This paper discussed the pathogenesis and treatment ideas of recurrent angina pectoris after percutaneous coronary intervention (PCI) based on qi and blood vessels. It is believed that patients after PCI often have poor qi and blood circulation and damaged vessels and collaterals as the basis, and subsequently suffer from binding of phlegm and stasis, accumulated and sticky, which further lead to the vessels congested and blocked, qi and blood declined, and the body and functions of the heart damaged. Accordingly, in terms of the treatment principles, it has been proposed to regulate qi and transport blood, unblock and nourish vessels, dissolve phlegm and dispel stasis, direct turbidity downward and unblock collaterals, supplement qi and nourish the body, unblock vessels and rejuvenate meridians, by using self-made Tiaoqi Yunxue Formula (调气运血方), self-made Huoxue Jiangzhuo Formula (活血降浊方) and self-made Shenrong Tongmai Formula (参茸通脉方) in their modifications respectively, in order to provide reference for clinical diagnosis and treatment.