The authors analyzed 1867 donor eyes which were obtained from Central Eye Bank at St Mary's Hospital from Jan. 1977 to Aug. 1990. 1. 658 donors(68.7%) were female and 539(56.4%) were above 60 years of age. 2. The most common cause of death was circulatory disease(29.4%), followed by respiratory disease(20.4%) and tumor(13.7%) 3. In death to enucleation time, sixty-eight percent were below 6 hours and twelve percent were between 6 and 12 hours. 4. The most common source of donation was KOT DONG NAE(57.8%), followed by a charity institute(35.4%) and register(4.7%). 5. 982 eyes were used for research; of those, 520 eyes (52.9%) were used for research because of the cause of death.
Cause of Death ; Charities ; Eye Banks* ; Female ; Humans ; Tissue Donors*

I had an opportunity to visit U.S. Naval Tissue Bank and observed tissue procurement and preservation by freeze-drying method and its clinical application while I stayed in the Naval Hospital, Bethesda in 1954. The freeze-dried tissues, especially bone graft, has shown excellent bone repair experimentally and clinically. Recently the mechanisms of osteoinduction have observed by many researchers and isolated the substance, bone morphogenetic protein, and clarified the interaction between BMP and the determined or inducible osteoprogenitor cells.
Bone Morphogenetic Proteins ; Methods ; Tissue and Organ Procurement ; Tissue Banks ; Transplants

bone grafting has a broad range of applications and also limitations, thought it is the oldest and most important reconstructive techniques in the oral and maxillofacial surgical field. Further understanding of bone healing mechanism, bone physiology and bone biology, transplantation immunology, and development of tissue banking procedure has enabled oral and maxillofacial surgeons to reconstruct even the most difficult bony defects successfully with the preserved allogeneic bone implant. Now autogenous bone and allogeneic bone implants present a wide variety of surgical options to surgeons, whether used separately or in combination. The surgeons are able to make judicious and fruitful choices, only with a through knowledge of the above-mentioned biologic principles and skillful techniques. The author evaluated 116 cases where allogeneic bones were transplanted for oral and maxillofacial reconstruction.]]>
Allografts ; Biology ; Bone Transplantation ; Fruit ; Physiology ; Tissue Banks ; Transplantation Immunology

The maintenance of corneal endothelial cells is essential for success of corneal transplantation. Endothelial cell count by specular microscope and measurement of donor corneal thickness is useful in measuring the function of cornea. We studied difference of corneal thickness in central and peripheral corneal region in enucleated eye. We measured corneal thickness of 48 eyes(48 persons) with ultrasound pachymetry that were presented to The Eye Bank of Catholic University Medical College. Average age was 61.42+/-16.12 years and average time was 163.02+/-102.52 minutes until measurement of corneal thickness after death. Increased amount of corneal thickness was 136.73+/-101.44micrometer in center and 61.37+/135.46micrometer in periphery compared with normal average corneal thickness. According to these results, corneal edema due to functional loss of endothelial cells after death lead to increased corneal thickness, especially in central region being more statistically significant than peripheral region (p=0.002).
Cornea ; Corneal Edema ; Corneal Transplantation ; Endothelial Cells ; Eye Banks ; Humans ; Tissue Donors ; Ultrasonography

No abstract available.
Tissue Banks*

No abstract available.
Tissue Banks*

This study was performed to evaluate the effect of freeze-dried bone graft on space-making capacity and bone formation in the procedure of guided bone regeneration with titanium reinforced ePTFE membrane. After decortication in the calvaria, GBR procedure was performed on 8 rabbits with titanium reinforced ePTFE membrane filled with human FDBA(Rocky Mountain Tissue Bank, Aurora Co., USA). Decortication was performed to induce the effect of bone forming factor from bone marrow. The animals were sacrificed at 2 weeks, 4 weeks, 8 weeks and 12 weeks after the surgery. Non-decalcified specimens were processed for histologic analysis. The results of this study were as follows: 1. Titanium reinforced-ePTFE membrane was biocompatable and capable of maintaining the space-making. 2. FDBA particle was surrounded with connective tissues but there was no evidence on new bone formation. 3. FDBA particle resorbed continuously but it remained until 12weeks after the surgery. Within the above results, TR-ePTFE membrane could be used effectively for Guided bone regeneration but It was assumed that FDBA does not appear to contribute to bone formation.
Animals ; Bone Marrow ; Bone Regeneration ; Connective Tissue ; Humans ; Membranes ; Osteogenesis ; Rabbits ; Skull ; Tissue Banks ; Titanium ; Transplants*

