1.One case of pulsatile tinnitus and literatures review.
Tao WANG ; Jianping LIANG ; Bei LIU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(10):497-500
To investigate the etiology.diagnosis and treatment of pulsatile tinnitus. One case with pulsatile tinnitus in our hospital admitted in May 2012 was reported and the relevant literatures were reviewed. The chief complaint when visited was pulsatile tinnitus. This case was treated by surgery. Pulsatile tinnitus was completely subsided without recurrence. Pulsatile tinnitus is an uncommon otologic symptom, which often presents a diagnostic and treatment dilemma to the otolaryngologist. The majority of patients with pulsatile tinnitus have a treatable cause. Failure to establish correct diagnosis may have disastrous consequences, because a potentially life threatening and underlying disorder may be present.
Adult
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Female
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Humans
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Tinnitus
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diagnosis
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etiology
;
therapy
2.The analysis of masking therapy in the early stage of the patients with noise-induced tinnitus.
Hongsheng CHEN ; Xiaojing LU ; Lingyun MEI ; Xiangning CUI ; Chufeng HE ; Hua ZHANG ; Yong FENG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(1):75-78
OBJECTIVE:
To explore the effect of masking therapy for the early stage of the patients with noise-induced tinnitus,and imply the treatment for patients with noise-induced tinnitus.
METHOD:
Sixty-eight cases with tinnitus were studied. All the patients took the audiological examinations and tinnitus tests firstly, and accepted the masking therapy for 6 months. The therapeutic effiency was evaluated according to tinnitus handicap inventory (THI) and subjective visual-analogue scale (VAS). The minimum masking intensity was also evaluated.
RESULT:
The majority of the patients with noise-induced tinnitus (59 cases, 86. 8%) had tinnitus frequency of 4 kHz,and most of them (44 cases, 64. 7%) had positive residual inhibition tests. Tinnitus completely disappeared in 3 cases after masking therapy, and the efficiency of this treatment is 83. 8%. There was significant difference in the scores of THI and VAS before and after therapy(P<0. 01), and there was also significant difference in the minimum masking intensity (P<0. 01).
CONCLUSION
Masking therapy is the most important treatment for the patients in the early stage of noise-induced tinnitus. The therapeutic effiency is significant and should be promoted.
Humans
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Noise
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adverse effects
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Tinnitus
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etiology
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therapy
3.Scraping needling technique combined with western medication for neurogenic tinnitus of kidney essence deficiency:a randomized controlled trial.
Jiao-Feng CHEN ; Li-Yun CHEN ; Xin ZHENG ; Yu YANG ; Yue-Ting CHEN ; Min-Rui ZHENG
Chinese Acupuncture & Moxibustion 2022;42(9):991-994
OBJECTIVE:
To compare the clinical efficacy of scraping needling technique combined with western medication and simple western medication for neurogenic tinnitus of kidney essence deficiency.
METHODS:
A total of 68 patients with neurogenic tinnitus of kidney essence deficiency were randomly divided into an observation group and a control group, 34 cases in each group. In the control group, oral methylcobalamin tablets were given, 0.5 mg each time, 3 times a day; oral flunarizine hydrochloride capsules were given before bed, 5 mg each time, once a day, 4 weeks in total. On the basis of the treatment as the control group, scraping needling technique was applied at Tinghui (GB 2), Yifeng (TE 17), Yangchi (TE 4) on the affected side and Shenshu (BL 23), Lieque (LU 7), 5 min each acupoint, once a day, 5 times a week for 4 weeks. Before treatment, 2, 4 weeks into treatment and 4 weeks after treatment (follow-up), the tinnitus severity score, tinnitus visual analogue scale (VAS) score and pure tone average (PTA) were observed, and the clinical efficacy was evaluated in the two groups.
