OBJECTIVETo observe the effect of Qingre Yangyin Recipe (QRYYR) on sex hormones and insulin resistance (IR) in polycystic ovary syndrome (PCOS) patients.

METHODSTotally 90 PCOS patients were randomly assigned to the Chinese herbs group,the Western medicine group, the combined group, 30 in each group. Patients in the Chinese herbs group took QRYYR, one dose per day in two portions, once in the morning and once in the evening. Patients in the Western medicine group took Metformin 500 mg, twice per day for 3 consecutive months. Patients in the combined group took QRYYR and Metformin (the same as the former said two groups) in the 1st month, and took QRYYR for the following two months. Fasting blood glucose (FPG) and postprandial 2 h blood glucose (2 h GLU) were determined using hexokinase method before and after treatment. Fasting insulin (FINS), postprandial 2 h insulin (2 h INS), luteinizing hormone (LH), follicle stimulating hormone (FSH), estradiol (E2), progesterone (P), prolactin (PRL), and testosterone (T) were detected using chemiluminescent method. Leptin and adiponectin (APN) were determined using ELISA. Homeostasis model assessment of insulin resistance (HOMA-IR) was calculated. Body weight and height were measured once before treatment and once after treatment to calculate body mass index (BMI). The total two-phase basal body temperature (BBT) actually obtained within 3 months was statistically collected to calculate the two-phase BBT rate. Scores for Chinese medical syndromes were compared between the two groups before and after treatment.

RESULTSCompared with before treatment in the same group, BMI, FINS, 2 h INS, HOMA-IR, leptin, LH, PRL, T, and scores for Chinese medical syndromes obviously decreased, and APN levels increased (P < 0.05). FPG and 2 h FPG obviously decreased in the Western medicine group and the combined group (P < 0.05). E2 levels obviously decreased in the combined group with statistical difference (P < 0.05). Compared with the Chinese herbs group, the difference of BMI between pre-treatment and post-treatment was more in the combined group (P < 0.05). The difference of FPG,2 h GLU, 2 h INS, HOMA-IR, and APN between pre-treatment and post-treatment was more in the Chinese herbs group and the combined group (P < 0.05). Compared with the Western medicine group, the difference of PRL, T, and scores for Chinese medical syndromes was more in the Western medicine group and the combined group (P < 0.05); the difference of E2 and LH was even more in the combined group (P < 0.05). Compared with the combined group, the biphasic rate was obviously lowered in the Western medicine group (P < 0.05).

CONCLUSIONSQRYYR could improve IR but with weaker power to that of Metformin. It also could decrease serum levels of LH, T, PRL, and scores for Chinese medical syndromes, with superior effect to that of Metformin. The effect in the combined group was better.

Adiponectin ; Blood Glucose ; Body Mass Index ; Drugs, Chinese Herbal ; pharmacology ; therapeutic use ; Estradiol ; Female ; Follicle Stimulating Hormone ; Gonadal Steroid Hormones ; Humans ; Insulin ; Insulin Resistance ; Leptin ; Luteinizing Hormone ; Metformin ; Polycystic Ovary Syndrome ; drug therapy ; metabolism ; Progesterone ; Prolactin ; Testosterone

Objective To describe the status of resilience and self-care behaviors in chronic heart failure patients and to explore the relationship between resilience and self-care behaviors. Methods It was a cross-sectional survey. The Connor-Davidson Resilience Scale, the self-care behaviors with heart failure questionnaire and the demographic scale were delivered to 150 chronic heart failure patients in Shanghai Changhai Hospital. Results The score of self-care behaviors was (2.63 ± 2.01) points for chronic heart failure patients. The resilience score was (57.56 ± 8.51) points. The resilience was significantly related to the self-care behaviors(r=0.427, P<0.01), and which explained 32.4%of the total variation. Conclusions The chronic heart failure patients have poor self-care behaviors and resilience. More attention should be paid and more action be taken to improve the resilience, then improve the self-care behaviors of patients.

