1.Study on hepato-cellular protective action of Phyllanthus niruri L. in mice intoxicated by CCL4
Pharmaceutical Journal 1999;274(2):21-23
The hepatoprotective effects of extracts from Phyllanthus niruri obtained by different extraction procedures were evaluated using mice with acute hepatitis, included by CCL4. The effects of lowering the serum ALT and AST of these extracts were clearly demonstrated. It was founded that the hepatoprotective effect of extract produced a protective action better than a recovery one on. Activities of Extract 3 and ChophytolR were compared
Adenoma
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Hepatocytes
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Phyllanthus
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Carbon Tetrachloride
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Pharmaceutical Preparations
2.Prevalence of people with disabilities in Chi Linh
Thuy Thi Minh Nguyen ; Duy Sy Dang ; Huynh Van Hoang ; Quyen Ngoc Quach ; Michael Palmer
Journal of Medical Research 2008;58(5):99-105
Background: Surveys in disability are getting more and more attention from the Governments and contributes towards improve service provision for people with disabilities. Objective: To describe the prevalence of people with disabilities at The Chi Linh demographic and epidemiological surveillance system (CHILILAB), Hai Duong province in 2007. Subject and Method: The cross - cutting survey conducted in the CHILILAB which has a population of 65.438 people, the WHO questionnaire of disability screening was used. Result and conclusion: Disability prevalence in Chi Linh occurs in 28.2% of the population. It is noted that the disability prevalence increases significantly with age groups: 81.8% of those who are over 60, 58.2% those aged of 40 - 59 and only 8 - 9% of those aged under 40. In addition, the disability prevalence is higher in the rural areas, women, the poor and the illiterate. It is necessary to have more study on the prevalence of people with disabilities in wider ranges. \r\n', u'\r\n', u'\r\n', u'
Prevalence
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Disability prevalence
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Disability
3.Some characteristics of disabled people in Chi Linh district, Hai Duong province
Thuy Thi Minh Nguyen ; Quyen Ngoc Quach ; Huynh Van Hoang ; Duy Sy Dang ; Michael -- Palmer
Journal of Medical Research 2008;59(6):80-87
Background: People with disabilities have been coping with barriers that make it difficult for them to access public services. Many of them are poor, illiterate and out of work. Objective: To describe some characteristics of disabled people living in the communities of Chi Linh district, Hai Duong province. Subject and methods: Interview all of the 18.473 disabled people living in the seven communities of Chi Linh district, Hai Duong province. The contents of the interviews includes: economic-social information (income, education, job and martial status) and disability status (disability form and cause). Results: Nearly three fourths of disabled people are at the age of 45 and over. There are more women than men, with the male/female ratio at 1:1.8. Almost all of the disabled people are the Kinh in Chi Linh and 10.8% of them belong to the poor households. One in ten disabled people are illiterate and two thirds of disabled adolescents are at lower secondary school or lower. Difficulty in seeing is the most common among the kinds of disabilities, accounting for 81.9% of disabled people and about three fourths with one disability. Among the causes of disability, aging accounts for 71.5%, this is followed by illness. Conclusion: There is the need to reduce the rate of disability at the age of 45 and over, reducing the rate of sight related difficulties and increasing the accessibility of disabled people to educational services.
disability persons
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characteristics
4.Investigation of hemostatic disorders in patients with congenital heart diseases undergoing open heart surgery at Hue Central Hospital
Sang Si Dong ; Minh Ngoc Nguyen ; Hoa Thi Thuy Phan ; Thuan Thi Nguyen ; Dung Thi Tran ; Hanh Phuoc Huynh
Journal of Medical Research 2007;51(4):55-62
Background: Open heart surgery with cardiopulmonary bypass (CPB) causes haemostatic abnormalities which result in postoperative excessive bleeding. Objectives: To investigate haemostatic disorders before - after CPB and postoperative bleeding. Subjects and methods: Sixty congenital cardiac patients with and without cyanosis were recruited consecutively. Hematology and coagulation tests were done 1 day before operation, 15 minutes after protamine administration, 2 and 6 hours after the operation in the intensive care unit (lCU). Mediastinal chest tube drainage (MCTO) was measured for the first 6h in the ICU. Results: Significant differences between 2 groups could be found for red blood cells, hemoglobin, hematocrit, fibrinogen, D-dimer, fibrinogen degradation products (FOP), von Kaulla and platelet aggregation to epinephrine before operation (p < 0.05). There were not significant differences in platelets, PT, APTT, platelet aggregation to adenosine diphosphate (AOP) in the acyanotic and cyanotic patients (p > 0.05). Most hematology parameters were decreased significantly and hemostasis measurements were prolonged after operation in both groups (p < 0.05). There was also the significant difference in MCTO between 2 groups (p < 0.05). Conclusion: Coagulation, hemostasis and fibrinolysis disorders; thrombocytopenia and acquired transient platelet dysfunction may be responsible for bleeding complications after CBP \r\n', u'\r\n', u'
Heart Defects
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Congenital/ pathology
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epidemiology
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Hemostatic Disorders/ pathology
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diagnosis
5.Triterpenoids isolated from the aerial parts of Buxus latistyla Gagnep.
Quoc Hung VO ; Thuy Vi HUYNH ; Ngoc Minh Thao DOAN ; Thi Bich Nguyet HUYNH ; Thi Minh Hieu NGUYEN ; Thi Nhat Le DOAN
Hue Journal of Medicine and Pharmacy 2023;13(6):72-
Background: Buxus latistyla Gagnep. (Buxaceae) has been used as a remedy for treating malaria, haemoptysis, amoebic dysentery etc. However, its chemical constituents are still unknown. Thus, the aim of this study was to identify phytochemicals isolated from this plant. Materials and method: Aerial parts of B. latistyla were collected from Quang Tri province. Pure compounds were isolated using the combination of chromatographic methods. Structures of isolated compounds were identified by analyzing spectral data of nuclear magnetic resonance as well as by comparing with reported data. Results & Conclusion: Five triterpenes were isolated and identified including lupeol (1), lupenone (2), betulin (3), 20(29)-lupene-2α,3α-diol (4), 20(29)-lupene-2α,3α,28-triol (5). This is the first report about those phytochemicals of B. latistyla collected in Vietnam.