Objective To investigate the effect of elemene on leptin, AFP and liver function of patients with advanced liver cancer.Methods 73 cases with advanced liver cancer of our hospital were selected and according to the random number table method were randomly assigned for two groups:control group (37 cases) were given routine clinical therapy;experimental group (36 cases) were treated on the basis of the control group with elemene injection.leptin, AFP ,CRP and liver function were compared after the treatment.ResuIts Compared with control group post-treatment, the leptin level in the experimental group was higher, CRP was lower(P<0.05); the serum level of AFP, CEA and CA199 were lower (P<0.05), the ALT, TBIL, AST, PT were lower ( P<0.05 ) , and the total effective rate was significantly higher ( P<0.05 ) .ConcIusion Elemene injection can improve liver function, elevate serum leptin level, reduce the levels of CRP, tumor marker levels and improve the quality of life .

Objective To investigate the influence factors of Cornell product and its clinical value in pa-tients with left ventricular high voltage.Methods 104 patients with left ventricular high voltage were studied and divided into two groups according to Cornell product:Cornell product normal group(n = 78)and Cornell product abnormal group(n=26). Clinical manifestations ,complicaions and ultracardiographic data in these patients were collected and analyzed. Results Chronic kidney disease(CKD)(OR=4.266,95%CI 1.276-14.257,P=0.018) and left ventricular mass index(LVMI)(OR = 1.023,95%CI 1.004-1.043,P = 0.016)were related to Cornell product. Cornell product was positively correlated LVMI appeared(r=0.497,P<0.001). The correlation of Cor-nell product with left ventricularend-diastolic dimension ,interventricular septal thickness and left ventricular poste-rior wall thickness was weak.ROC-AUC of Cornell product for CKD was 0.634,95%CI=0.506-0.780,P=0.039, sensibility 47.8%,and specificity 81.5%. Conclusions LVMI and CKD are independent influence factors of Cor-nell product. Cornell product has a certain diagnositc value for left ventricular hypertrophy ,but it has no associa-tion with the location of ventricular hypertrophy.