Pneumonia is the primary cause of death in children under five-years old.About 2 million children younger than 5 years die of pneumonia each year worldwide,accounting for 19％ of the total number of deaths.According to the survey in 2008,7％ to 13％ of the children with pneumonia were severe pneumonia.Currently,the early diagnosis and treatment of severe pneumonia is often difficult.In order to improve the early diagnosis an prognosis cognition level of severe pneumonia,here is to make a review on the recent literatures on the biomarkers like brain natriuretic peptide,D-Dimer,C-reactive protein,lactate,zinc,procalcitoin,prealbumin,platelet count,endothelin-1 and high mobility group box 1 in children with severe pneumonia.

Objective]To investigate the effect of improving the treatment of hyperlipidemia simvastatin treatment. [Methods] From October 2012 to February 2014 in our hospital 80 cases of patients with hyperlipidemia were randomly divided into four groups, each of 20 cases, namely group A (simvastatin), group B(Xinmaitong capsule and simvastatin), group C(acupuncture and simvastatin group) and group D(acupuncture, Xinmaitong capsule and simvastatin group), for 1 consecutive month of treatment, patients were observed before and after total cholesterol, triglycerides esters, LDL and HDL changes. [Results] Group A was 70%;the effective rate was 85% in group B; group C, the effective rate was 80%; D group was 95%, the difference was statistically significant(P<0.05), and the combined group of high-density lipoprotein increased significantly. [Conclusion] Combination therapy medicine was more efficient than single, the enhanced effect of high-density lipoprotein was obvious, what ’s more,the effect of acupuncture, Xinmaitong capsule and simvastatin group was better than others.

OBJECTIVE:To establish quality criteria for Bushenqiangshen capsule. METHODS:TLC was employed to identify Herba Epimedii and Fructus Ligustri Lucidi. HPLC was applied for the determination of content of Icariin. The chromatographic separation was performed on octadecylsilane chemically bonded silica packed column (250mm?4.6mm,5?m). The mobile phase was composed of acetonitrile and methyl alcohol (30∶70) at a flow rate of 1.0mL?min-1. The detection wavelength was 270nm and the column temperature was 30℃. RESULTS:Herba Epimedii and Fructus Ligustri Lucidi were well-separated and clear spots were noted in their TLC. The linear range of icariin was 0.266 4～0.932 4?g (r=0.999 9,n=6), and the average recoveries was 99.77%(RSD=1.89%). CONCLUSION:The established criteria can be used for the quality control of Bushenqiangshen capsules.

OBJECTIVE:To improve the teaching quality of Natural Medicine Foundation and help students better grasp the ba-sic skills of distinguishing common natural medicines. METHODS:Comparison method was used to integrate teaching contents and organize classroom teaching,and the effectiveness of teaching was evaluated. RESULTS:The traditional teaching material system was broke to integrate comparable content together by comparing the common and difference to integrate the content of the compara-bility,comparison of differences in similarities included the comparison of herbal medicinal parts of similar finishing,the compari-son of Chinese medicinal herbs with the same typical characters;comparison of differences in similarities included the comparison of similar overall properties of the herbs,characters of traditional Chinese medicinal materials from different sources,drug name medicine approximation comparison,precious medicinal herbs genuine and counterfeit goods traits. Infiltration comparison method was used in different types of courses and the teaching of different teaching links to guide students to learn to use the comparative thinking to obtain knowledge. CONCLUSIONS:According to the application of comparative method in the teoching of Natural Med-icine Foundation,students have improved the performance and learning ability. It is suggested to apply the comparative method moderately and timely and insist in student-centered,in addition,comparative method shoud be researched and applied with develop-ment view.

This paper probes into problems about the change of hospital economic interest and moral relation etc. brought by trying out medical insurance system in Zhengjiang, Jiujiang City. Also in points out that economic states have influence on ethical concept. Ethical concepts have a role on economic behaviour, which are two sides of cause and effect chain. For these reasons, medical insurance system is mutual movement results of economic & ethical factors, It can coordinate the relationships between hospital economic interest and morality embody medical service fairness and economic moral principles.

Acute Disease ; Adult ; Female ; Humans ; Male ; Organometallic Compounds ; poisoning ; Poisoning ; therapy

Adult ; Burns, Inhalation ; diagnostic imaging ; Female ; Humans ; Male ; Middle Aged ; Radiographic Image Enhancement ; methods ; Radiography, Thoracic ; methods

Congenital Abnormalities ; etiology ; Deficiency Diseases ; complications ; Female ; Humans ; Maternal Nutritional Physiological Phenomena ; Pregnancy