1.Synthetic application of health belief model and theory of reasoned action/planned behavior in studies related to health behaviors
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(3):284-288
Objective Health belief model and theory of reasoned action or theory of planned behavior have been used widely in studies of health behavior and combined to use in many studies to explain and predict definite health behaviors.A systematic review was conducted to analyze how two theories combined in the studies related to health behaviors,to explore general factors influencing different health behaviors,and so that to provide evidence for future health promotion and health education strategies.Methods Nine databases were searched using predetermined search strategies and 322 indexes were identified.Key information of included studies was extracted and the quality of each one was assessed according to Strobe Checklist and Cochrane Handbook for Systematic Reviews of Interventions.Results 40 papers including 37 studies were finally included in this review.6 studies were of high quality,while others were of medium quality.Most studies were cross-sectional survey.Two theories were usually as the framework basis and used to develop research instruments in the included studies.Some researchers used behavioral intention as an outcome variable instead of actual behavior.Subjective norms,perceived susceptibility,and perceived behavior control were the most influencing factors for behavioral intention;perceived barriers,behavioral intention,and perceived behavior control were the most influencing factors for behavior.Conclusions There are some limitations need to avoid in the future studies synthetically using HBM and TRA/TPB.Improving individuals' perceived susceptibility and subjective norms by extending the target population can serve as the common intervention to change health behaviors;further studies should identify individuals' perceived barriers and control beliefs of specific behaviors,and make responding interventions.
2.Effect of Psychological Consultation on post Stroke Depression
Fei GAO ; Jing ZHU ; Jing-ting PENG
Chinese Journal of Rehabilitation Theory and Practice 2012;18(12):1141-1143
Objective To explore the effect of early screening and psychotherapy on post stroke depression. Methods 80 patients with stroke at first onset were assessed with Hamilton Rating Scale for Depression (HAMD-17). Patients with depression were divided into control group (n=21) and intervention group (n=21). Both groups received rehabilitation therapy and the intervention group received psychotherapy in addition. They were assessed with HAMD again 2 months after treatment. All of them were evaluated with modified Barthel index (MBI). Results 52.5% patients had post stroke depression. The score of HAMD-17 was lower in the intervention group than in the control group (P<0.01). There was no significant difference in MBI between 2 groups after treatment (P>0.05). Conclusion Early screening and psychotherapy can facilitate the recovery of patients with depression after stroke.
3.Application of posterior scleral reinforcement in high myopic maculopathy
jing-rong, SHI ; Ying, FAN ; Ting-Ting, ZHAO
International Eye Science 2015;(7):1187-1189
The rate of blinding caused by high myopic maculopathy is high, vitrectomy is the most common treatment. However, the effectiveness of vitrectomy for high myopic patients who have serious posterior scleral staphyloma is not ideal. Recent years, posterior scleral reinforcement is used as a supplementary method with vitrectomy in clinical, treating for high myopic maculopathy. lt achieves a positive curative effect especially in macular foveoschisis and macular hole cases. ln this article, we introduced a review of history, current situation, material and surgery operand of scleral reinforcement. lt also makes a further discussion of its prospects used in retina surgery.
4.Role of Cripto-1 protein in development and target therapy of breast cancer.
