1.Clinical research of recombinant human acidic fibroblast growth factor in cesarean section women abdominal incision healing
Haijuan ZHANG ; Tian TIAN ; Yanjun CHEN
Chinese Journal of Postgraduates of Medicine 2014;37(24):43-46
Objective To evaluate the recent impact and long-term effects of recombinant human acidic fibroblast growth factor (rh-aFGF) of cesarean section on women's abdominal incision healing.Methods In 516 cases of cesarean section in women,randomly divided into placebo group (172 cases),spray group (172 cases) and flush group (172 cases).The placebo group received 0.9% sodium chloride washing abdominal incision suture.The spray group incision suture direcdy after the administration of rh-aFGF spray,per square meter of 3-4 sprays,3-5 times/d.The flush group was given before 2 rh-aFGF dissolved in 10-20 ml of 0.9% sodium chloride directly after washing the incision suture,then given spray treatment.The recent follow-up of 15 d observed maternal abdominal incision healing.Long term follow-up of 3 months to observe the incision scar formation.Results The abdominal incision heating time was (8.6 ±3.5) d,that was obviously shorter than that in spray group (10.4 ±3.7) d and placebo group (12.7 ± 4.9) d (P < 0.05).The delay healing accounted for 4.2% (7/166) in flush group,significantly lower than that in placebo group (34/168,20.2%) and spray group (16/165,9.7%) (P< 0.05).There was no significant difference in the incidence of fat liquefaction,postoperative infection among three groups (P > 0.05).Flush group exudation,abdominal wall adhesions was lower than placebo group and spray group [2.4%(4/166) vs.10.1%(17/168),5.5%(9/165),3.6%(6/166) vs.17.3%(29/168),9.7%(16/165)](P<0.05).Long term follow-up,flush group scar area than spray group reduced by 13.5%,than placebo group reduced by 27.2%.Conclusions A recent rh-aFGF can reduce the cesarean section abdominal incision healing time and reduce abdominal wall adhesions and exudation;rh-aFGF the best dosage is intraoperative irrigation treatment spray combined with postoperative.
2.Effect of Niaochangshu Capsule on Urodynamics of Patients with Post-menopause Urethral Syndrome
Yonghua ZHANG ; Ying TIAN ; Dali TIAN
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(09):-
Objective To investigate the effect of Niaochangshu capsule on urodynamics in bladder filling period of patients with post-menopause urethral syndrome of renal deficiency and blood stasis type.Methods A total of 36 patients with post-menopause urethral syndrome of renal deficiency and blood stasis type were randomly assigned to two groups:the trial group(24 patients were treated with Niaochangshu capsule) and the control group(12 patients were treated with Nilestriol).All patients were treated for 8 weeks.The changes of the urodynamic indexes in bladder filling period(the capacity of the bladder,the compliance of the bladder and the sensitivity of the bladder) were compared between the two groups.Results After treatment,the urodynamic index,including the maximum cystic capacity,the volume at the first desire to void and the cystic compliance were evidently improved in both of the trial group and the control group(P0.05).Conclusion Niaochangshu capsule is effective in treating the patients with post-menopause urethral syndrome of renal deficiency and blood stasis type.It can increase the cystic capacity and compliance,step down the sensitivity of the bladder.Its effect is similar to Nilestriol.
3.An evaluation scale of medical services quality based on "patients' experience".
Chang-Jun, TIAN ; Yue, TIAN ; Liang, ZHANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2014;34(2):289-97
An evaluation scale of medical services quality was developed on the basis of "patients' experience". The questionnaires were developed by, among others, searching relevant literature, collecting well-established assessment scales, measuring patients' experience and satisfaction, brain-storming, literature analysis. Delphi method was adopted for expert consultation. Scale items were screened and revised. The key indexes were converted. Field surveys were conducted for testing the reliability and validity of the scale. Our modified evaluation scale for measuring medical services quality based on "patients' experience" included 6 dimensions (tangibility, reliability, responsiveness, assurance, empathy and continuity), and 50 items. The novel scale based on "patients' experience" may better serve the purpose of assessing medical services quality.
4.Clinical efficacy and safety analysis of left colon and intestinal surgery phase I and phase II
Chinese Journal of Primary Medicine and Pharmacy 2014;(22):3394-3395
Objective To analyze clinical efficacy and safety of left colon and bowel obstruction .Methods 80 cases of left colon and bowel obstruction were divided into the observation group and control group,40 cases in each group.The observation group was given a surgery,and the control group received two surgical treatment,the two groups were taken the statistical analysis of clinical data to compare the clinical efficacy and safety of operation. Results The operative time,hospital stay and surgical blood loss in the observation group was (42.9 ±13.8) min, (9.3 ±2.8)d,(45.9 ±11.7)mL,which in the control group were (58.6 ±17.6)min,(6.8 ±1.5)d,(151.4 ± 19.4)mL,there were statistically significant difference between the two groups(t=25.358,16.128,29.475,all P<0.05);The abdominal abscess,lung infections and wound infection incidence of adverse reactions in the observation group was 7.5 %,10.0%,20.0 %,which in the control group was 17.5 %,2.5%,10.0%,there were statistically significant difference between the two groups (t=4.512,4.336,4.762,all P<0.05).Conclusion The clinical treatment of left colon and bowel obstruction shall promptly conduct a surgery,the role of hospitalization in patients with shorter length to enhance tumor resection rate,and actively improve the quality of life of patients.
