1.A Case of Carcinoma of the Thyroid and Cervical Esophagus Following Irradiation.
Jee Young LEE ; Hyun Jeung LIM ; Moo In PARK ; Seun Ja PARK ; Hee Kyung CHANG ; Kang Dae LEE
The Korean Journal of Gastroenterology 2005;46(2):129-132
It is well recognized that radiation can be carcinogenic for a wide variety of tumors, especially, in breast, thyroid, and bone marrow which appear to be radiosensitive. The criteria for establishing the dignosis of radiation- induced malignancy are the knowledge of prior irradiation and the appearance of a malignancy in the irradiated area. We report a case of carcinoma of the thyroid and esophagus following prior neck irradiation for thyroid mass.
Carcinoma, Squamous Cell/*etiology
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Esophageal Neoplasms/*etiology
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Female
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Humans
;
Middle Aged
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Neck/*radiation effects
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*Neoplasms, Radiation-Induced
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Thyroid Neoplasms/*etiology
2.Secondary Thyroid Papillary Carcinoma in Osteosarcoma Patients: Report of Two Cases.
Min Suk KIM ; Yoon Sang SIM ; Soo Yong LEE ; Dae Geun JEON
Journal of Korean Medical Science 2008;23(1):149-152
We report two cases of papillary thyroid carcinoma occurring after the successful treatment of osteosarcoma. One of the patients was administered with several alkylating agents and topoisomerase II inhibitor as part of the primary treatment of osteosarcoma. The onset of thyroid carcinoma occurred after 5 and 12 yr after cessation of the osteosarcoma therapy. All the patients involved in this study are alive and free of their malignancies. There have been eight case reports of these two malignancies occurring in the same patient. Thyroid carcinoma rarely occurs in patients with osteosarcoma; however, vigilant surveillance and long-term follow-up should be emphasized for all survivors.
Adolescent
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Bone Neoplasms/*therapy
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Carcinoma, Papillary/*etiology
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Female
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Humans
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Male
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Neoplasms, Second Primary/*etiology
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Osteosarcoma/*therapy
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Thyroid Neoplasms/*etiology
3.Anaplastic Thyroid Carcinoma Initially Presented with Abdominal Cutaneous Mass and Hyperthyroidism.
Kyu Hyoung LIM ; Keun Wook LEE ; Jee Hyun KIM ; So Yeon PARK ; Sung Hee CHOI ; Jong Seok LEE
The Korean Journal of Internal Medicine 2010;25(4):450-453
A 63-year-old female was admitted to our hospital with a tender abdominal wall mass about 15 cm in diameter, which she had for 1 month. About 1 week earlier, the patient had also perceived a mass in the neck area. Computed tomography revealed huge thyroid and periumbilical masses. The thyroid hormone levels were consistent with a hyperthyroid state. Pathological examination of the thyroid mass was compatible with anaplastic thyroid carcinoma (ATC) and the abdominal cutaneous mass was shown to be metastatic ATC. Despite palliative radiotherapy and chemotherapy, the patient died of respiratory failure on her 63rd day of hospitalization. This case demonstrates that abdominal cutaneous metastasis and hyperthyroidism can occur as initial manifestations of ATC. To our knowledge, this is the first reported case.
Abdomen
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Female
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Humans
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Hyperthyroidism/*etiology
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Middle Aged
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Skin Neoplasms/*secondary
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Thyroid Neoplasms/pathology
5.Metal stents in the treatment of neoplasm causing bronchial obstruction.
Guo-liang SHAO ; Chuan-ding YU ; Yu-tang CHEN ; Yan-ping YU ; Qi-rong XIA ; Wei-sheng LIAN
Chinese Journal of Oncology 2005;27(7):444-445
Aged
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Bronchoscopy
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Esophageal Neoplasms
;
complications
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Female
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Humans
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Male
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Middle Aged
;
Stents
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Thyroid Neoplasms
;
complications
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Tracheal Stenosis
;
etiology
;
therapy
6.Postoperative Complications of Thyroid Cancer in a Single Center Experience.
