1.Features of arterial blood gas in the exacerbation of the chronic obstructive pulmonary disease
Journal of Practical Medicine 1999;366(6):46-48
A measurement of arterial blood gas in the exacerbation of 54 patients with the chronic obstructive pulmonary disease shown that the arterial PaO2 was reduced in 20 patients (37%) and arterial PaCO2 was increased in 30 patients (55.6%). Among patients with the reduction of arterial PaO2¬, 14 patients experienced the respiratory failure, mainly type II respiratory failure. During the exacerbation of the disease, the arterial PaO2 reduction can occur in all 3 stages of the COPD.
Pulmonary Disease, Chronic Obstructive
;
diagnosis
2.Studying on characters of pulmonary ventilation in 90 patients with exacerbations of COPD
Journal of Practical Medicine 1998;354(9):37-39
Between April 1994 and May 1998, 90 patients with exacerbations of COPD were recruited in this study. Pulmonary ventilation was measured and evaluated using ATS criteria. The results showed that most of participants had combined ventilatory dysfunction (93.3%) and stage 1 or 2 of COPD (87.7%). 53.3% of patients were in stage 3 of COPD. There was not any relationship between FEV1 and chronic productive cough (r = -0.04). The instantaneous flow rates at different percentages of the FVC (MEF75%, MEF50%, MEF25%), PEF and PEF25-75% all decreased more than FEV1. There was not relationship between FEV1 and PEF, PEF25-75%, MEF75%, MEF50%, MEF25%. PEF was unreplaceable for FEV1 in diagnosis and monitoring COPD. After treatment, all these measurements increased partially (less than 15%).
Pulmonary Disease, Chronic Obstructive
;
pulmonary ventilation
3.Assessing the emergency situation for peripheral vascular wounds/trauma in Viet Duc Hospital from 2004 to 2006
Uoc Huu Nguyen ; Nghia Dinh Che ; Hung Duc Duong ; Hung Quoc Doan ; Huu Cong Nguyen ; Lu Huu Pham ; Tien Anh Do ; Thanh Ngoc Le
Journal of Surgery 2007;4(57):12-19
Background: peripheral vascular wounds/trauma is a severe type of surgical emergency, the increasing rate due to the rapid increase of traffic, labor and living accidents. Subjectives and Method: retrospective study, all patients with peripheral vascular wounds/traumas (alone or combination in multiple trauma) were emergency operated at Viet Duc Hospital from January 2004 to June 2006. Results: A total of 310 patients with peripheral vascular injuries in the study, of which accounted for 62.3% of injury, trauma group accounted for 37.7%. The mean age of 30. In first aid, pressed tape accounted for high rate (71.5%). Rate of popliteal vascular trauma due to fractures around the knee accounted for 65.5%, the rate of brachial vascular trauma with fractures around the elbow was 50%. Rate of late diagnosis of arterial trauma was 14.6%, higher than the arterial wounds (2.6%). The rate of ultrasound for forelimbs - where vessels were many wounds, was lower than that for hindlimbs - where vessels were many traumas (44% vs 67.9%). For vascular wounds, more directly vascular connection and more intervention on veins, whereas, for arterial trauma, more vascular graft. Rate of complications was low (7.4%), with no deaths. Conclusions: Overall, the results of emergency surgery for peripheral vascular wounds/trauma were well. No cases was death from vascular lesions, rate of complications was low.
Blood Vessels/ injuries
;
Emergencies
;
4.BONEcheck: A digital tool for personalized bone health assessment
Dinh Tan NGUYEN ; Thao P. HO-LE ; Liem PHAM ; Vinh P. HO-VAN ; Tien Dat HOANG ; Thach S. TRAN ; Steve FROST ; Tuan V. NGUYEN
Osteoporosis and Sarcopenia 2023;9(3):79-87
Objectives:
Osteoporotic fracture is a significant public health burden associated with increased mortality risk and substantial healthcare costs. Accurate and early identification of high-risk individuals and mitigation of their risks is a core part of the treatment and prevention of fractures. Here we introduce a digital tool called 'BONEcheck' for personalized assessment of bone health.
