1.Recent neuroanatomical studies on the neurovascular bundle of the prostate and cavernosal nerves: clinical reflections on radical prostatectomy.
Selcuk YUCEL ; Tibet ERDOGRU ; Mehmet BAYKARA
Asian Journal of Andrology 2005;7(4):339-349
The neurovascular bundle of the prostate and cavernosal nerves have been used to describe the same structure ever since the publication of the first studies on the neuroanatomy of the lower urogenital tract of men, studies that were prompted by postoperative complications arising from radical prostatectomy. In urological surgery every effort is made to preserve or restore the neurovascular bundle of the prostate to avoid erectile dysfunction (ED). However, the postoperative potency rates are yet to be satisfactory despite all advancements in radical prostatectomy technique. As the technology associated with urological surgery develops and topographical studies on neuroanatomy are cultivated, new observations seriously challenge the classical teachings on the topography of the neurovascular bundle of the prostate and the cavernosal nerves. The present review revisits the classical and most recent data on the topographical anatomy of the neurovascular bundle of the prostate and cavernosal nerves and their implications on radical prostatectomy techniques.
Erectile Dysfunction
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prevention & control
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Humans
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Hypogastric Plexus
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anatomy & histology
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Male
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Postoperative Complications
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prevention & control
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Prostate
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innervation
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surgery
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Prostatectomy
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methods
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Prostatic Neoplasms
;
surgery
2.Intratunical bupivacaine and methylprednisolone instillation for scrotal pain after testicular sperm retrieval procedures.
Gul K TALU ; Tibet ERDOGRU ; Tansel KAPLANCAN ; Mustafa BAHCECI
Asian Journal of Andrology 2003;5(1):65-67
AIMTo investigate the effect of intratunical instillation of bupivacaine and methylprednisolone for scrotal pain, swelling and peritesticular fibrosis due to testicular sperm retrieval procedures.
METHODSA total of 65 patients were randomly divided into two groups. In the instillation group (GI), 34 patients were administered 2.5 mL of 0.5 % bupivacaine combined with 10 mg/ml methylprednisolone before closure of the tunica vaginalis. In the control group (GC), 31 patients only received analgesics postoperatively by intramuscular route. The pain (by visual analogue scale, VAS) and duration of pain-free period after surgery between the two groups were evaluated at 2 and 4 h and at days 2 and 7 postoperatively.
RESULTSThe mean pain scores were significantly lower in the GI than in the GC group at 2 and 4 h after surgery (P<0.05 and P<0.01, respectively). The mean duration of pain free interval after the procedure was 47.8 +/-16.9 (12-72) h in GI, which was significantly longer than that in GC [(9.9 +/-3.6; 4-20) h]. Besides, in the GI, 29 % of patients were completely free from pain and 67 % had no scrotal swelling, but in the GC, all the patients required additional NSAID injection due to pain and only 3 % had no scrotal swelling.
CONCLUSIONThis study confirms that direct intratunical instillation of bupivacaine and methylprednisolone around the testis reduces the postoperative pain, scrotal swelling and peritesticular fibrosis.
Adult ; Anesthetics, Local ; administration & dosage ; Anti-Inflammatory Agents ; administration & dosage ; Bupivacaine ; administration & dosage ; Humans ; Male ; Methylprednisolone ; administration & dosage ; Oligospermia ; surgery ; Pain, Postoperative ; drug therapy ; Scrotum ; Spermatozoa ; cytology ; Treatment Outcome
3.Evaluation of penile hemodynamic status and adjustment of treatment alternatives in Peyronie's disease.
Tibet ERDOGRU ; Murat SAVAS ; Namik YILMAZ ; Mustafa Faruk USTA ; Turker KOKSAL ; Mutlu ATES ; Mehmet BAYKARA
Asian Journal of Andrology 2002;4(3):187-190
AIMErectile dysfunction may be observed in up to 80% of patients with Peyronie's disease. An objective evaluation of the erectile function is attempted to work out in patients with Peyronie's disease.
METHODSPenile deformity, sexual function and penile vascular status were analyzed in 123 patients with Peyronie's disease, who had not received any pertinent treatment.
RESULTSPenile deformity, palpable plaque and pain on erection were seen in 112 (91%), 97 (78.8%) and 27 (21.9%) of the 123 patients, respectively. Of the 76 patients evaluated by color Doppler ultrasounography, veno-occlusive dysfunction as the vascular component for erectile dysfunction was found in 17 (22.3%), arterial insufficiency in 10 (13.1%) and a mixed picture in 23 (30.2%).
CONCLUSIONThe documentation of penile erectile function and the determination of the vascular status using color Doppler ultrasonography can guide the appropriate therapeutic choice.
Adult ; Aged ; Antioxidants ; therapeutic use ; Colchicine ; therapeutic use ; Erectile Dysfunction ; diagnostic imaging ; drug therapy ; physiopathology ; Gout Suppressants ; therapeutic use ; Humans ; Male ; Middle Aged ; Penile Induration ; diagnostic imaging ; drug therapy ; physiopathology ; Penis ; blood supply ; pathology ; physiopathology ; Ultrasonography, Doppler, Color ; Vitamin E ; therapeutic use