AIM: Based on the principle of ergonomics theory, to propose the hypothesis of rehabilitation medicine to promote standardization of rehabilitation medicine. METHODS: Through survey, observation, and experiment, human physiological and psychological factors were analyzed. Scientific ergonomics design, planning, and management were used to enhance the clinical value of rehabilitation medicine efficacy in evidence-based medicine. RESULTS: Ergonomics-based rehabilitation can resolve common defects in rehabilitation clinical work and management, and promote the standardization of medical rehabilitation objectively and scientifically. CONCLUSION: Ergonomics-based rehabilitation medicine is more objective, scientific and practical, and the repeatability of rehabilitation treatment is improved. It is worth further clinical study.

Objective To investigate the altered lipid in systemic sclerosis(SSc),and the relationship between the altered lipid and inflammation.Methods A total of 58 SSc patients were recruited into SSc group,and 58 healthy persons were recruited into control group from 2012 to 2014.Triglyceride(TG),total cholesterol(TC),low density lipoprotein-cholesterol(LDL-c)and high density lipoprotein-cholesterol(HDL-c),lipoprotein a[LP(a)],C-reactive protein(CRP)and erythrocyte sedimentation rate(ESR) were assessed using standard techniques in all cases,antinuclear antibody(ANA)and anti-Scl-70 antibody were assessed only in SSc patients.The levels of lipids between SSc patients and healthy controls,patients with antibody and patients without antibody were compared by using t test,corrections between lipid and inflammation were analyzed by Spearman′s correlation test.Results The clinical manifestations of SSc were mostly Raynaud′s phenomenon(91.4%),large area of black hard shin(87.9%),gastrointestinal manifestations(75.9%).The rates of an increased level of TG and decreased level of HDL-c were 29.3%,89.7% respectively.The level of TG in SSc was significant higher than in healthy controls(P =0.021),and the level of HDL-c in SSc was significant lower than in healthy controls(P =0.033).The levels of lipids in patients with ANA and anti-Scl-70 antibody had no significant difference with the patients without ANA and anti-Scl-70 antibody (P >0.05 ).Spearman′s correlation test demonstrated that HDL-c level correlated negatively with serum CRP (r=-0.285,P =0.039)and ESR (r =-0.271,P =0.043)in SSc.Conclusion Dyslipi-demia is a common feature in SSc patients that are characterized by an increase in TG and a decrease in HDL-c,inflammation might partly account for the changes.

In this article , the hot ethical concerns related to totally endoscopic thyroidectomy have been ana-lyzed and discussed .The author considers that this procedure is consisted with the patient′s no-harm and advanta-geous ethical principles , and the patient′s privacy is well protected .However , different procedures and operative risks should be well understood by the patients before the operation .Patient′s independence should be respected .

Objective To investigate the comparability of test seven tumor marks results of two electrochemiluminescence immu-noassay analyzer between Roche Cobas E411 and Cobas E601 .Methods According to United States Clinical and Laboratory Stand-ards Institute (CLSI) EP9-A2 document ,E411 was acted as comparison method (X) and E601 was as the experimental method (Y ) .Alpha fetoprotein (AFP ) ,carcinoembryonic antigen (CEA ) ,carbohydrate antigen125 (CA125 ) ,carbohydrate antigen199 (CA199) ,carbohydrate antigen153(CA153) ,total prostate specific antigen(TPSA) and free prostate specific antigen(FPSA) levels of patient samples were tested and the results were analyzed .Results The correlation between the two systems was good and the bias was acceptable in the medical decision level .Conclusion Two systems have good concordance in detecting the seven tumor markers ,w hich can meet the clinical need .

Large scale preparation of human IL-2 mRNA was obtained from human spleen cells stimulated with PHA+TPA at the peak of IL-2 mRNA transcription. Full length of IL-2 mRNA was translated in wheat germ extract to produce bioactive IL-2 (tIL-2). The IL-2 mRNA was about 14 S depending on the 7 M Urea-SDS-PAGE, and recovried from gel and translated in vitro. The elute curve of tIL-2 was the same as that of recombinant IL-2 (rIL-2) and natural IL-2 (nIL-2), the molecular weight of tIL-2 was about 14.000 dalton. The translational process of IL-2 mRNA in vitro was inhibited when RNA was cultured with RNase or translated product was cultured with proteinase, proving a standard in-vitro translation.

