1.Effect of Niaochangshu Capsule on Urodynamics of Patients with Post-menopause Urethral Syndrome
Yonghua ZHANG ; Ying TIAN ; Dali TIAN
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(09):-
Objective To investigate the effect of Niaochangshu capsule on urodynamics in bladder filling period of patients with post-menopause urethral syndrome of renal deficiency and blood stasis type.Methods A total of 36 patients with post-menopause urethral syndrome of renal deficiency and blood stasis type were randomly assigned to two groups:the trial group(24 patients were treated with Niaochangshu capsule) and the control group(12 patients were treated with Nilestriol).All patients were treated for 8 weeks.The changes of the urodynamic indexes in bladder filling period(the capacity of the bladder,the compliance of the bladder and the sensitivity of the bladder) were compared between the two groups.Results After treatment,the urodynamic index,including the maximum cystic capacity,the volume at the first desire to void and the cystic compliance were evidently improved in both of the trial group and the control group(P0.05).Conclusion Niaochangshu capsule is effective in treating the patients with post-menopause urethral syndrome of renal deficiency and blood stasis type.It can increase the cystic capacity and compliance,step down the sensitivity of the bladder.Its effect is similar to Nilestriol.
2.Clinical research of recombinant human acidic fibroblast growth factor in cesarean section women abdominal incision healing
Haijuan ZHANG ; Tian TIAN ; Yanjun CHEN
Chinese Journal of Postgraduates of Medicine 2014;37(24):43-46
Objective To evaluate the recent impact and long-term effects of recombinant human acidic fibroblast growth factor (rh-aFGF) of cesarean section on women's abdominal incision healing.Methods In 516 cases of cesarean section in women,randomly divided into placebo group (172 cases),spray group (172 cases) and flush group (172 cases).The placebo group received 0.9% sodium chloride washing abdominal incision suture.The spray group incision suture direcdy after the administration of rh-aFGF spray,per square meter of 3-4 sprays,3-5 times/d.The flush group was given before 2 rh-aFGF dissolved in 10-20 ml of 0.9% sodium chloride directly after washing the incision suture,then given spray treatment.The recent follow-up of 15 d observed maternal abdominal incision healing.Long term follow-up of 3 months to observe the incision scar formation.Results The abdominal incision heating time was (8.6 ±3.5) d,that was obviously shorter than that in spray group (10.4 ±3.7) d and placebo group (12.7 ± 4.9) d (P < 0.05).The delay healing accounted for 4.2% (7/166) in flush group,significantly lower than that in placebo group (34/168,20.2%) and spray group (16/165,9.7%) (P< 0.05).There was no significant difference in the incidence of fat liquefaction,postoperative infection among three groups (P > 0.05).Flush group exudation,abdominal wall adhesions was lower than placebo group and spray group [2.4%(4/166) vs.10.1%(17/168),5.5%(9/165),3.6%(6/166) vs.17.3%(29/168),9.7%(16/165)](P<0.05).Long term follow-up,flush group scar area than spray group reduced by 13.5%,than placebo group reduced by 27.2%.Conclusions A recent rh-aFGF can reduce the cesarean section abdominal incision healing time and reduce abdominal wall adhesions and exudation;rh-aFGF the best dosage is intraoperative irrigation treatment spray combined with postoperative.
3.An evaluation scale of medical services quality based on "patients' experience".
Chang-Jun, TIAN ; Yue, TIAN ; Liang, ZHANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2014;34(2):289-97
An evaluation scale of medical services quality was developed on the basis of "patients' experience". The questionnaires were developed by, among others, searching relevant literature, collecting well-established assessment scales, measuring patients' experience and satisfaction, brain-storming, literature analysis. Delphi method was adopted for expert consultation. Scale items were screened and revised. The key indexes were converted. Field surveys were conducted for testing the reliability and validity of the scale. Our modified evaluation scale for measuring medical services quality based on "patients' experience" included 6 dimensions (tangibility, reliability, responsiveness, assurance, empathy and continuity), and 50 items. The novel scale based on "patients' experience" may better serve the purpose of assessing medical services quality.
