tissues. The progression of the understanding of BM-derived cells has further led to exploring efficient methods to isolate and obtain, without mobilization, sufficient number of cell populations that would eventually have a higher therapeutic potential. As such, hematopoietic CD31+ cells, prevalent in both bone marrow and peripheral blood, have been discovered, in recent studies, to have angiogenic and vasculogenic activities and to show strong potential for therapeutic neovascularization in ischemic tissues. This article will discuss recent advancement on BM-derived cell therapy and the implication of newly discovered CD31+ cells.
Bone Marrow
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Regeneration
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Tissue Therapy
6.Cell-Based Therapy for Urinary Incontinence.
Korean Journal of Urology 2010;51(1):1-7
Urinary incontinence has become a societal problem that affects millions of people worldwide. Although numerous therapeutic modalities are available, none has been shown to be entirely satisfactory. Consequently, cell-based approaches using regenerative medicine technology have emerged as a potential solution that would provide a means of correcting anatomical deficiencies and restoring normal function. As such, numerous cell-based investigations have been performed to develop systems that are focused on addressing clinical needs. While most of these attempts remain in the experimental stages, several clinical trials are being designed or are in progress. This article provides an overview of the cell-based approaches that utilize various cell sources to develop effective treatment modalities for urinary incontinence.
Regenerative Medicine
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Tissue Therapy
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Urinary Incontinence
7.A Case of Cap Polyposis Treated by Conservative Management.
Kum Hei RYU ; Sung Ae JUNG ; Seong Eun KIM ; Hee Jung OH ; Ji Hyun SONG ; Hyun Joo SONG ; Hye Jung YEOM ; Tae Hun KIM ; Ki Nam SHIM ; Kwon YOO ; Il Hwan MOON ; Shi Nae LEE
Korean Journal of Gastrointestinal Endoscopy 2006;32(6):400-404
Cap polyposis is a rare intestinal disease that is characterized by the presence of inflammatory polyps consisting of elongated, tortuous and distended crypts that are covered by a 'cap' of granulation tissue. The pathogenesis and proper treatment of cap polyposis are still unclear. We experienced a case of cap polyposis, that was treated successfully by conservative management without the need for a pharmacotherapy or resection.
Drug Therapy
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Granulation Tissue
;
Intestinal Diseases
;
Polyps
8.A Case of Cap Polyposis Treated by Conservative Management.
Kum Hei RYU ; Sung Ae JUNG ; Seong Eun KIM ; Hee Jung OH ; Ji Hyun SONG ; Hyun Joo SONG ; Hye Jung YEOM ; Tae Hun KIM ; Ki Nam SHIM ; Kwon YOO ; Il Hwan MOON ; Shi Nae LEE
Korean Journal of Gastrointestinal Endoscopy 2006;32(6):400-404
Cap polyposis is a rare intestinal disease that is characterized by the presence of inflammatory polyps consisting of elongated, tortuous and distended crypts that are covered by a 'cap' of granulation tissue. The pathogenesis and proper treatment of cap polyposis are still unclear. We experienced a case of cap polyposis, that was treated successfully by conservative management without the need for a pharmacotherapy or resection.
Drug Therapy
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Granulation Tissue
;
Intestinal Diseases
;
Polyps
9.Precision Validation of Electromagnetic Physics in Geant4 Simulation for Proton Therapy.
So Hyun PARK ; Jeong Eun RAH ; Jung Wook SHIN ; Sungyong PARK ; Sei Chul YOON ; Won Gyun JUNG ; Tae Suk SUH
Korean Journal of Medical Physics 2009;20(4):225-234
Geant4 (GEometry ANd Tracking) provides various packages specialized in modeling electromagnetic interactions. The validation of Geant4 physics models is a significant issue for the applications of Geant4 based simulation in medical physics. The purpose of this study is to evaluate accuracy of Geant4 electromagnetic physics for proton therapy. The validation was performed both the Continuous slowing down approximation (CSDA) range and the stopping power. In each test, the reliability of the electromagnetic models in a selected group of materials was evaluated such as water, bone, adipose tissue and various atomic elements. Results of Geant4 simulation were compared with the National Institute of Standards and Technology (NIST) reference data. As results of comparison about water, bone and adipose tissue, average percent difference of CSDA range were presented 1.0%, 1.4% and 1.4%, respectively. Average percent difference of stopping power were presented 0.7%, 1.0% and 1.3%, respectively. The data were analyzed through the kolmogorov-smirnov Goodness-of-Fit statistical analysis test. All the results from electromagnetic models showed a good agreement with the reference data, where all the corresponding p-values are higher than the confidence level alpha=0.05 set.
Adipose Tissue
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Magnets
;
Proton Therapy
;
Protons
;
Water
10.The History, Principles, and Adverse Effects of Cryolipolysis.
Jae Beom PARK ; Chang Min KIM ; Seung Hyun CHUN ; Sang Wook SON ; Il Hwan KIM ; Hwa Jung RYU
Korean Journal of Dermatology 2016;54(5):325-328
Recently, various modalities for noninvasive reduction of adipose tissue, including cryolipolysis, radiofrequency, low-level laser therapy, and high-intensity focused ultrasound, have become available. Among these modalities, cryolipolysisis can selectively target certain tissues rich in lipids. Many preclinical and clinical studies have established the safety and efficacy of cryolipolysis for noninvasive body contouring. However, it can lead to serious adverse effects when performed by untrained clinicians. Thus, to promote the proper and safe use of cyolipolysis, we have summarized the history, basic principles, and adverse effects of cyolipolysis.
Adipose Tissue
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Low-Level Light Therapy
;
Ultrasonography