Ting LEI ; Xiao-jing GUO ; Li FU
Chinese Journal of Pathology 2010;39(1):66-68
Animals
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Antibodies, Monoclonal
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metabolism
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therapeutic use
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Biomarkers, Tumor
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metabolism
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Breast Neoplasms
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metabolism
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pathology
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therapy
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Drug Delivery Systems
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Epidermal Growth Factor
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immunology
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metabolism
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physiology
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Epithelial-Mesenchymal Transition
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GPI-Linked Proteins
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Humans
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Immunotherapy
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methods
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Intercellular Signaling Peptides and Proteins
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Membrane Glycoproteins
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immunology
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metabolism
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physiology
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Neoplasm Invasiveness
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Neoplasm Metastasis
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Neoplasm Proteins
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immunology
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metabolism
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physiology
5.Effect of psychological counseling skills on nurse-patient communication
Jing CHEN ; Derong LONG ; Ting ZHANG
Modern Clinical Nursing 2016;15(12):29-32
Objective To explore the effect of psychological counseling skills on medical treatment and satisfaction degree of patients in hospital.Methods Toally 60 discharged patients during December 2015 were assigned as the control group and another discharged one during January 2016 as the intervention group.Training on psychological counseling skills was done for the nurses by the psychological counselor in the intervention group while the control group was not.The two groups were compared on the basis of investigation with the patient's consultation experience scale as well as the medical satisfaction questionnaire.Result The satisfaction levels of consultation experience and medical consultation satisfaction in the intervention group were both higher than those of the control group (all P<0.01).Conclusion Psychological counseling skills used in the nurse patient communication can enhance the patient's medical experience and their satisfaction with medical treatment.
6.The study of relationship between the levels of plasma VEGF,PAI-1 and the severity of the diabetic retinopathy
Chinese Journal of Practical Internal Medicine 2000;0(12):-
Objective To observe the relationship between the levels of plasma VEGF,PAI-1 and the severity of the diabetic retinopathy in type 2 diabetic patients.Methods ELISA method was used to measure the levels of VEGF and PAI-1.Results The level of VEGF was increased in all diabetic patients compared with the normal control group[(17.86?12.25)ng/L],and that of the patients with BDR[(93.41?54.69)ng/L]was higher than that of the patients with NDR[(52.17?21.81)ng/L]and PDR[(61.24?37.55)ng/L].The level of PAI-1 was also increased in all diabetic patients.The increase tendency was more obvious in patients with BDR[(58.29?20.53)?g/L]and PDR[(66.84?23.81)?g/L].Conclusion The damage of the vascular endothelial cell and the impaired fibrinolysis state exist in diabetic retinopathy.So it is very important to measure the levels of VEGF and PAI-1 for the early diagnosis and intervention treatment of diabetic retinopathy.
7.Study on cytomegalovirus gene mutations conferring resistance to ganciclovir in heart and lung transplant patients
Lin ZHOU ; Jing QIAN ; Ting CAI
Chinese Journal of Infectious Diseases 1999;0(01):-
Objective To establish a rapid and convenient assay to screen for emerging ganciclovir(GCV) resistant mutations in the UL97 gene of human cytomegalovirus (HCMV) from transplant recipients. Methods Thirteen spefcific oligonucleotide probes were designed according to the target sequence encoding HCMV-UL97 gene. A nested polymerase chain reaction (PCR) amplifying UL97 gene was employed. Line probes assay (LiPA) was configured to detect relevant non-synonymous mutations at codon 460,520,594,595,603, and 607. In parallel, nested-PCR amplicons were subsequently sequenced directly. Results Four of 16 heart and lung transplant recipients had been infected with HCMV resistant strains during GCV therapy. The mutant codons of UL97 gene were at codon 520、595 and 603. All amplicons detected by LiPA were fully concordant with the nucleotide sequenced.Conclusions Long-term prophylaxis and treatment with GCV in heart and lung transplant recipients may develop HCMV resistant strains. HCMV-LiPA proves to be an alternative method for the resistance genotype analysis of HCMV.
8.Clinical efficacy observation on therapy ovulation failure infertility caursed by PCOS with reinforcing kidney, activating blood circulation and ovarian stimulation compound recipe.