4.Analysis of Expression of Multidrug Resistance Gene and Multidrug Resistance-Associated Protein Gene in Patients with Non-small-cell Lung Cancer
Tianjin Medical Journal 2000;28(12):738-739
Objective:To investigate the expression of multidrug resistance (MDR1) gene and multidrug resistance-associated pro-tein (MRP) gene in patients with non-small-cell lung cancer (NSCLC) and its relation to histopathological type. Methods:The MDRi and MRP genes were determined by reverse transcription-polymerase chain reaction (RT-PCR) in 48 NSCLCspecimens. Results:The positive rates of the MDR1 and MRP gene expression were 62.5% and 66.7% respectively in the48 patients. Twenty-one of the 48 NSCLCs (43.8%) expressed both MDR1 and MRP genes. The positive rates of the MRPgene expression in squamous cell carcinoma was significantly higher than those in adenocarcinoma (P<0.01), and therewas no significant difference in MDR1 gene expression between the two groups (P>0.05). Conclusion: The MDR1 andMRP gene expressions were both or respectively in the NSCLCs. The incidence of the MRP gene expression in squamous cellcarcinoma was higher than that in adenocarcinoma.
5.Effect of ademetionine assisted therapy on serum transferrin, myocardial enzyme spectrum and bilirubin in icterus neonatorum
Chinese Journal of Biochemical Pharmaceutics 2015;(8):66-68
Objective To investigate the effect of ademetionine assisted therapy on transferrin ( TRF) , myocardial enzyme spectrum and bilirubin in serum of patients with icterus neonatorum.Methods 86 cases of neonatal jaundice in the hospital were randomly divided into two groups.43 cases in control group were treated with conventional therapy, 43 cases in experimental group were treated by ademetionine.Serum transferrin, myocardial enzymes, serum total bilirubin levels and clinical effects were compared pre-treatment and post-weat ment.ResuIts Compared with control group, the TRF level of experimental group was higher (P<0.05), the level of Aspartate transaminase (AST), lactate dehydrogenase (LDH), creatine kinase (CK), and CK-MB in experimental group were lower (P<0.05), the total bile acid (TBA), total bilirubin (TBIL) and direct bilirubin (DBIL) in experimental group were lower (P<0.05).The total effective rate in experimental group was significantly higher than that in control group (χ2 =8.53, P<0.05).ConcIusion Ademetionine assisted therapy has a good clinical curative effect and could effectively reduce serum TRF, DBIL and myocardial enzyme spectrum level, which has important significance in the treatment of neonatal jaundice.
6.Effects of note-taking habits on academic scores of junior middle school students
Chinese Journal of Behavioral Medicine and Brain Science 2009;18(10):941-943
Objective To examine the impact of note-taking habits on academic scores of junior middle school students.Methods A sample of 412 junior middle school students were applied a self-developed note-taking habits inventory (NTHI) ,and the impact of note-taking habits on academic scores was examined by using bivariate correlation and linear regression analysis.Results Girls got significantly higher NTHI scores than boys [(3.67±0.55)vs(3.19±0.80),P<0.01] ,and students from key classes got significantly higher NTHI scores than those of typical classes[(3.56±0.64)vs (3.37±0.75),P< 0.05].Total academic scores of Chinese,mathmatics and English was found significantly and positively related to total NTHI scores and the five subscales(r=0.280,P<0.01 ;r=0.293,P< 0.01 ;r=0.126,P<0.05 ;r=0.255,P<0.01 ;r=0.239,P<0.01 ;r=0.280,P < 0.01).Attitude towards note-taking,full note-making and immediate note-rewriting showed direct and significant influence on total academic score of Chinese,mathmatics and English.Full note-making,attitude towards notetaking and immediate note-rewriting showed direct and significant influence on score of Chinese.So did of active note-making,immediate note-rewriting,full note-making and attitude towards note-taking on mathmatice scores,attitude towards note-taking and full note-making on score of Chinese.Conclusion Note-taking habits could be direct predictor of their academic scores for junior middle school students.
