No abstract available.
Echocardiography ; Echocardiography, Three-Dimensional*

No abstract available.
Echocardiography, Three-Dimensional*

No abstract available.
Echocardiography, Three-Dimensional*

No abstract available.
Printing, Three-Dimensional*

No abstract available.
Printing, Three-Dimensional*

A Compton camera, which is based on the geometrical interpretation of Compton scattering, is a very promising gamma-ray imaging device considering its several advantages over the conventional gamma-ray imaging devices: high imaging sensitivity, 3-D imaging capability from a fixed position, multi-tracing functionality, and almost no limitation in photon energy. In the present study, a Monte Carlo-based, user-friendly Compton imaging simulator was developed in the form of a graphical user interface (GUI) based on Geant4 and MATLAB (TM). The simulator was tested against the experimental result of the double-scattering Compton camera, which is under development at Hanyang University in Korea. The imaging resolution of the simulated Compton image well agreed with that of the measured image. The imaging sensitivity of the measured data was 2~3 times higher than that of the simulated data, which is due to the fact that the measured data contains the random coincidence events. The performance of a stacking-structure type Compton camera was evaluated by using the simulator. The result shows that the Compton camera shows its highest performance when it uses 4 layers of scatterer detectors.
Imaging, Three-Dimensional ; Korea

Additive manufacturing (AM) is a collection of technologies based on the layer-by-layer manufacturing. Characterized by its direct manufacturing and rapidity, it has been regarded by the Economist Journal as one of the key techniques which will trigger the third industry reformation. The present article, beginning with a brief introduction of the history of AM and the process of its major technologies, focuses on the advantages and disadvantages and medical applications of the technique.
Medicine ; Printing, Three-Dimensional

Full arch models play an important role in clear aligner orthodontic therapy and the preparation of prosthodontic appliances. Three dimensional (3D) printed full arches are very popular with the benefit of easy production and good mechanical properties for fabricating clear aligner. However, the accuracy of 3D printed full arches after long storage have not been proved yet. The objective of this study was to estimate the long-term accuracy of 3D full arches produced by the four types of 3D printers (stereo-lithography apparatus (SLA), digital light projector (DLP), Polyjet™ (POL), and fused deposition modeling (FDM)) following an accelerated aging treatment. The highest accuracy was produced by POL (before treatment) and SLA (after treatment) group, respectively. Comparisons between absolute mean trueness for the 3D printed full arches before and after treatment indicated that the deviation of the trueness values of FDM group were significantly higher than those of other experimental groups (p<0.05). In addition, all trueness relative errors for FDM group were greater than 0.04 after treatment, which was high compared to those of other experimental groups. Therefore, the long-term storage of full arches fabricated by FDM type 3D printer is not recommended and the 3D printed full arches should be used immediately whenever possible.
Aging ; Printing, Three-Dimensional

Background: In this study, 3D printed floating tablet devices for Metronidazole (MTZ) were developed to prolong its exposure with Helicobacter pylori and eradicate it from causing peptic ulcer Objectives: To utilize Quality by Design (QbD) in the development of the tablet devices through Fused Deposition Modelling (FDM) 3D printing. This aimed to develop and construct optimized design dimensions of tablet devices subject for characterization. Methodology: Tablet designs were established using QbD, Design Failure Mode Effect and Analysis (DFMEA) and 2 factorial design. Four floating tablets devices were developed through FDM 3D printing using Polyvinyl alcohol (PVA) filament. Characterization tests determined their dimensions, density, floating mechanism, in vitro dissolution rate, drug release kinetics, surface morphology, infill and thermal characteristics. Significance of the QbD model was also assessed. Results: Density of all devices were less than 1.004 g/cm . The floating Lag time (FLT) showed instant floatation and Total Floating Time (TFT) lasted for an average of 1 hour. Drug release kinetics show Korsmeyer-Peppas kinetics. Thermal characteristics fall within o o 186.12 C-187.27 C. 3D CTX-ray results show accuracy of printing 3D renders. Tablet device 3 exhibited the best surface morphology, longest floating time and slowest drug release. Conclusion The study successfully developed 3D printed floating tablet devices for Metronidazole with sustained release mechanism. Thus, utilizing QbD in pre-formulation studies using novel technology is essential in optimizing drug dosage forms. Plots from Design Expert Software show the significant design models.
Printing, Three-Dimensional

Daikenchuto has been attracting nationwide attention in recent years, with its therapeutic efficacy on posto-perative complaints and complications. We treated three patients with acute abdomen using daikenchuto. They suffered from severe abdominal pains and abdominal radiographs showed small intestine gases. All three recovered from their pains or nausea after taking daikenchuto, and were discharged home without hospital admission. The use of daikenchuto against acute abdomen is recommended in emergency medicine.
Cases ; seconds ; Treated with ; Three ; Acute