Yong Sang LEE ; Kee Hyun NAM ; Woong Youn CHUNG ; Hang Seok CHANG ; Cheong Soo PARK
Journal of Korean Medical Science 2010;25(4):541-545
The aim of this study was to investigate the complications following surgical treatment of thyroid cancer and the association between the extent of surgery and complication rates. A total of 2,636 patients who underwent surgery due to thyroid cancer were retrospectively reviewed to identify surgical complications. Complication rates were assessed according to the extent of surgery, which was classified as follows; less-than-total thyroidectomy with central compartment node dissection (CCND) (Group I, n=636), total thyroidectomy with CCND (Group II, n=1,390), total thyroidectomy plus ipsilateral neck dissection (Group III, n=513), and total thyroidectomy plus bilateral neck dissection (Group IV, n=97). The most common surgical complication was symptomatic hypoparathyroidism, of which 28.4% of cases were transient and 0.3% permanent. The other surgical complications included vocal cord palsy (0.7% transient, and 0.2% permanent), hematoma (0.5%), seroma (4.7%), chyle fistula (1.8%), and Horner's syndrome (0.2%). The complication rates increased significantly with increasing the extent of surgery from Group I to Group IV. The more extensive surgery makes more complications, such as hypoparathyroidism, seroma, and others.
Adult
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Female
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Humans
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Hypoparathyroidism/etiology
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Male
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Middle Aged
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Paralysis/etiology
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Parathyroid Glands/surgery
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*Postoperative Complications
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Retrospective Studies
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Seroma/etiology
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Thyroid Neoplasms/*complications/pathology/*surgery
7.Thyroid Cancer: We Need a Carcinogen-specific Genome Study.
Journal of Korean Medical Science 2015;30(12):1920-1921
8.Clinical manifestations and managements of post-neck dissection chylothorax.
Zhi-yu LI ; Wei TIAN ; Hong-ke CAI ; Ping WANG ; Yong-chuan DENG
Chinese Medical Journal 2013;126(13):2570-2572
Adult
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Aged
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Chylothorax
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etiology
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therapy
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Female
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Humans
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Middle Aged
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Neck Dissection
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adverse effects
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Retrospective Studies
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Thyroid Neoplasms
;
surgery
9.Influence of different thyroidectomy on perioperative blood calcium concentration.
Yi LAI ; Mengjia FEI ; Jiadong WANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(23):1873-1876
OBJECTIVE:
lo discuss the inmtluence of different thyroidectomy on perioperative blood calcium concentration.
METHOD:
Total number of patients was 240. These patients of thyroid tumors were recruited. Clinical and follow-up datum were retrospective analyzed.
RESULT:
Patients were divided into four groups by different operative methods. Group one was patients taken one-side thyroidectomy, group two taken one-side lymph node dissection plus, group three taken two-sides thyroidectomy,and group four taken one or two sides lymph node dissection plus. Group two was easier to become hypocalcemia and their calcium concentration decreased more remarkably, compared with group one. Patients taken two-sides thyroidectomy had the familiar outcome.
CONCLUSION
Patients taken lymph node dissection were easier to become hypocalcemia, compared with patients only taken thyroidectomy.
Calcium
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blood
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Humans
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Hypocalcemia
;
etiology
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Lymph Node Excision
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Neoplasm Recurrence, Local
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Retrospective Studies
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Thyroid Neoplasms
;
Thyroidectomy
;
adverse effects
10.Factors related to thyroid carcinoma in Zhejiang province: a matched case-control study.
F LU ; D N YING ; W W GONG ; W H ZHENG ; Q F HE ; L FANG ; J M ZHONG ; M YU
Chinese Journal of Epidemiology 2018;39(10):1387-1393
Objective: To explore the influencing factors related to thyroid carcinoma. Methods: Matched by sex, age and original residential areas, 659 pairs of cases and controls were recruited and studied. Methods including both single factor analysis and multivariate conditional logistic regression analysis were carried out to identify the influencing factors. Results: Multivariate conditional logistic regression analysis showed that higher education, being diabetic, alcohol intake, tea drinking, occupational physical activity and the frequency of eating fishes/eggs etc., were potentially protective to thyroid carcinoma. Depression, personal history of CT examination and less salt intake seemed to be risk factors on thyroid carcinoma. For males, factors as alcohol intake, tea drinking, occupational physical activity and frequent egg-eating appeared protective. For females, higher education, diabetes, tea drinking, occupational physical activity, frequent consumption of fishes/eggs, short duration of menstruation appeared as possibly protective. Conclusion: Higher education, diabetes, alcohol intake, tea drinking, occupational physical activity, frequent consumption of fishes/eggs, depression, personal history of CT examination and less salt intake served as potential influencing factors to thyroid carcinoma.
Alcohol Drinking
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Animals
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Case-Control Studies
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China/epidemiology*
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Feeding Behavior
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Female
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Male
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Risk Factors
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Tea
;
Thyroid Neoplasms/etiology*