No abstract available.
Thymus Hyperplasia*

No abstract available.
Thymus Hyperplasia*

Spontaneous pneumomediastinum in a term newborn without mechanical ventilation or underlying lung disease is rare. We present a case of a newborn baby who developed respiratory distress after birth and cystic pneumomediastinum which improved spontaneously with thymic hyperplasia as demonstrated on chest radiography, CT and MRI. The combination of cystic pneumomediastinum and thymic hyperplasia in a newborn has not been reported, thus far.
Humans ; Hyperplasia ; Infant, Newborn ; Lung Diseases ; Mediastinal Emphysema ; Parturition ; Respiration, Artificial ; Thorax ; Thymus Gland ; Thymus Hyperplasia

The thymus arises from the ventral wings of the third and fourth branchial pouches in the embryo. Subsequently, the thymus passes down to the mediastinum by the sixth week of gestation. Several unusual conditions such as remnants of the thymus and incomplete descent may occur along the path of descent. Therefore, thymic diseases such as thymoma, thymic hyperplasia, and thymic cyst can be found in the neck. Thymoma is the most common anterior mediastinal mass in adult. Rarely, it is presented as an anterior neck mass, commonly located in the anterolateral aspect of the neck or adjacent to the thyroid. Cervical thymic cyst is uncommon and usually occurs in the first and second decades. Cervical thymic cyst after the third decade is so rare that it is very difficult to diagnose preoperatively. We experienced two cases of cervical thymic neoplasm in the lower anterior neck in an adult. Here, we present the cases with a review of the related literatures.
Adult ; Embryonic Structures ; Humans ; Mediastinal Cyst ; Mediastinum ; Neck ; Pregnancy ; Thymoma ; Thymus Gland ; Thymus Hyperplasia ; Thymus Neoplasms* ; Thyroid Gland*

True thymic hyperplasia and ectopic thymus are very rare in children. In embryologic aspect, thymus is distributed around cervical area and ends up in mediastinum. This case is simultaneous thymic hyperplasia of neck and mediastinum. Ectopic thymus in the neck and thymic hyperplasia in the mediastinum in children were reported 2 and 7 cases respectively in Korea. In Clinical aspects, these thymic hyperplasia were presented by mass. So we should suspect these benign condition to avoid unnecessary operation or biopsy. We report a case of true thymic hyperplasia in the mediastinum with ectopic thymus in the neck in a 4-month-old male infant and review the relevant literature. We believe this is the first reported case in the world of true thymus hyperplasia in the mediastinum with cervical ectopic thymus in the neck.
Biopsy ; Child ; Humans ; Infant ; Korea ; Male ; Mediastinum* ; Neck* ; Thymus Gland* ; Thymus Hyperplasia*

Myasthenia gravis is a disorder characterized by fluctuating muscle weakness. This is frequently associated with thymoma or thymic hyperplasia, and thymectomy is an important step of treatment. We present one case of primary wquamous cell carcinoma of the thymus in myasthenia gravis. Review of literature indicate relative good prognosis.
Carcinoma, Squamous Cell* ; Muscle Weakness ; Myasthenia Gravis* ; Prognosis ; Thymectomy ; Thymoma ; Thymus Gland ; Thymus Hyperplasia

Possible association between systemic lupus erythematosus and disorders of thymus has been shown in several reposrts. But the association is clearly not common as judged by fewer than 20 case reports in the world literature. One case of systemic lupus erythematosus in a patient with thymic hyperplasia is described. The woman had been suffered from purpura, dry mouth and dry eyes and complained of chest discomfort. In this case, thymectomy did not modify the course of systemic oupus erythematosus. Systemic lupus erythematosus with thymic disorder is very rare so we report this case with a review of literatures.
Female ; Humans ; Lupus Erythematosus, Systemic* ; Mouth ; Purpura ; Thorax ; Thymectomy ; Thymus Gland ; Thymus Hyperplasia*

Giant thymic Hyperplasia is a rare lesion in children. We report a case of giant thymic hyperplasia in the right anterior mediastinum in a 2 year-old male patient. Presenting symptom was frequent cough and sputum, plain chest X-ray and computed tomography showed huge mass in the right anterior mediastinum. The tumor resection was done through a median sternotomy for the prevention of progression to atelectasis caused by mass effect and tissue diagnosis. An open biopsy specimen showed normal thymic architecture. The patient recovered without any problem and is doing well untill now. We report this rare case of giant thymic hyperplasia with review of the literature.
Biopsy ; Child* ; Child, Preschool ; Cough ; Diagnosis ; Humans ; Male ; Mediastinum ; Pulmonary Atelectasis ; Sputum ; Sternotomy ; Thorax ; Thymus Gland ; Thymus Hyperplasia*

We present herein an unusual case of multilocular thymic cyst, with prominent lymphoid follicular hyperplasia, in a 64-year-old man. It was incidentally founded as a mediastinal mass on chest radiography, during a routine health check-up. Computed tomography revealed a cystic lesion, which contains thick septa involving the thymus. The resected mass, 8x4 cm in diameter, involved the thymus and there is no adhesion or invasion into the adjacent tissue. The cut surface showed cystic spaces with thick white-tan firm wall, which cysts contained gelatinous material. Microscopically, the lesion was characterized by multiple cysts, lined by flattened cuboidal epithelium that was separated by thick walls, having a dense lymphoid tissue with lymphoid follicles. The patient was discharged without any complication and is well without evidence of recurrence for sixteen months.
Epithelium ; Gelatin ; Humans ; Hyperplasia ; Lymphoid Tissue ; Mediastinal Cyst ; Mediastinal Diseases ; Middle Aged ; Recurrence ; Thorax ; Thymus Gland

Thymic hyperplasia results from thymic regrowth after atrophy during a stressful period. Differentiation from recurrent or residual neoplasm may be an important consideration. Thymic hyperplasia is most problematic when it is observed in patients with malignant lymphoma. We report a case of thymic hyperplasia in which thymic enlargement is developed in a malignant lymphoma patient with high-dose chemotherapy and autologous peripheral blood stem cell transplantation and this condition is confirmed by the findings of serial chest computed tomography without chemotherpy.
Atrophy ; Drug Therapy* ; Humans ; Lymphoma* ; Neoplasm, Residual ; Peripheral Blood Stem Cell Transplantation ; Thorax ; Thymus Hyperplasia*