2.Papillary carcinoma in a thyroglossal duct remnant: a case report.
Jiao ZHOU ; Qiongling HUANG ; Ming LU ; Shuqiang CHU ; Yizheng ZHANG ; Chaohui ZHENG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2023;37(6):491-493
This case report has described a case of papillary carcinoma of thyroglossal duct in a young male. This patient was admitted with a mass in the anterior neck for 2 years. Preoperative Bultrasonography, CT and MR showed a subcutaneous cystic mass with irregular calcification shadow in the central region of the neck without obvious enhancement. Initial diagnosis was thyroglossal duct cyst, and was excised by Sistrunk under general anesthesia. The postoperative pathological examination showed thyroglossal duct cyst combined with thyroid papillary carcinoma, which was confirmed by immunohistochemistry as thyroglossal duct papillary carcinoma.
Humans
;
Male
;
Thyroid Neoplasms/surgery*
;
Carcinoma, Papillary/pathology*
;
Thyroglossal Cyst/surgery*
;
Thyroid Cancer, Papillary
3.Treatment experience of neck tumor surgeries involving carotid artery.
Zinian WANG ; Jingzhe LI ; Yuqi HE ; Tao YU ; Zhongliang ZHANG ; Qi KANG ; Fei GONG ; Yang XIA ; Shanshan XU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2023;37(7):570-574
Objective:To investigate surgical treatment of carotid artery diseases in neck tumor surgery. Methods:A retrospective analysis of the clinical data on carotid artery treatment was conducted in the five cases of neck tumor surgeries treated at Department of Surgical Oncology, the First Peoples Hospital of Lanzhou from March 2010 to May 2020. Surgical methods, including carotid artery resection and ligation, tumor-involved artery resection and vascular reconstruction, and tumor peeling and carotid rupture repairing were used, respectively. Results:Five cases were successfully operated on. One case of carotid artery ligation was followed by intermittent dizziness and decreased contra-lateral limb strength after the surgery. The remaining patients exhibited no neurological complications. A patient with cervical low-grade myofibroblastoma developed into lung metastases 8 months after the surgery. Another patient with cervical lymph node metastases in papillary thyroid cancer developed into lung metastases 24 months after the surgery. Conclusion:Currently, surgical methods for clinical treatment of diseased carotid arteries include carotid artery resection and ligation, simple tumor peeling, tumor invasion artery resection and vascular reconstruction, and interventional therapy. Each surgical method has its own advantages and disadvantages. Therefore, the choice of treatment depends on the patient's specific conditions, physician's clinical experience, and the equipment available.
Humans
;
Retrospective Studies
;
Carotid Arteries/pathology*
;
Head and Neck Neoplasms/pathology*
;
Thyroid Neoplasms/surgery*
;
Lung Neoplasms/pathology*
4.Meta-analysis of the clinical significance of thyroidectomy combined with central neck dissection in differentiated thyroid carcinoma at the first treatment.
Ronghao SUN ; Chao LI ; Jinchuan FAN ; Jifeng LIU ; Jianchao CHEN ; Bing ZHANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2014;49(2):157-163
OBJECTIVETo compare the differences in recurrence rates and surgical complications between thyroidectomy alone and thyroidectomy combined with central neck dissection as initial treatments to differentiated thyroid cancer and evaluate the clinic significance of central neck dissection for these patients.
METHODSThe literatures published in 1998-2013 were searched in Wanfang database, Chongqing VIP database, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Pubmed, Medline and Beijing Kangjian foreign medical journal full text service. According to the inclusion and deletion criteria, 30 articles were included. Of them 26 articles involved in complications, hypocalcemia and recurrent laryngeal nerve palsy as two major complications were involved in 26 articles and 24 articles respectively, and 26 articles involved in recurrence rate. RevMan5.0 software package was used to perform meta-analysis.
RESULTSTotal complication rate in experimental group (plus central neck dissection) was 13.08% higher than that in control group (thyroidectomy only), the odds ratio (OR) [95% confidence interval (95%CI)] was 2.32[2.02, 2.67], Z value was 11.80, P < 0.01. Hypocalcemia in the experimental group was 11.80% higher than that in control group, OR value [95%CI] was 2.58[2.21, 3.02], Z was 11.98, P < 0.01. The rates of recurrent laryngeal nerve paralysis were low in both experimental group (5.26%) and control group(3.95%), and OR value [95%CI] was 1.22 [0.94, 1.58], Z was 1.48, P = 0.14. Recurrence rate in experimental group was 2.23% lower than that in control group, OR value [95%CI] was 0.78 [0.63,0.97], Z was 2.35, P = 0.03.
CONCLUSIONCentral compartment dissection as initial treatment to differentiated thyroid cancer may reduce the risk of recurrence, but increases the incidence of total complications and hypocalcemia, and has no significant effect on the rate of the recurrent laryngeal nerve paralysis.
Humans ; Neck Dissection ; Neoplasm Recurrence, Local ; Thyroid Neoplasms ; pathology ; surgery
5.Bilateral thyroid carcinoma: a case report.
