Objective:To explore the application effect of hierarchical constraint management scheme in ICU patients.Methods:From March 2018 to February 2020, the convenient sampling was used to select 195 patients admitted to ICU of the First Affiliated Hospital of Air Force Medical University as the research objects. Patients admitted from March 2018 to February 2019 were set as the control group ( n=97) , and routine constraint management was implemented. Patients admitted from March 2019 to February 2020 were set as the observation group (n=98) , and hierarchical constraint management was implemented on the basis of the control group. The incidence of delirium, unplanned extubatino, and constraint-related complications were compared between the two groups. Results:The total incidences of unplanned extubation and constraint-related complications in the observation group were lower than those in the control group, and the differences were statistically significant ( P<0.05) . Conclusions:The application of hierarchical constraint management scheme in ICU patients can reduce the risk of unplanned extubation, which can provide reference for the nursing plan of risk management of unplanned extubation and constraining related complications in ICU patients.