The distributioa of Se in Hb and the effects of Se intake and its chemical forms oil the distribution were studied. The results showed that Se in human Hb was all located in globin and divided equally in a and ? chains. However, a part of Se could fall from Hb during the process of isolation when more Se as SeMet was taken and "excess" Se appeared in Hb. It was implicated that there were at least two kinds of linkage between Se and Hb --tight and loose.Regarding the components of amino acid in ? and ? chains, we assumed that a tight linkage between Se and Hb was in the form of SeMet, which was incorporated into Hb by dietary Se during the synthesis of Hb; the loose linkage was formed by a part of "excess" Se and CyS, especially No.93 CyS in ? chain, being unstable sclcnotrisulf ide or selenopersulfide, which broke easily by reduction during isolation. They might be utilized first by human body when Se was required.

Objective To investigate the effects of oxiracetam combined with rosuvastatin on levels of serum hs-CRP,IL-1 β and IL-6 in patients with cerebral infarction.Methods A total of 100 patients with cerebral infarction were selected and randomly divided into observation group and control group.The control group was given conventional cerebral infarction treatment,and the observation group was given oxiracetam combined with rosuvastatin.The clinical efficacy and levels of hsCRP,IL-1β and IL-6 before and 14 days after treatment were compared.Results After treatment,the total effective rate of the observation group was significantly higher than the control group (P ＜0.05).After treatment,the levels of hs-CRP,IL-1β,IL-6 improved significantly in both groups (P ＜ 0.05),and which in the observation group was significantly better than control group (P ＜0.05).Conclusion Oxiracetam combined with rosuvastatin is effective in treatment of patients with cerebral infarction,and it can significantly improve the levels of hs-CRP,IL-1 β and IL-6.

Objective To investigate the effects of oxiracetam combined with rosuvastatin on levels of serum hs-CRP,IL-1 β and IL-6 in patients with cerebral infarction.Methods A total of 100 patients with cerebral infarction were selected and randomly divided into observation group and control group.The control group was given conventional cerebral infarction treatment,and the observation group was given oxiracetam combined with rosuvastatin.The clinical efficacy and levels of hsCRP,IL-1β and IL-6 before and 14 days after treatment were compared.Results After treatment,the total effective rate of the observation group was significantly higher than the control group (P ＜0.05).After treatment,the levels of hs-CRP,IL-1β,IL-6 improved significantly in both groups (P ＜ 0.05),and which in the observation group was significantly better than control group (P ＜0.05).Conclusion Oxiracetam combined with rosuvastatin is effective in treatment of patients with cerebral infarction,and it can significantly improve the levels of hs-CRP,IL-1 β and IL-6.