Xuan-Ting JIN ; Kun MA ; Jing SHAN
China Journal of Chinese Materia Medica 2014;39(1):140-143
To investigate the clinical effect of tonifying the kidney and promoting blood circulation to promote oocyte decoction in the treatment of anovulatory infertility caused by polycystic ovary syndrome. Sixty cases were selected from the out-patient department of Xiyuan hospital of China academy of Chinese medical sciences and the Chinese academy of traditional Chinese medicine, Chinese medicine out-patient department. Sixty patients with PCOS patients were randomly divided into the treatment group and the control group, with 30 cases and 30 cases respectively. The treatment group was given decoction of the reinforcing kidney, activating blood circulation and ovarian stimulation compound recipe. The control group was treated with clomiphene. Through the treatment of 1-2 courses, in the treatment group the pregnancy rate was 56.67%, the ovulation rate 61%; in control group of clomiphene citrate ovulation ratepregnancy rate was 30% , 72.84% of ovulation rate. The difference was significant between two groups (P < 0.05), the pregnancy rate in the treatment group was higher than the control group. The treatment group has regulatory effect on FSH, LH and their ratio, and increase E2 level, decrease T, PRL, INS and other hormone levels, contributing to the mature development of the follicles and endometrium growth, increase the ovulation rate and pregnancy rate. The control group on FSH, E2 increased, LH, T, PRL and INS showed no obvious effect.
Adult
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Drugs, Chinese Herbal
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pharmacology
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Female
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Fertility Agents, Female
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pharmacology
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Humans
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Infertility, Female
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drug therapy
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etiology
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Kidney
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drug effects
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Ovulation
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drug effects
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Ovulation Induction
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Polycystic Ovary Syndrome
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complications
9.Clinical analysis of the surgical diagnosis and treatment of 60 patients with traumatic liver rupture
Jing GAO ; Yunbin DENG ; Ting WANG
Chinese Journal of Primary Medicine and Pharmacy 2012;19(21):3238-3239
Objective To explore clinical diagnosis and surgical treatment for the traumatic liver rupture.Methods The clinical data of 60 cases with traumatic liver rupture were retrospectively cralyzed to explore the diagnosis and surgical treatment.Results 45 injury patients were diagmosed by,patient history,signs and imaging studies.15 cases of blunt injury,five cases diagnosed by above methods,10 cases of diagnostic peritoneal puncture are positive diagnosis.28 cases received the left hepatic lobe partial resection,20 cases right lobe partial resection,12 cases had the left hepatic lobe and right lobe partial nephrectomy.Among 60 patients,5 cases(8.33%) were dead and the other 55 patients,8 cases occured postoperative complications,were discharged after symptomatic treatment,the average length of stay was (15.6 ± 3.5) days.Conclusion Traumatic liver rupture is a critical illness,rapid and correct diagnosis before surgery,and choose the correct surgical approach,focusing on merger deal with injuries to postoperative complications,and improve the treatment success rate.
10.Bioequivalence of Pidotimod Granules and Pidotimod Syrup in Healthy Volunteers
Wei LIU ; Jing CHEN ; Ting XIONG
China Pharmacy 2005;0(20):-
OBJECTIVE:To evaluate the bioequivalence of the domestic pidotimod granules with the imported pidotimod syrup as control.METHODS:20 healthy male volunteers were treated with a single dose(800 mg)of pidotimod granules(test formulation)or pidotimod syrup(reference formulation)by a randomized crossover design,with plasma concentrations of pidotimod determined by HPLC and pharmacokinetic parameters of pidotimod computed,and the bioequivalence between two formulations was evaluated using DAS2.0 program.RESULTS:The pharmacokinetic parameters of the reference formation vs.the test formulation of pidotimod were expressed as follows:t1/2(2.70?0.80)h vs.(2.62?0.84)h;Cmax(4.04?0.59)?g?mL-1 vs.(3.87 ?0.66)?g?mL-1;tmax(2.28?0.44)h vs.(2.13 ?0.43)h;AUC0~14(22.11?4.20)mg?h?L-1 vs.(23.00?4.25)mg?h?L-1;AUC0~∞(22.85?4.42)mg?h?L-1 vs.(23.83?4.52)mg?h?L-1.The relative bioequivalence of the test formulation as against the control was(106.08?22.05)%.CONCLUSION:The pidotimod granules and pidotimod syrup are bioequivalent.