bone loss was found. Therefore, surgical treatment was performed. After surgical exposure of the defect, granulation tissue was removed and implant surface was treated using tetracycline and chlorhexidine. Then, the flaps were sutured. The wound healing was performed in a non-submerged mode. The present finding demonstrates stable results without progression of bone loss. In one subject, deep V shaped bone defect was filled with bone substitute (ICB, CanCellous Bone, Rockey Mountain Tissue Bank, USA), and resorbable membrane (Lyoplant(R), B.Braun Aesculap AG, Germany) was placed over the grafted defect and healing abutment was connected. However, the inflammation was not resolved and more bone loss was found. At one month after regenerative surgery, the implant was removed.]]>
Bone Substitutes ; Chlorhexidine ; Granulation Tissue ; Hygiene ; Inflammation ; Membranes ; Peri-Implantitis ; Tetracycline ; Tissue Banks ; Transplants ; Wound Healing

Authors performed 25 corneal grafts in 24 patients since the inauguration of The Central Eye Bank, attached to the Department of Ophthalmology, St. Mary's Hospital, Catholic Medical College, in April 19, 1967. Method and results of these cases are as follows; METHOD: In technique of surgery, the grafts in most of the cases were 7 mm in diameter(Table 3), in two types of penetrating and lamellar corneal grafts(Table 4). The donor material came from patient age group of 51-60 years old in most and was used within 24 hours after death (Table 5). In most cases we placed 12 interrupted sutures except of two cases for continuous suture by 8-0 virgin silks. Preoperative and postoperative cares were routine with systemic dexamethasone, 7.0mg a day was given routinely on the 5 th postoperative day for 30-50 days because of prevention of graft rejection. RESULTS AND SUMMARY: Table 7 summbrizes the results of our observation. Nineteen of the 25 grafts remained clear. And there was improved vision above 20/200 in ten eyes out of nineteen clear grafts. Table 10 lists the reasons why nine clear grafts did not improve vision. Postoperative complications occurred in fourteen grafts (Table 11). Penetrating corneal grafts for adherent leucoma courneae, staphyloma corneae and corneal scars from alkaline burn were failed to maintaining the clear graft. The donor material, the recipient cornea, graft rejection as a complication and its prevantion were discussed. ACKNOWLEDGEMENTS: We wish to express our sincere gratitude to an those who have guided in carrying out the present investigation. In particular, We are jndebted to Dr. Bon Sool Koo, Former Chief and Professor, Department of Ophthalmology, Catholic Medical College. Dr. Sang Wook Rhee. Chief and Associate Professor, Department of Ophthalmology, Catholic Medical College.
Burns ; Cicatrix ; Cornea ; Corneal Transplantation* ; Dexamethasone ; Eye Banks ; Graft Rejection ; Humans ; Ophthalmology ; Postoperative Complications ; Silk ; Sutures ; Tissue Donors ; Transplants*

We analyzed the result of the tests about HBs Ag, HCv Ag, HIV Ag and VDRL in the blood of the donor and evaluated sex and age distribution, cause of death of the donor, which were obtained from Central Eye Bank at St. Mary's Hospital from January 1, 1993 to December 31, 1994. 1. Hepatitis B surface Ag in the blood was positive in 13 donors(4.80%) and Hepatitis C Ag was in 4 donors(1.48%). 2. VDRL test in the blood was positive in 11 donors(4.06%) and HIV Ag was in 1 donor(0.37%). 3. In sex and age distribution, 128 donors(47.23%) were male and 3 donors(52.77%) were from 71 to 80 years was the major group of donors(67 donors: 24.72%). 4. The most common cause of death was respiratory disease(94 donors: 34.69%) and then tumor(76 donors: 28.04%), circulatory disease(66 donors: 24.35%), metabolic disease (19 donors: 7.01%), infection(9 donors: 3.32%) and trauma(7 donors: 2.58%).
Age Distribution ; Cause of Death ; Eye Banks ; Hepatitis B ; Hepatitis C ; HIV ; Humans ; Male ; Metabolic Diseases ; Tissue Donors*