OBJECTIVE:To improve the teaching quality of Natural Medicine Foundation and help students better grasp the ba-sic skills of distinguishing common natural medicines. METHODS:Comparison method was used to integrate teaching contents and organize classroom teaching,and the effectiveness of teaching was evaluated. RESULTS:The traditional teaching material system was broke to integrate comparable content together by comparing the common and difference to integrate the content of the compara-bility,comparison of differences in similarities included the comparison of herbal medicinal parts of similar finishing,the compari-son of Chinese medicinal herbs with the same typical characters;comparison of differences in similarities included the comparison of similar overall properties of the herbs,characters of traditional Chinese medicinal materials from different sources,drug name medicine approximation comparison,precious medicinal herbs genuine and counterfeit goods traits. Infiltration comparison method was used in different types of courses and the teaching of different teaching links to guide students to learn to use the comparative thinking to obtain knowledge. CONCLUSIONS:According to the application of comparative method in the teoching of Natural Med-icine Foundation,students have improved the performance and learning ability. It is suggested to apply the comparative method moderately and timely and insist in student-centered,in addition,comparative method shoud be researched and applied with develop-ment view.

Objective To explore the diagnostic significance of the uric acid in preeclampsia.Methods The samples were chosen between January 2008 and August 2015 in our hospital maternity clinic,at 24 to 28 weeks of gestation,singletons,1 357 cases of pregnant women,136 cases for the development of preeclampsia,and 1 221 cases of normal pregnancy.the clinical data of 1 357 cases were retrospectively analyzed.Results (1) The maternal age,birth gestational age,body mass index,systolic blood pressure,diastolic blood pressure,urine protein,cholesterol,creatinine,uric acid,and uric acid increased value of the control group of preeclampsia were significandy higher than the normal group (P ＜ 0.05).The incidence of preeclampsia,cesarean delivery rate,fetal growth restriction,small gestational age,and newborn asphyxia rate of high uric acid hematic disease group were significandy higher than the normal group (P ＜ 0.05).(2) Logistic regression analysis showed that systolic blood pressure,urinary protein and uric acid were the predictors,and uric acid was the best predictor.(3) By using receiver operating characteristic (ROC) curve,the growth of uric acid was 112 μmol/L,and the sensitivity was 85.2％,the specificity was 90.1％.Conclusions Uric acid level can be used as an important indicator to monitor the pathophysiology of preeclampsia,and uric acid value can be accurately predicted.

Objective To compare the status of nurses′cognition on children′s pain between the pediatric intensive care units (PICUs) and common wards .Methods Surveys were completed by the pediatric nurses through the WeChat platform ,3 283 quali‐fied surveys from department of nursing of 11 three level of first‐class hospital in central China ,were sent back and analyzed . Results There was no statistical difference in the age ,marital status ,professional title ,highest academic qualifications ,and the dis‐tribution of professional nursing service life between PICU nurses and common ward nurses(P>0 .05) .Statistical differences were found among the sex ,the positions ,the experiences of nursing and the pediatric nursing (P< 0 .05) .Significant differences were found between the total score of the PNKAS of the PICU nurses and that of common ward nurses(P<0 .05) .Among the four di‐mensionalities ,statistical difference was only found in the item of pharmacological analgesia between PICU nurses and common ward nurses (P<0 .05) .There were no statistical difference on the correct ratio of the top three correct answers and the top three wrong answers between PICU nurses and common ward nurses(P>0 .05) .Conclusion The knowledge of the PICU nurses and common ward nurses were both not optimistic .Specific training should be provided according to the different status of the PICU nurses and common ward nurses ,so that better pain management would be provided to the pediatric children .

Peroxiredoxins(Prxs) are a family of antioxidant protein that have been identified in prokaryotes and eukaryotes. As antioxidants, Prxs protein contains an active site cysteine that is sensitive to oxidation by H 2 O2, eliminate active oxygen that exist in normal tissues and cells, protect cells from oxidative damage induced by reactive oxygen species ( ROS). Prxs protein is a known free radical scavenger, and has been shown to play a role in several diseases. In this review, recent advances on the study of Prxs protein family and tumor related diseases are reviewed, which is expected to provide new ideas for the diagnosis and treatment of the related clinical diseases.