RESULTS:
The tinnitus severity scores, VAS scores and PTA of each time point after treatment in the two groups were lower than those before treatment (P<0.05), and those in the observation group were lower than the control group (P<0.05). The total effective rates of each time point after treatment in the observation group were 50.0% (17/34), 79.4% (27/34), 79.4% (27/34), which were higher than 26.5% (9/34), 64.7% (22/34), 61.8% (21/34) in the control group (P<0.05).
CONCLUSION
Scraping needling technique combined with western medication could improve tinnitus severity, tinnitus volume and hearing in patients with neurogenic tinnitus of kidney essence deficiency, and its curative effect is better than simple western medication.
Acupuncture Points
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Acupuncture Therapy
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Humans
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Kidney
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Tinnitus/etiology*
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Treatment Outcome
4.Tinnitus: the mechanism of tinnitus centralization and clinical management.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(4):222-225
Tinnitus is the most common disease in Otology, and extremely difficult for treatment in clinic, abnormal events in the cochlea (the abnormal events can result in abnormal neuronal activity in central auditory pathways that can then be finally perceived as tinnitus). Neuroplasticity events at the auditory cortex (AC) have been reported to include hyperactive of cortical neurons and an increase in neuronal synchronization. Our recent studies showed the changes markedly, in the expression of the excitatory glutamate receptor subtype NR2B in mRNA and protein levels, and also some changes in synaptic ultrastructure of neurons in auditory cortex of tinnitus animal. We propose that the mechanisms of tinnitus centralization may arise from abnormal events in the cochlea, and result in abnormal neuronal activity at multiple levels which promote abnormal propagation of neural activity in the central auditory pathway. The plastic change may be positive and adaptive as with learning or memory, or in the compensation after abnormal events in the cochlea that results in new neuronal networks that restore normal function. Alternatively, the neuroplasticity changes might be maladaptive leading perhaps to an imbalance in excitatory and inhibitory events in the brain. Indeed, tinnitus may be the consequence of such maladaptive neuroplasticity brain alterations (synaptic structure) has even gone a step further and described tinnitus as the perceptual manifestation of plastic brain changes that result in abnormal neuronal activity. The neuroplasticity changes may also make tinnitus persists, eventually leading to the existence of tinnitus cochlear-originated in the central pathway. They may also extend to non-sensory areas of the brain giving rise to the attentional and emotional aspects that often accompany the disorder. New pathophysiological insights maybe prompt the development of management approaches to directly target the neuroplasticity processes correlates of tinnitus.
Auditory Cortex
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Humans
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Neuronal Plasticity
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Tinnitus
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diagnosis
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etiology
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therapy
5.Therapeutic Embolization of the Dural Arteriovenous Malformation Involving the Jugular Bulb.
Jin Young PARK ; Jung Yong AHN ; Byung Hee LEE ; Ryoong HUH ; Hun Kyu CHOI ; Moon Soo SHIN
Journal of Korean Medical Science 2001;16(4):527-531
Pulsatile tinnitus is a rarely occurring symptom of vascular origin. Most frequently, the symptoms are due to an arteriovenous malformation, to a tumor of the jugular glomus or to a local arterial stenosis. A 39-yr-old Korean male suffering from pulsatile tinnitus of the left ear was diagnosed to have dural arteriovenous malformation of the jugular bulb. Magnetic resonance imaging and angiography revealed a high-velocity vascular lesion encroaching the internal jugular vein and sigmoid sinuses. Digital subtraction angiography demonstrated a dural arteriovenous malformation involving the jugular bulb. The arterial supply was from the neuromeningeal branch of the left ascending pharyngeal artery and inferior tympanic artery. Stenosis of the left jugular vein caused retrograde venous drainage through the contralateral transverse sinus. Superselective embolization of these feeding arteries was successfully performed using 25% mixture of N-butylcyanoacrylate and lipiodol. In postembolization period, his complaints of pulsatile tinnitus and buzzing noise behind his left ear disappeared.
