1.Effects of two different reconstruction methods of digestive tract after radical total gastrectomy on quality of life and immune nutrition status in patients with gastric cancer
Tianzhu HE ; Qiang HU ; Lu ZHANG ; Yuanshui SUN
Chinese Journal of Clinical Nutrition 2019;27(3):167-172
Objective To compare the quality of life,nutritional status and immune function of gastric cancer patients with digestive tract reconstruction using Roux-en-Y anastomosis and uncut Roux-en-Y anastomosis after radical gastrectomy.Methods 86 patients with gastric cancer were selected from May 2015 to June 2017 with radical total gastrectomy.According to the different ways of the reconstruction of the digestive tract,the patients were divided into URY group (non-severed group,41 patients) and RY group (traditional group,45 patients).The quality of life of the two groups was compared at 1 month,3 months and 6 months after operation.The nutritional status of albumin,prealbumin,transferrin,hemoglobin,retinol binding protein and weight,as well as CD4+ lymphocyte,CD8+ lymphocyte,CD4+/CD8+ ratio,IgG,IgM,IgA and other immune related indexes were observed at pre-operation and 1 month,3 months and 6 months after operation.Results As for quality of life,the score of diet limitation in group URY was significantly lower than that in group RY at 1 month after operation (P<0.05),and no significant difference at 3 months and 6 months after operation (P>0.05);As for anxiety,the score of group URY was higher than that in group RY (P< 0.05) at 1 month after operation (P<0.05),and was lower than that in group RY at 3 months and 6 months after operation (P<0.05).As for dry mouth,group URY was higher than that in group RY (P<0.05) at 3 months and 6 months after operation (P<0.05),and the other indexes were not statistically significant (P> 0.05).As for the nutritional indexes,prealbumin in the URY group was higher than that in the RY group at 6 months after operation (P<0.05),and the rest were not statistically significant (P>0.05).There was no statistical significance in immune indexes between the two groups (P > 0.05).The postoperative hospitalization time of URY group was less than that of RY group (P<0.05),and the incidence of mild reflux symptoms was lower than that of RY group (P<0.05).There was no significant difference in the incidence of other complications between the two groups (P>0.05).Conclusion Except for the length of hospitalization and postoperative complications in which uncut Roux-en-Y anastomosis was superior to Roux-en-Y anastomosis,there is no significant difference in quality of life and nutritional and immune indicators between the two alimentary tract reconstruction methods.
2.The theoretical research on Yi He rehabilitation in staging treatment of post-stroke hemiplegia
Tianzhu CHEN ; Tianyan CHEN ; Yong ZHANG ; Kang WU ; He JIN ; Yihuai ZOU
Journal of Beijing University of Traditional Chinese Medicine 2024;47(1):24-29
Yi He Rehabilitation,which is based on traditional Chinese rehabilitation treatments and rehabilitation principles from modern medicine,is effective in staging treatment of post-stroke hemiplegia.This paper systematically discusses the origin and annotation of Yi and He from the perspectives of traditional Chinese medicine and modern medicine.The medicinal connection between Yi and the body and its function is related to unobstructed attunement.Based on the connotation of Yi and He,we believe that the pathogenesis of post-stroke hemiplegia is the comprehensive result of abnormal effects of Yi on the organism at the microscopic level and abnormal effects of He on function at the macroscopic level,featured as tense muscle movement and a pathological process of abnormal motion,including the disturbance of yang qi with body dysfunction,the disorder of spirit with sinews and vessels with diversion,and the variation of brain collateral with physical and mental inconsistency.By inducing relaxation and calmness,Yi He rehabilitation takes effect in staging treatment of post-stroke hemiplegia with characteristic mechanisms.First,by calming ascending yang and relaxing the disordered body in periods of relaxation,it can achieve the maintenance function of the kinematic chain peripherally with passive rehabilitation.Second,by calming the disordered spirit and relaxing the inhibited meridian sinews in spasmodic periods,it can reconstruct the neural plasticity of motor function centrally with assistive rehabilitation.Third,by calming damaged brain collateral and relaxing the impassable zang organs in the recovery period,it can close the central-peripheral-central loop of rehabilitation with active rehabilitation.