No abstract available.
Thymus Hyperplasia*

No abstract available.
Thymus Hyperplasia*

Spontaneous pneumomediastinum in a term newborn without mechanical ventilation or underlying lung disease is rare. We present a case of a newborn baby who developed respiratory distress after birth and cystic pneumomediastinum which improved spontaneously with thymic hyperplasia as demonstrated on chest radiography, CT and MRI. The combination of cystic pneumomediastinum and thymic hyperplasia in a newborn has not been reported, thus far.
Humans ; Hyperplasia ; Infant, Newborn ; Lung Diseases ; Mediastinal Emphysema ; Parturition ; Respiration, Artificial ; Thorax ; Thymus Gland ; Thymus Hyperplasia

The thymus arises from the ventral wings of the third and fourth branchial pouches in the embryo. Subsequently, the thymus passes down to the mediastinum by the sixth week of gestation. Several unusual conditions such as remnants of the thymus and incomplete descent may occur along the path of descent. Therefore, thymic diseases such as thymoma, thymic hyperplasia, and thymic cyst can be found in the neck. Thymoma is the most common anterior mediastinal mass in adult. Rarely, it is presented as an anterior neck mass, commonly located in the anterolateral aspect of the neck or adjacent to the thyroid. Cervical thymic cyst is uncommon and usually occurs in the first and second decades. Cervical thymic cyst after the third decade is so rare that it is very difficult to diagnose preoperatively. We experienced two cases of cervical thymic neoplasm in the lower anterior neck in an adult. Here, we present the cases with a review of the related literatures.
Adult ; Embryonic Structures ; Humans ; Mediastinal Cyst ; Mediastinum ; Neck ; Pregnancy ; Thymoma ; Thymus Gland ; Thymus Hyperplasia ; Thymus Neoplasms* ; Thyroid Gland*

True thymic hyperplasia and ectopic thymus are very rare in children. In embryologic aspect, thymus is distributed around cervical area and ends up in mediastinum. This case is simultaneous thymic hyperplasia of neck and mediastinum. Ectopic thymus in the neck and thymic hyperplasia in the mediastinum in children were reported 2 and 7 cases respectively in Korea. In Clinical aspects, these thymic hyperplasia were presented by mass. So we should suspect these benign condition to avoid unnecessary operation or biopsy. We report a case of true thymic hyperplasia in the mediastinum with ectopic thymus in the neck in a 4-month-old male infant and review the relevant literature. We believe this is the first reported case in the world of true thymus hyperplasia in the mediastinum with cervical ectopic thymus in the neck.
Biopsy ; Child ; Humans ; Infant ; Korea ; Male ; Mediastinum* ; Neck* ; Thymus Gland* ; Thymus Hyperplasia*

Myasthenia gravis is a disorder characterized by fluctuating muscle weakness. This is frequently associated with thymoma or thymic hyperplasia, and thymectomy is an important step of treatment. We present one case of primary wquamous cell carcinoma of the thymus in myasthenia gravis. Review of literature indicate relative good prognosis.
Carcinoma, Squamous Cell* ; Muscle Weakness ; Myasthenia Gravis* ; Prognosis ; Thymectomy ; Thymoma ; Thymus Gland ; Thymus Hyperplasia

Possible association between systemic lupus erythematosus and disorders of thymus has been shown in several reposrts. But the association is clearly not common as judged by fewer than 20 case reports in the world literature. One case of systemic lupus erythematosus in a patient with thymic hyperplasia is described. The woman had been suffered from purpura, dry mouth and dry eyes and complained of chest discomfort. In this case, thymectomy did not modify the course of systemic oupus erythematosus. Systemic lupus erythematosus with thymic disorder is very rare so we report this case with a review of literatures.
Female ; Humans ; Lupus Erythematosus, Systemic* ; Mouth ; Purpura ; Thorax ; Thymectomy ; Thymus Gland ; Thymus Hyperplasia*

Giant thymic Hyperplasia is a rare lesion in children. We report a case of giant thymic hyperplasia in the right anterior mediastinum in a 2 year-old male patient. Presenting symptom was frequent cough and sputum, plain chest X-ray and computed tomography showed huge mass in the right anterior mediastinum. The tumor resection was done through a median sternotomy for the prevention of progression to atelectasis caused by mass effect and tissue diagnosis. An open biopsy specimen showed normal thymic architecture. The patient recovered without any problem and is doing well untill now. We report this rare case of giant thymic hyperplasia with review of the literature.
Biopsy ; Child* ; Child, Preschool ; Cough ; Diagnosis ; Humans ; Male ; Mediastinum ; Pulmonary Atelectasis ; Sputum ; Sternotomy ; Thorax ; Thymus Gland ; Thymus Hyperplasia*

In the treatment of myasthenia gravis, thymectomy is generally accepted as the standard of therapy. For thymectomy, there have been various conventional open approaches including sternal splitting, but recently minimally invasive approaches have been increasingly applied. A 28-year-old man presenting with weakness of both hands and fatigability was diagnosed as having myasthenia gravis with thymic hyperplasia. He underwent a robot-assisted thymectomy with the 'da Vinci' surgical system. Through the right thoracic cavity, two thirds of the thymic gland was dissected, and the remainder was resected through the left; these procedures took, respectively, 1 hour and 30 minutes. The patient was discharged on the 8th postoperative day without complications. The minimally invasive approach with the 'da Vinci' surgical system is emerging as a popular choice and various advantages have been reported. Here we report the first successful case of robot-assisted thymectomy.
Adult ; Hand ; Humans ; Myasthenia Gravis ; Robotics ; Thoracic Cavity ; Thymectomy ; Thymus Hyperplasia

BACKGROUND: Thymectomy was known as an effective treatment modality of myasthenia gravis. In this paper, we analyzed the result of thymectomy and the factors affecting the postoperative symptom improvement. MATERIAL AND METHOD: We analyzed the medical records of 50 patients who received the thymectomy for myasthenia gravis from January 1997 to December 2001. RESULT: 39 patients showed symptom improvement. The effect ofthymectomy as a treatment is 78%. There was no statistically significant correlation between postoperative improvement and Sex, Age, the Weight of thymic tissue, preoperative symptom duration, and preoperative mestinon dosage. However, the thymic pathology and low grade preoperative symptoms were affecting the postoperative prognosis. CONCLUSION: Thymic hyperplasia showed good prognosis compared to thymoma. Low grade preoperative symptoms (Group I or IIA) also showed good prognosis. So, early thymectomy is recommendable for the good treatment results of myasthenia gravis.
Humans ; Medical Records ; Myasthenia Gravis ; Pathology ; Prognosis ; Pyridostigmine Bromide ; Thymectomy* ; Thymoma ; Thymus Hyperplasia