Methods:
The development of BONEcheck primarily utilized data from the prospective population-based Dubbo Osteoporosis Epidemiology Study and the Danish Nationwide Registry. BONEcheck has 3 modules: input data, risk estimates, and risk context. Input variables include age, gender, prior fracture, fall incidence, bone mineral density (BMD), comorbidities, and genetic variants associated with BMD.
Results:
Based on the input variables, BONEcheck estimates the probability of any fragility fracture and hip fracture within 5 years, subsequent fracture risk, skeletal age, and time to reach osteoporosis. The probability of fracture is shown in both numeric and human icon array formats. The risk is also contextualized within the framework of treatment and management options on Australian guidelines, with consideration given to the potential fracture risk reduction and survival benefits. Skeletal age was estimated as the sum of chronological age and years of life lost due to a fracture or exposure to risk factors that elevate mortality risk.
Conclusions
BONEcheck is an innovative tool that empowers doctors and patients to engage in wellinformed discussions and make decisions based on the patient's risk profile. Public access to BONEcheck is available via https://bonecheck.org and in Apple Store (iOS) and Google Play (Android).
5.Study on the effective control of postpreal blood glucose of resistant starch cakes in patients with type 2 diabetes
Huu Dung TRAN ; Quang Hung LE ; Bao Dung VO ; Hoang Vu NGUYEN ; Thanh Bao Yen LUONG ; That Hy TON ; Phuoc Hieu DOAN ; Thi Bich Hien PHAM ; Huu Tien NGUYEN ; Hai Thuy NGUYEN
Hue Journal of Medicine and Pharmacy 2023;13(7):52-58
Background: This study was conducted on 93 volunteers with type 2 diabetes to investigate the ability of acetylated wheat starch cake containing 32.1% resistant starch to control postprandial blood glucose levels. Material and methods: The study was designed using a crossover, double-blind trial method. During each testing day, after a minimum of 12 hours of overnight fasting, each participant consumed two identical cakes containing either 80 g of acetylated wheat starch or 80 g natural wheat starch with 330ml of water within 15 minutes. Blood glucose levels were measured at baseline, 60 mins (G1), and 120 mins (G2) after ingestion. The predictive value of factors that contribute to the ability of resistant starch to control postprandial blood glucose was determined by the area under the receiver operating characteristic (ROC) curve based on the combined effect of the cake weight-to-BMI ratio (g/m²BMI) and HbA1c. Results: 60 mins and 120 mins postprandial capillary glucose levels after consuming acetylated wheat starch cake (10.4 ± 1.2 và 9.2 ± 1.2 mmol/L, respectively) were significantly lower compared with natural wheat starch cake (13.3 ± 1.8 và 11.2 ± 1.8 mmol/L, respectively) (p < 0.05). For good control of postprandial blood glucose levels, a maximum of 80 g of acetylated wheat starch can be used per serving for patients with type 2 diabetes with HbA1c ≤ 7.25 without blood glucose-lowering medication is required. Conclusion: acetylated wheat starch has better ontroled of postprandial blood glucose compared with natural wheat starch in patients with type 2 diabetes. This is very suitable in the processing of diets including resistant starch for patients with type 2 diabetes for the purpose of both supporting treatment and improving quality of life.
6.Ischemic Colitis Presented as Pseudomembranous Colitis: An Untypical Case from Vietnam
Tien Manh HUYNH ; Quang Dinh LE ; Khanh Lan NGUYEN BUI ; Minh Quang HUYNH BUI ; Cong Minh HONG VO ; Duc Trong QUACH
The Korean Journal of Gastroenterology 2022;80(2):93-98
Ischemic colitis (IC) is an underreported chronic disease characterized by the hypoperfusion of the bowel mucosa. The diagnosis and treatment may be challenging because its clinical course resembles other colitis or even colorectal malignancies. This paper reports an untypical case to underline the diversity of IC manifestation. A 68-year-old man with several comorbidities was admitted because of abdominal pain with a 6-month duration and a mass in the left lower quadrant. Colonoscopy revealed erosive pseudomembranous colitis narrowed colon segments with ulcerated mucosa mimicking colorectal cancer and inflammatory bowel disease. The stool cultures and Clostridium difficile toxin tests were negative. After the failure of conservative therapy, the Hartmann procedure with temporary ileostomy was performed uneventfully. The histological results of the surgical specimens revealed IC with focal pseudomembranous areas.