7.Application of MTT Colorimetric Assay in Research of Cytokine Activity and Cytotoxicity of Killer Cells
Chinese Journal of Cancer Biotherapy 1994;0(01):-
We used MTT assay to test the cellular cytotoxicity ( NK, LAK, CTL, Macrophage), cytokine activities ( 1L-1, 1L-2, 1L-6, TNF), proliferation of lymphocytes and chemosensitivity of tumor cells, and compared it with radioactive isotope assay. The results showed that the MTT assay may be used to test the cellular cytotoxicity, cytokine ac-tivity, proliferation of lymphocytes and chemosensitivity of tumor cells. We think it is a simple, rapid, economic and safety method.
8.Comparative study on laparoscopy assisted radio frequency ablation and percutaneous radio frequency ablation for hepatocellular carcinoma
Chinese Journal of General Surgery 2012;27(7):564-567
Objective To evaluate laparoscopy assisted radio frequency ablation (LRFA) and percutaneous radiofrequency ablation ( PRFA ) for the treatment of hepatocellular carcinoma ( HCC ).Methods A total of 525 HCC patients were enrolled,including LRFA group of 78 cases with 106 tumor nodules,and PRFA group of 447 cases with 565 tumor nodules.Results ( 1 ) In LRFA group complete ablation rate was 97.17% (103/106); in LRFA group complete ablation rate was 93.09% (526/565)(x2 =2.523,P =0.112).(2)The 1,3,5 year overall survival rate was 96.15%,55.12% and 38.46%in LRFA group and 93.73%,48.54% and 31.54% in PRFA group respectively ( x2 =0.699,1.151,1.447 ; P =0.403,0.283,0.229 ).The 1,3,5 year disease-free survival rate was 94.87%,43.58% and 28.21% in LRFA group and 93.73%,48.54% and 31.54% in PRFA group respectively (x2 =0.915,0.303,0.174; P=0.339,0.582,0.676).The average disease-free survival time was 22.25 months in LRFA group and 21.53 months in PRFA group respectively.(3)The serious complications was 0% (0/78)in LRFA group and 1.34% ( 6/447 ) in PRFA group respectively.( 4 ) Recurrence rate was 23.07%(18/78) in LRFA group,and 34.89% (156/447) in PRFA group ( x2 =4.189,P =0.041 ).Conclusions The therapeutical effect of LRFA equals that of PRFA,while enjoying lower recurrence rate,no serious complications and higher treatment safety.
9.Clinical efficacy and safety analysis of left colon and intestinal surgery phase I and phase II
Chinese Journal of Primary Medicine and Pharmacy 2014;(22):3394-3395
Objective To analyze clinical efficacy and safety of left colon and bowel obstruction .Methods 80 cases of left colon and bowel obstruction were divided into the observation group and control group,40 cases in each group.The observation group was given a surgery,and the control group received two surgical treatment,the two groups were taken the statistical analysis of clinical data to compare the clinical efficacy and safety of operation. Results The operative time,hospital stay and surgical blood loss in the observation group was (42.9 ±13.8) min, (9.3 ±2.8)d,(45.9 ±11.7)mL,which in the control group were (58.6 ±17.6)min,(6.8 ±1.5)d,(151.4 ± 19.4)mL,there were statistically significant difference between the two groups(t=25.358,16.128,29.475,all P<0.05);The abdominal abscess,lung infections and wound infection incidence of adverse reactions in the observation group was 7.5 %,10.0%,20.0 %,which in the control group was 17.5 %,2.5%,10.0%,there were statistically significant difference between the two groups (t=4.512,4.336,4.762,all P<0.05).Conclusion The clinical treatment of left colon and bowel obstruction shall promptly conduct a surgery,the role of hospitalization in patients with shorter length to enhance tumor resection rate,and actively improve the quality of life of patients.
10.Patient experience based key indicators for quality of care
Chinese Journal of Hospital Administration 2013;29(4):291-295
Objective To establish patient-experience based key indicators for quality of care.Methods Literature review,collection of proven surveys on patient experience and satisfaction,study of China's conditions,with demonstrations by experts team.Results A framework was built for patientexperience based key indicators on quality of care.Level-1 indicators within the framework are tangibility,reliability,responsiveness,assurance,care and continuity.There are 28 level-2 indicators and 83level-3 indicators.Conclusion Such key indicators are highly practical as the basis for developing the scale of patient experience.