OBJECTIVE: To determine the prevalence of thyroid incidentalomas detected by time-resolved magnetic resonance angiography (TRMRA) and to evaluate their clinical significance by using an ultrasonographic (US) and cytologic correlation. MATERIALS AND METHODS: We retrospectively reviewed 2010 consecutive TRMRA examinations performed at our institution between August 2006 and April 2010. The TRMRA findings of thyroid incidentalomas were analyzed according to location, size, as well as vascularity, and were correlated with the US findings and cytologic results. Each nodule was classified as suspiciously malignant, indeterminate or probably benign according to the US criteria recommended by the Korean Society of Thyroid Radiology. RESULTS: A total of 102 incidentalomas were detected in 90 of 2010 patients (5%). TRMRA showed homogenous hypervascularity in 48 (47%), inhomogeneous hypervascularity in 46 (45%), and hypovascularity in 8 (8%) thyroid nodules. At follow-up study, out of 26 patients with 30 incidentalomas on TRMRA, 27 nodules were identified on US. Of the 27 nodules, 24 (89%) nodule were classified as indeterminate, two (7%) as probably benign, and one (4%) as suspiciously malignant. Among the 16 nodules with available cytopathologic results, 14 (82%) were benign, one (6%) was indeterminate, and one (6%) was malignant. CONCLUSION: Thyroid incidentalomas are found in 5% of TRMRA examinations. Although their presence does not necessarily indicate malignancy, nonspecific findings of detected incidentalomas on TRMRA require further evaluation by US.
Adult ; Aged ; Aged, 80 and over ; Contrast Media/diagnostic use ; Female ; Humans ; Incidental Findings ; Magnetic Resonance Angiography/*methods ; Male ; Middle Aged ; Organometallic Compounds/diagnostic use ; Prevalence ; Retrospective Studies ; Thyroid Neoplasms/*diagnosis/epidemiology/ultrasonography ; Thyroid Nodule/*diagnosis/epidemiology/ultrasonography

INTRODUCTIONNodular goitres occur commonly in the population and this paper aims to determine the incidence of thyroid cancer found in these goitres.

MATERIALS AND METHODSThis is a retrospective, consecutive analysis of the histology of 268 nodular goitres that had been operated on, from 2002 to 2004, in a single tertiary hospital in Singapore.

RESULTSFifty-seven goitres (21.2%) with multiple nodules were found to contain a malignancy. Forty-four thyroid cancers (77%) were of the papillary type. The mean age of presentation for benign nodular goitres was 47.9 years. The mean age of presentation for malignant thyroid tumours was 49.25 years.

CONCLUSIONThe incidence of cancer is significant in nodular goitres and these malignant tumours are usually of the papillary type.

Biopsy, Fine-Needle ; Female ; Goiter, Nodular ; diagnostic imaging ; pathology ; surgery ; Humans ; Incidence ; Male ; Middle Aged ; Pathology, Clinical ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Singapore ; epidemiology ; Thyroid Neoplasms ; diagnosis ; epidemiology ; pathology ; Ultrasonography

No abstract available.
Bias (Epidemiology) ; Early Detection of Cancer/*statistics & numerical data ; Evidence-Based Medicine ; Humans ; Incidence ; Palpation/*statistics & numerical data ; Reproducibility of Results ; Republic of Korea/epidemiology ; Risk Factors ; Sensitivity and Specificity ; Survival Rate ; Thyroid Neoplasms/*diagnosis/*mortality/prevention & control ; Ultrasonography/*statistics & numerical data ; Unnecessary Procedures/*statistics & numerical data