OBJECTIVE To varify the difference of serum specific IgE levels in different ages and gender inpatients with Aspergillus fumigatus or Alternaria alternate induced allergic rhinitis. METHODS In this study, 85 patients with Aspergillus fumigatus or Alternaria alternate induced allergic rhinitis were included. sIgE tests was done by Immuno CAP 250TM System(Thermo Fisher Scientific, Uppsala, Sweden). RESULTS Mean level of aspergillus fumigatus sIgE was significantly lower than Alternaria alternate(P<0.05), single or dual fungi allergy show no impact on this difference. sIgE level showed positive correlation with age in Aspergillus fumigatus group(P <0.05), while negative in Alternaria alternate group(P <0.05). CONCLUSION Aspergillus fumigatus and Alternaria alternate are mostly common fungi allergens, sIgE detection of those two fungi are important for diagnosis of fungi induced allergic rhinitis and other respiratory diseases in people with different ages.

Allergen testing for the diagnosis and treatment of allergic diseases is essential , with the development of detection technology , automatic quantitative detection technology has become an important means of allergen detection and development trend .Compared with qualitative test , quantitative test can be more accurate in the diagnosis of allergic diseases , and can more effectively reflect the incidence of allergy , predict the occurrence and prognosis of the disease , and monitor the treatment effect.Therefore, although there are still many challenges in the quantitative detection of allergens , the automatic quantification of allergen detection is still an inevitable trend .

Humans ; Physicians ; economics