Chonghui WANG ; Rongrong WANG ; Cuihong DING
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(9):661-662
We describe a case of bilateral thyroid carcinoma in a 48-year-old woman. She was admitted to our hospital as a case of cervical nodular goiter. Multifocality of the thyroid nodules were evaluated by preoperative ultrasonography. The patient received bilateral thyroid lobe total resection and bilateral IV lymph node dissection. Medullary thyroid cancer was confirmed by intraoperative frozen pathology in the right lobe of thyroid gland and papillary thyroid microcarcinoma in the left lobe of thyroid gland. No tumor recurrence and metastasis were found after 3-months follow-up.
Female
;
Humans
;
Middle Aged
;
Thyroid Neoplasms
;
diagnosis
;
pathology
;
surgery
6.Isolated metastasis of the ascending ramus of the mandible of thyroid follicular carcinoma: a case report.
Siyao ZHANG ; Qingjia SUN ; Dongdong ZHU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2023;37(7):574-577
The mandibular metastatic spread of carcinoma from the thyroid gland is exceedingly rare. Follicular thyroid carcinoma is the second most common type of thyroid carcinoma,accounting for approximately 10% to 15% of all thyroid cancers. The prognosis of FTC is relatively satisfactory. Due to its rich blood transport, it is easy to metastasize hematological, with the main sites of metastasis are bone and lung. However,mandibular metastasis of thyroid follicular carcinoma is rare. We report a case of thyroid follicular carcinoma that metastasized to the ascending ramus of the mandible 21 years after surgery.The operation was successfully completed, and there was no recurrence during postoperative follow-up. Due to the absence of obvious clinical symptoms in the patient, the diagnosis and treatment were challenging. We have provided detailed radiographic and pathological images to facilitate understanding and discussion of the disease.
Humans
;
Adenocarcinoma, Follicular/pathology*
;
Thyroid Neoplasms/surgery*
;
Prognosis
;
Mandible
7.Value of reoperation after local resection of thyroid cancer.
Wei XU ; Pingzhang TANG ; Zhengjiang LI
Chinese Journal of Oncology 2002;24(2):185-187
OBJECTIVETo evaluate the rate of residual disease in the thyroid gland and rate of cervical lymph node metastasis after preliminary local resections in thyroid cancer.
METHODSFrom 1994 - 1999, 160 thyroid cancer patients who had previously been treated with nodulectomy or subtotal lobectomy in other hospitals were reoperated.
RESULTSThe rate of residual disease at the primary site was 42.5%. The lymph node metastatic rate at level VI was 28.1%. The rate of lymph node metastasis in those with enlarged lymph nodes in the ipsilateral internal jugular chain was 35.4%. The rate of laryngeal recurrent nerve injury was 12.5% at the first operation which is much higher than that of the second operation (1.9%).
CONCLUSIONBecause of the high rate of local residual disease, nodulectomy or subtotal lobectomy alone is not indicated for thyroid cancer. The exploration to level VI is needed for thyroid cancer. It is of utmost importance to be familiar with laryngeal recurrent nerve anatomy in thyroid surgery.
Adult ; Female ; Humans ; Male ; Neoplasm Recurrence, Local ; surgery ; Neoplasm, Residual ; surgery ; Thyroid Gland ; pathology ; surgery ; Thyroid Neoplasms ; surgery ; Thyroidectomy
8.Managing Thyroid Microcarcinomas.
Yonsei Medical Journal 2012;53(1):1-14
Papillary thyroid microcarcinomas (PTMCs) are the most common form of classic papillary thyroid carcinoma (PTC). PTMCs are typically discovered by fine-needle-aspiration biopsy (FNAB), usually with sensitive imaging studies, or are found during thyroid surgery in a patient without a previously known history of thyroid carcinoma. However, the definition of PTMC has not always been universally accepted, thus creating controversy concerning the diagnosis and treatment of PTMC. The aim of this review is to summarize the clinical features of PTMC and identify the widely differing opinions concerning the diagnosis and management of these small ubiquitous thyroid tumors.
Biopsy, Fine-Needle
;
Carcinoma, Papillary/mortality/*pathology/*surgery
;
Humans
;
*Neoplasm Staging
;
Thyroid Neoplasms/mortality/*pathology/*surgery
9.Papillary thyroid microcarcinoma.
Peng XIE ; Honfu DENG ; Tianzhi TAN
Journal of Biomedical Engineering 2009;26(5):1167-1170
The recent prevalence of ultrasonography (US) and US-guided fine needle aspiration biopsy (FNAB) can make us easily diagnose papillary carcinoma of 1.0 cm or less in maximal diameter, which is called papillary microcarcinoma. In the face of the fact that cervical lymph node metastasis and multicentricity are two prominent clinical characteristics of papillary thyroid microcarcinoma, the question How to treat papillary microcarcinoma has given rise to controversy. In this review, we discuss the clinical behavior, the appropriate therapeutic strategies, the factors affecting prognosis, and the methods for following up the patients with papillary thyroid microcarcinoma.
Biopsy, Fine-Needle
;
Carcinoma, Papillary
;
diagnosis
;
pathology
;
surgery
;
Humans
;
Prognosis
;
Thyroid Neoplasms
;
diagnosis
;
pathology
;
surgery