7.Incidence of Malignancy within Cytologically Indeterminate Thyroid Nodules.
Dong Il CHOI ; Yun Su YANG ; Sang Soo SO ; Eun Jung LEE ; Ki Hwan HONG
Korean Journal of Otolaryngology - Head and Neck Surgery 2006;49(11):1096-1100
BACKGROUND AND OBJECTIVES : The optimal management of cytologically indeterminate thyroid nodules is controversial given the variable malignancy rates reported in this patient population. We examined the prevalence of malignancy within cytologically indeterminate atypical and follicular thyroid lesions in an attempt to predict malignancy based on cytologic features. Subjects and METHOD : Cytopathologic reports obtained after fine-needle aspiration biopsy (FNAB) examination of indeterminate follicular thyroid lesions were studied over a 2-year period. The prevalence of malignancy on final pathology was determined in 2 indeterminate cytopathologic categories. RESULTS : A total of 138 records were available (122 women, 16 men). The mean patient age was 45.5+/-13.5 years. All patients underwent surgery and had histopathologic diagnosis. The prevalence of malignancy in atypical and follicular thyroid lesions were 77.7% (42 of 54) and 17.8% (15 of 84), respectively. CONCLUSION : The high prevalence of malignancy within indeterminate atypical and follicular thyroid lesions may necessitate thyroidectomy for patients with indeterminate atypical and follicular lesions on the FNAB examination.
Biopsy, Fine-Needle
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Diagnosis
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Female
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Humans
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Incidence*
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Pathology
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Prevalence
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Thyroid Gland*
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Thyroid Neoplasms
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Thyroid Nodule*
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Thyroidectomy
8.Thyroid clear cell carcinoma: a case report.
Jing LIANG ; Su-sheng SHI ; Wei LUO ; Fu-sheng LIU
Chinese Journal of Oncology 2005;27(5):295-295
9.Advances in primary thyroid lymphoma.
Yuan LI ; Ding-rong ZHONG ; Quan-cai CUI
Acta Academiae Medicinae Sinicae 2006;28(5):724-729
Primary thyroid lymphomas (PTLs) are closely correlated with the autoimmune reaction of thyroid. However, the molecular mechanisms of PTLs are still unclear. It is really necessary to improve the ability to differentiate between benign and malignant PTLs along with the introduction of some new molecular biology methods. The diagnosis and prognosis of PTLs depend on their histological features, pathological classification, and clinical stages. Customized therapy of PTLs becomes possible with the further advances in lymphoma's pathological classification, clinical stages, and international prognosis index standard.
Humans
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Lymphoma
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diagnosis
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pathology
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therapy
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Thyroid Neoplasms
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diagnosis
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pathology
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therapy
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