Objective To study the correlation between MRI features and pathology of intraspinal neruilemmoma.Methods MRIfeatures of intraspinal neurilemmomas proved by operation and pathology in 16 cases were analysed retrospectively and in comparison with the results of pathology.Results All the tumors were intradural-extramedullary in location,including 6 in the cervical regions,5 in the upper thoracic regions,3 in the thoracic-lumbar junction and 2 in the lumbar regions.On MRI,the tumors were marginate elliptical heterogeneousisointense or slightly low intense with punctate or patchy more low intensity areas on T_1WI and heterogeneous slightly high intense orisointense with punctate or patchy more high intensity areas on T_2WI.Parts of the masses obviously enhanced with no enhancement of more low intensity areas on T_1WI.All of above imaging manifestations were corresponding to pathology of intraspinal neurilemmomas.Interlace of Antoni A and Antoni B was attributed to heterogeneous intensity.Antoni B that was no obviously enhancement was concentrated in bleeding and cystic areas and Antoni A that was obviously enhancement was concentrated in cellular area and collagen.Conclusion The imaging manifestations of intraspinal neurilemmoma is due to its varied pathologic changes,and this has guiding significance to the correct diagnosis.

Electret filtration material is a kind of promising new air filtration material due to the advantages of high filtration efficiency,low flow resistance,power saving and anti-bacteria.In the paper the concept of electret,primary raw material of electret filtration material,the characteristics of electret filter material,charging method to make electret and the influence of charging technology on the charge storage characteristic of electret filter material were introduced,the application of electret filtration material on air purification was described also.

Under stimulation of PHA,PHA + TPA,or PHA + PTS the time ke-netics of DNA,RNA,protein synthesis and lymphokine secretion by human lymph node cell expressed different responses. The PTS did not increase the DNA and RNA synthesis, but increased the protein synthesis ( 60% ) . TPA increased the RNA synthesis ( 18% ) , therefor increased the protein synthesis ( 40% ) . Both of TPA and PTS increased the production of 5 kinds of lymphokines (IL-1 , IL-2 , IL-3, BCGF, TFNr). We infer that PTS and TPA increase the lymphokine production through different gene regulation. TPA Promotes the translation of lymphokine mRNA。

Promoting effect of panaxatriol ginsenoside ( PTGS ) on inter-leukine-3(IL-3 ) induction of phyto-hemagglutinin ( PHA ) stimulated human lymph node cells was observed. The results showed that PTGS enhanced the IL-3 production on each time of IL-3-induction kinetics, maximally by 30% ( 72h ) . Furthermore, it was observed that IL-3 mRNA from PHA+PTGS-stimulated lymph node cells translated more IL-3 than PHA-stimulated lymph node cells on each time of IL-3 mRNA-induction kinetics, maximally by 40% ( 60h ) , using the methods of wheat germ cell-free in vitro translation system and IL-3 bioassay.

OBJECTIVE:To determine the content of epirubicin in human plasma by RP-HPLC.METHODS:The chromatographic separation was performed on YWG C18 column.The mobile phase consisted of water-acetonitrile(12∶7,with pH adjusted to 3.90?0.05 using 85% phosophoric acid)at a flow rate of 1.0 mL?min-1.The detective wavelength was set at 254 nm.RESULTS:The linear range of epirubicin was 0.12～4.80 mg?L-1(r=0.998 4)with the lowest detective range of 0.01 mg?L-1.The intraday RSD was less than 4.40% and the inter-day RSD was less than 5.60%,and the average recovery rate was 99.40%(RSD=4.02%).The sample solution was stable within 12 h under room temperature.CONCLUSION:The method is easy,precise and reproducible to operate and the result of the determination is accurate.