The hydrogel burn wound dressing was prepared by gamma radiation cross-linking from aqueous solution mixture of polyvinyl alcohol, polyvinyl pyrrolidone, polyethylene oxide and met the requirements as bio-medical membranes. Chitosan into the hydrogel was degraded by gamma radiation and used as agents to increase antimicrobial activity and wound healing process. In this paper, the swelling characteristics of hydrogel dressing in water and plasma were investigated, the water loss of dressing was determined and the sterilization assurance level of products was appreciated obtaining international standard of ISO 9002 for medical products.
burns, Wounds and Injuries