Anniversaries and Special Events ; China ; Humans ; Public Health ; Security Measures ; Sports

Objective To explore the correlation between gratitude and turnover intention of nursing staff.Methods A total of 660 clinical nurses from three general hospitals in Hangzhou city were subject to questionnaire survey for the correlation.Results The multidimensional gratitude totaled 128.33±32.67,at a medium or low level; their turnover intention totaled 14.59 ± 2.26,at a medium level.The multiple factor variance analysis showed statistically significant negative correlations between the three dimensions of gratitude(a sense of rich,simple thanks,and thanks to others)and turnover intention.Conclusion Related departments are recommended to pay close attention to nurses' gratitude and carry out gratitude education,so as to decrease their turnover intention,and keep the career stability of nurses.

ObjectiveTo investigate the feasibility,safety and efficacy of tracheal extubation with directly connected negative pressure suction. Methods86 patients with Ⅰ or Ⅱ degree of ASA,aged 18～65 years old,without history of respiratory disease,difficult airway and ventilation problems were involved in this study.All patients undergoing endotracheal general anesthesia were randomly divided into group A and B with 43 cases in each group.Group A used negative pressure directly connected to external side of the endotracheal tube before extubation.Group B used suction tube putting into the endotracheal tube before extubation.MAP,HR,ECG,SpO2,the condition of cough and expectoration and complicatons after extubation were recorded. ResultsIn group A the MAP,HR slightly increased,SpO2 slightly decreased,ECG showed no significant change,but the differences were not significant.In group B,MAP,HR,SpO2 showed significant difference compared with those before extubation and the corresponding period of group A. ConclusionsThe method that connecting negative pressure suction with endotracheal tube can effectively reduce the cardiovascular response during extubation,It also can avoid hypoxia,reduce the tracheobronchial injury and pulmonary complications.It's a practical good method in tracheal extubation.

OBJECTIVE:To study the general pattern and characteristics of adverse drug reactions (ADR) induced by cimetidine. METHODS: A total of 306 ADR cases induced by cimetidine reported by domestic journals of 1983～2007 were analyzed statistically. RESULTS: The clinical manifestations of ADR induced by cimetidine were complicated and various and characterized by lesions of central nervous system (27.78%), cardiovascular system (21.24%), endocrine disturbance (8.82%) and hematological system (8.82%) etc. CONCLUSION: Great importance should be attached to the ADR induced by cimetidine to guard against the serious ADR such as aplastic anemia, cardiac arrest and allergic shock.

Objective :To Study the Relationship between the Qi Deficiency and Blood Stasis Syndrome and artificial hematogenous metastasis of colon cancer by establishing a compound model of Qi Deficiency and Blood Stasis Syndrome and artificial hematogenous metastasis of colon cancer. Methods:Thirty six eight-weeks old female Balb/c rats were divided into six groups randomly:control group ,stasis group,tumor groupA、B ,stasis and tumor groupA、B. We observed the survival time of tumor groupB and stasis and tumor groupB. At the 28th day,after killing the mice of the other groups,we detected the whole blood viscosity and the amounts of metastasis tubercle on lung. Results:The weight of the stasis group increase more slowly than control group(P

Objective To establish a method for the determination of methyl tertiary butyl ether (MTBE) in the cerebrospinal fluid of rats by gas chromatography and to know whether MTBE can penetrate the blood brain barrier. Methods 9 male SD rats were randomly divided into 3 groups and then exposed to MTBE by gavage at a dose of 1000 mg/kg?bw and by inhalation at a dose of 8 ml/L for 30 days. The cerebrospinal fluid was collected at 6 h, 12 h and 24 h respectively at the end of treatment and the MTBE in rats cerebrospinal fluid was determined by gas chromatography. Results MTBE was detected in the cerebrospinal fluid of rats after subchronic exposure of MTBE through gavage and inhalation. Conclusion MTBE is able to penetrate the blood brain barrier and reach the brain.