5.Research progress on prostate biopsy and positive predicting factors
International Journal of Surgery 2017;44(3):207-211
New method of prostate cancer has grown more precise with the development of medical imaging.Multi-parametric MRI targeted biopsy and fusion biopsy reduce the cores,at the same time they have similar positive rates compared to systematic biopsy.The most used biopsy methods are still transrectal guided transrectal biopsy and transperineal biopsy in China.If we can predict biopsy result before the operation by physical and laboratory examination,it will help improve the detection rate and avoid repeating biopsies.And it has been indicated that age,tPSA,PSAD,fPSA/tPSA,PV,DRE,PHI and PCA3 are the predicting factors.Chinese Prostate Cancer Consortium Risk Calculator is fit for Chinses people.
6.Analysis on Medication of TCM Decoction Pieces for Reinforcing Deficiency in The First Affiliated Hospital of Xi'an Jiaotong University from 2013 to 2015
Chinese Journal of Information on Traditional Chinese Medicine 2017;24(4):120-122
Objective To analyze the clinical utility of TCM decoction pieces for reinforcing deficiency in the First Affiliated Hospital of Xi'an Jiaotong University (hereinafter referred to as our hospital).Methods By using Microsoft Office Excel 2013 software, use frequency, classifications of pharmacological actions and doses of the TCM decoction pieces for reinforcing deficiency from 2013 to 2015 were analyzed.Results From 2013 to 2015, some TCM decoction pieces for reinforcing deficiency showed relatively high use frequency in our hospital (>30%). In top 15 TCM decoction pieces for reinforcing deficiency, the amounts of medicine for tonifying qi were more than 40%, whose average doses exceeded the upper limit of pharmacopoeia dosage reaching 30%. The total over-use rate of TCM decoction pieces for reinforcing deficiency>50% and the not exceeded part accounted for 36.0%.Conclusion It is suggested that the use of TCM decoction pieces should be careful differentiation of symptoms, and the dose should also meet the specifications.
7.Evaluation and reference of foreign medical college teacher teaching competency standards
Chinese Journal of Medical Education Research 2015;14(4):330-333
Currently our medical colleges have no uniform competency standards for teachers teaching,and the assessment of teaching ability is vaguely defined.Through the content and effect analysis of foreign teaching competency standards assessment,according to the particularity of medical colleges,and by carding several aspects of the teacher ability content system,the author of the article put forward recommendations of building our medical colleges teacher teaching competency standards and improve medical colleges teachers' teaching ability and level.
8.Inborn errors of metabolism and epilepsy in children
Chinese Journal of Applied Clinical Pediatrics 2015;30(12):881-884
Epilepsy is a common disorder of neurological system in children.Inborn errors of metabolism (IEMs) is one of an important etiology of epilepsy.Seizures may be the first and the major presenting feature of IEMs.IEMs are a relatively rare cause of epilepsy,but their recognition and diagnosis is very important because several disorders are treatable.This review will concentrate on diseases where epilepsy is the predominant clinical manifestation and especially where the disease course can be positively influenced by specific metabolic therapies.
9.Effect of ademetionine assisted therapy on serum transferrin, myocardial enzyme spectrum and bilirubin in icterus neonatorum
Chinese Journal of Biochemical Pharmaceutics 2015;(8):66-68
Objective To investigate the effect of ademetionine assisted therapy on transferrin ( TRF) , myocardial enzyme spectrum and bilirubin in serum of patients with icterus neonatorum.Methods 86 cases of neonatal jaundice in the hospital were randomly divided into two groups.43 cases in control group were treated with conventional therapy, 43 cases in experimental group were treated by ademetionine.Serum transferrin, myocardial enzymes, serum total bilirubin levels and clinical effects were compared pre-treatment and post-weat ment.ResuIts Compared with control group, the TRF level of experimental group was higher (P<0.05), the level of Aspartate transaminase (AST), lactate dehydrogenase (LDH), creatine kinase (CK), and CK-MB in experimental group were lower (P<0.05), the total bile acid (TBA), total bilirubin (TBIL) and direct bilirubin (DBIL) in experimental group were lower (P<0.05).The total effective rate in experimental group was significantly higher than that in control group (χ2 =8.53, P<0.05).ConcIusion Ademetionine assisted therapy has a good clinical curative effect and could effectively reduce serum TRF, DBIL and myocardial enzyme spectrum level, which has important significance in the treatment of neonatal jaundice.
10.Spatial distributions of multi-channel electroencephalographs power in different frequency band during visual working memory
International Journal of Biomedical Engineering 2015;38(2):77-80
Objective Working memory (WM) is one of important cognitive functions.The aim of this study was to investigate spatial distributions of electroencephalographs (EEGs) power during visual WM task,which may provide support for studying the principal frequency band and critical region related to WM.Methods 32-channel EEGs were recorded from 16 healthy subjects while they perform visual WM task.The data came from 240 trials and the original EEGs were preprocessed.Fourier transform was applied to calculate spatial distributions of EEGs power in the δ,θ,α,β,γfrequency bands and the percentage of each band in the total power.Results The percentages of δ,θ,α,β,γbands in the total power were (22.44±0.86)%,(31.88±0.55)%,(24.66±1.43)%,(13.54±0.64)%,(7.47±0.48)%,respectively.The power in the θ band was significantly higher than those in the other bands (paired t-test,P<0.001).The θ power was focused in the frontal midline region.Conclusions The principal frequency band related to WM was the θ band and the critical region was the frontal region.