1.Endoscopic Evaluation of Biliary Strictures: Current and Emerging Techniques
Roy HUYNH ; Corinne OWERS ; Christopher PINTO ; Thuy-My NGUYEN ; Titus KWOK
Clinical Endoscopy 2021;54(6):825-832
The diagnosis of biliary strictures in clinical practice can be challenging. Discriminating between benign and malignant biliary strictures is important to prevent the morbidity and mortality associated with incorrect diagnoses. Missing a malignant biliary stricture may delay surgery, resulting in poor prognostic outcomes. Conversely, it has been demonstrated that approximately 20% of patients who undergo surgery for suspected biliary malignancies have a benign etiology on histopathology. Traditional tissue sampling using endoscopic retrograde cholangiography does not always produce a definitive diagnosis, with a considerable proportion of cases remaining as indeterminate biliary strictures. Recent advances in endoscopic techniques have the potential to improve the diagnostic and prognostic accuracy of biliary strictures.
2.Isolation and toxicity of Xanthomonas oryzae pv. oryzae in rice and a collection of phages against the pathogen
Ngoc Quynh Anh Pham ; Vo Thanh Phuc ; Pham Do Tra My ; Le Thi My Duyen ; To Hue Ngoc ; Nguyen Minh Thien ; Nguyen Hai Duong ; Le Thi Thuy Tien ; Le Phi Nga ; Hoang Anh Hoang
Malaysian Journal of Microbiology 2024;20(no.1):15-23
Aims:
The objective of the study was to isolate bacteriophages and conduct a comprehensive analysis of their potential against Xanthomonas oryzae pv. oryzae (Xoo) strains in the Mekong Delta, Vietnam.
Methodology and results:
Twelve Xoo strains were isolated from rice fields located in the Mekong Delta, Vietnam. Among these strains, three strains Xoo L019, L020 and L024, showed the highest disease index of bacterial blight. Four
phages specific to Xoo were isolated from soil, water and leaf samples, and their morphologies were determined. In a test against 12 Xoo strains, phage L541, MLA23 or W41 could infect 10 of the 12 Xoo strains, while phage LBH01 could infect 8 of the 12 Xoo strains. The stability of the phages to pH, organic solvents, UV-A and UV-B was also evaluated.
Conclusion, significance and impact of study
The initial characterization of the phages indicates their potential as biocontrol agents against bacterial blight in rice. The study is one of the very first studies about Xoo phages in rice in Vietnam.