Adult
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*Embolization, Therapeutic
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Human
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Intracranial Arteriovenous Malformations/*therapy
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Jugular Veins/*abnormalities
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Male
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Tinnitus/etiology
6.Clinical management strategies of pulsatile tinnitus with transverse sinus stenosis.
Jing XIE ; Yan Jing HAN ; Peng Fei ZHAO ; Na ZENG ; Shu Sheng GONG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2021;56(7):704-712
Objective: To study the clinical diagnosis and treatment strategies for vein-related pulsatile tinnitus patients with transverse sinus stenosis. Methods: The clinical data of patients with vein-related pulsatile tinnitus, from January 2015 to August 2019, were collected,whose digital subtraction angiography showing transverse sinus stenosis. Taking December 2019 as the last follow-up time, we analyzed the clinical characteristics, CT angiography and digital subtraction angiography results, lumbar puncture pressure and cerebrospinal fluid composition, and other auxiliary examination results (pure tone audiometry, fundus examination of papilledema, carotid ultrasonography, bone density screening, endocrinous test), as well as tinnitus handicap inventory, treatment options and follow-up results. Results: 83 patients were enrolled with female of 89.2% (74/83) and male of 10.8%(9/83); 65.1% (54/83) with right tinnitus, 31.3% (26/83) with left tinnitus, and 3.6% (3/83) with bilateral tinnitus; 67.5% (56/83) with right dominant sinus, 19.3% (16/83) with left dominant sinus, 13.3% (11/83) with bilateral equalization; Bilateral and ipsilateral stenosis accounted for 55.4% and 44.6% respectively; BMI was overweight or obese in 41 cases (49.4%, 41/83). Patients with tinnitus handicap inventory level three or above accounted for 79.5% (66/83). Eventually, 33 patients chose conservative observation (39.8%, 33/83), 40 patients (48.2%), 8 patients (9.6%) and 2 patients (2.4%) received sigmoid sinus-related surgery, interventional surgery, or emissary vein occlusion respectively. The mean follow-up time of 74 patients was 26.2 months. The data of 48 surgery patients showed that the pressure differences of venous sinus among the recurrent patients were more obvious; Interventional surgery with simultaneous stenting placement was effective. Tinnitus did not decrease in two patients with emissary vein occlusion. Analysis of 26 patients with lumbar puncture revealed eight cases of normal cranial pressure and 18 cases of high cranial pressure. The sinus pressure difference between the two groups was different (P=0.025), but the difference of age of onset, concomitant symptoms, BMI, proportion of empty sella or papilledema was not statistically significant (P>0.05). Conclusions: The evaluation of patients with vein-related pulsatile tinnitus requires a standardized procedure. Papilledema cannot be used as a sensitive indicator in patients with early intracranial hypertension. Venous sinus pressure difference may be one of the indicators of intracranial hypertension, and the lumbar puncture is the gold standard for the diagnosis. Weight loss can be used as a conservative treatment during the observation period. Significant sinus stenosis is a risk factor for recurrence in patients undergoing sigmoid sinus surgery. Interventional stenting is an effective treatment for tinnitus secondary to transverse sinus stenosis.
Constriction, Pathologic/complications*
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Cranial Sinuses
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Female
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Humans
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Male
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Neoplasm Recurrence, Local
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Stents
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Tinnitus/etiology*
7.Treatment of pulsatile tinnitus associated with multiple factors.
Xiao-Bo MA ; Guo-Peng WANG ; Rong ZENG ; Shu-Sheng GONG
Chinese Medical Journal 2015;128(3):413-414
Adult
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Female
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Humans
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Male
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Middle Aged
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Tinnitus
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etiology
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surgery
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Young Adult
10.Surgical approach for sigmoid sinus diverticulum which caused pulsatile tinnitus.
Zhao-li MENG ; Yu ZHAO ; Yun ZHENG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(6):511-512
Cranial Sinuses
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surgery
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Diverticulum
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complications
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surgery
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Humans
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Male
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Middle Aged
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Tinnitus
;
etiology
;
surgery