1.Graphical modeling of ICF Core Set (Comprehensive Version for Stroke)
Meng YOU ; Zhuqing JIANG ; Xu WANG ; Shengli DI ; Fengqin ZHANG ; Zhaoming GUO ; Jian XIANG ; Lin CHANG ; Tiantong YANG
Chinese Journal of Forensic Medicine 2016;31(4):336-340
Objective It aims to investigate the relationships among the categories of Comprehensive Version for Stroke as described in the International Classiifcation of Functioning, Disability and Health (ICF) Core Set, and to provide new supports for Judicial Appraisal of functioning in stroke by ICF functioning mapping.Methods The variables of 59 categories of ICF assessment scale and the samples of 106 persons’ are selected and used in the least absolute shrinkage and selection operator (LASSO) for mining dependencies among those variables. The graphical modeling and analyzing with the software Gephi provides a visual map of the correlations among those classiifcations. Results 59 interconnected categories which organized into the functioning mapping. b340, b735, b175 and b152 are centrally positioned categories because of their high correlation.Conclusion Functioning mapping by graphical modeling can reveal complex relational structures embedded in functioning classiifcations, which provides the support for using ICF to appraisal stroke.
2.Correlation between postmortem intervals and the changes of 18s rRNA degradation in liver after death under the ;condition of different temperature(
Zhuqing JIANG ; Dong ZHAO ; Haidong ZHANG ; Xu WANG ; Meng YOU ; Xi CHEN ; Xiaoxu ZHU ; Wei ZHONG ; Shi FENG ; Lin CHANG ; Tiantong YANG
Chinese Journal of Forensic Medicine 2016;31(5):441-443
Objective To investigate the relationship between Ct value of mice liver and postmortem interval (PMI) under various ambient temperatures. Methods mice were stored at 10℃, 15℃, 20℃, 25℃ and 30℃ after execution, and total RNA was extracted from mice liver every 6 hours (PMI 6h to 72h). The levels of 18s rRNA were examined using real-time PCR. The results were expressed by cycle threshold (Ct) value to explore relationship between PMI and Ct value, and the interpolation functions were established to estimate PMI. Results In each group, Ct value increased with PMI increased. Surface equation was obtained after interpolation analysis on temperature range 10℃~30℃. The three-variable quintic surface equation was f(x, y)=-426.9+30.82x+44.48y-1.297x2-1.837xy-1.388y2+0.034 38x3+0.038 17x2y+0.038 67xy2+0.028 77y3-0.000 612 9x4-3.897e-7x3y-0.001 223x2y2+0.000 256 6xy3-0.000 537 4y4+3.606e-6x5-2.846e-6x4y+1.009e-5x3y2-3.439e-6x2y3-2.556e-7xy4+2.664e-6y5(r2=0.999 4). Conclusion The rule of Ct value changes at ambient temperature complied with three-variable quintic surface equation distribution. Measurement of interpolation function may be used for PMI estimation at ambient temperature.
3.Exploring the Application of Auricular Concha Eletro-Acupuncture in Functional Dyspepsia from the"Ear-Brain-Liver-Spleen"Correlation
Yi LUO ; Yue MA ; Tiantong JIANG ; Chaoren TAN ; Yongsheng YANG ; Jiliang FANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2023;25(10):3407-3412
Based on the traditional medical theory,the theory of"ear-brain-liver-spleen correlation"was proposed by linking the ear with the brain,liver and spleen.Then,by combining the Chinese medical etiology of Functional Dyspepsia(FD)and the corresponding modern medical mechanism,we realized that the close connection between the ear,brain,liver and spleen is the theoretical basis for treating FD from the ear.In recent years,a new type of vagus nerve stimulation therapy,auricular concha eletro-acupuncture(ACEA),has been developed to treat FD by regulating the liver and spleen through the regulation of the brain,relieving liver depression and strengthening spleen and qi,thus treating FD.In terms of modern medicine,this is related to its ability to reduce anxiety and depression,reduce pain perception,enhance gastrointestinal motility and reduce central and peripheral inflammation by regulating the activity of the corresponding brain functional areas.By exploring the application of auricular concha eletro-acupuncture in FD on the basis of the"ear-brain-liver-spleen correlation",we will better understand the unique role of auricular stimulation in regulating the brain and the blood of the liver and spleen,and promote the inheritance,innovation and development of TCM theory.
4.A study on detection of α-helix protein in posttraumatic epileptogenic focus by FTIR-mapping
Siyang XIANG ; Zhuqing JIANG ; Jiangtao LI ; Meng YOU ; Haidong ZHANG ; Xu WANG ; Hongxia LIU ; Tiantong YANG
Chinese Journal of Forensic Medicine 2017;32(6):583-587
Objective The article is to study on the detection of α-helix proteins in post-traumatic epileptogenic focus by FTIR-mapping. Methods Fourier transform infrared spectroscopy-mapping were applied to identifying α-helix by point-by-point scanning in post-traumatic epileptogenic focus sections and to develop FTIR-mapping profiles. Result The high absorbance of α-helix is accord with post-traumatic epilepsy, there are some significant differences between high absorbance and low absorbance. Conclusion α-helix proteins are distributed in post-traumatic epileptogenic focus widely, thus α-helix protein are involved in post-traumatic epilepsy.
5.Spine and extremities impairment: comparative study on clause for Identification of the body injured and Classification of the body impairment
Siyang XIANG ; Lili YU ; Xu WANG ; Jian XIANG ; Meng YOU ; Zhuqing JIANG ; Tiantong YANG
Chinese Journal of Forensic Medicine 2017;32(5):518-521
The article is comparative study about spine and extremities on clause for the identification of the body injured and The classification of the body impairment. We reviewed the terms and provisions about spine and extremities as follows, amputation impairment, function impairment, and amputation impairment combined function impairment. This paper provides a comprehensive access and analysisofthe similarities and differences between the two standards.