In 8260 patients (61.1% female, 38.9% male) were detected HBV, HIV before operation or procedure in Vietnam Sweden hospital from 1999 to 2000. As a result, ratio of infectious HBV: 10.5%; HIV 1.2%; HBV-HIV: 2.8%. In surgeon group, ratio of infectious HBV: 11.1%; HIV: 2.0% it is higher than other groups.
HIV ; Surgery ; Hepatitis B virus

The survey of anemia among 201 pregnant women in community showed that: the anemia rate was 42.3%. Age group from 22-29 having highest anemia (59.1%). The anemia rate increased by number of pregnancies. The women in rural area had highest anemia rate than the women in other areas (65%).
Anemia ; Pregnant Women

Identified ratio of infectious HBV, HCV in 723 specimens of patient with HIV positive. As a result, ratio infectious HIV-HBV: 20,6%; HIV-HCV: 88.4% HIV-HBV-HCV: 19.1%. Ratio infectious HBV, HCV in male is higher than female. In 10 children age from new born to 18 months with HIV positive, 40% with HIV antigen P24 positive, 30% HCV positive.
HIV ; Hepatitis B virus ; Hepatitis C virus ; HIV Infections

Background: Nha Trang city located in central Viet Nam, has had dramatic economic development in recent years. The economic development has also leads to changes in the environment. Previous studies showed that cancers were closely related to environmental factors, but there was no study on this issue in Nha Trang city. Objectives: The study aimed to describe the cancer cases that were recorded in the cancer registration and the related environmental factors in Vinh Luong commune and the three neighborhood communes of Nha Trang city. Subjects and method: 192 patients who were diagnosed with cancer in the provincial general hospital and other hospitals from 1/1/2000 to 30/9/2006 and have resided in 4 above communes. Water samples collected from 14 water-wells from these communes were tested for chemical pollution and bacteria index. 20 sites in Van Dang village were tested for radioactive pollution levels. Results: Average crude morbidity of cancer per 100,000 inhabitants per year in Van Dang village and Vinh Luong commune and in the 4 communes as a whole, were 64.9, 51 and 53.3, respectively. The rates for male and female were 65.0 and 41.0, respectively. The most common cancers in women were cervical and breast cancers (11.8% and 9.2%, respectively). For men, leading cancers were liver cancer (31.9%) and lung cancer (14.7%). Almost all of the water samples did not meet the hygiene standard for nitrate (NO3) and coliform. Natural radioactive levels in these 4 communes were normal. Conclusion: Van Dang village had the highest cancer prevalence per 100,000 habitants compared to the other villages of Vinh Luong commune, but it was still lower than that of some other provinces. Most of the water samples collected from the water-wells did not met standard for nitrate levels and coliform.
Cancer ; environmental factor ; water pollution

Background: In Vietnam, Dengue Fever/Dengue Haemorrhagic Fever (DF/DHF) is one of ten contagious diseases causing epidemics with the highest prevalence.\r\n', u'Objectives: To describe some characteristics of DF/DHF epidemic in Khanhhoa province in 2005. \r\n', u'Subjects and methods: The descriptive study based on available data obtained from the surveillance reporting system.\r\n', u'Results: Total reported cases were: 5.365 (morbidity rate = 469.58 per 100.000) and 4 deaths (CFR = 0,074%).446 of 1.661 Mac Elisa tested cases were positives (positively = 26.9%). The positive cases in male were higher than that in female. Almost all of the positive cases were less than 15 years of age. Virus serotype D1 and D2 were isolated in the epidemic. 5 of 7 districts (except 2 mountainous districts) had outbreaks. The epidemic started in April and stopped in December. Ninhhoa district was the first location of the outbreak and Vanninh district was the last one. Geographical distribution of the epidemic was as follows: costal communes=54.6%, delta communes = 30.3%, urban communes =15.1%. The epidemic level was medium (>20% - <50% of communes having the epidemic). "Pilot intervention communes" had 4 times the higher risk of DF/DHF than "non pilot intervention communes". \r\n', u'Conclusions: IEC activities for preventing DF/DHF should be strengthened. For maintaining the low mosquito and breutau index, we need routine preventive actions. Authorities need to consider and to consolidate the activities of Pilot intervention communes. Coastal communes should be supplied with running water. \r\n', u'\r\n', u'
dengue fever/dengue haemorrhagic fever ; epidemic

Background: Plasma lipids are affected not only by dietary intake and life style but also by genetic factor. Objective: To discover the relationship between plasma lipids and the presence of LPL S447X and PAF-AH V279F in the bodies of rural Vietnamese population. Subject and Method: One hundred and ninety three subjects were randomly selected from rural areas in Ho Chi Minh city. The presence of LPL S447X and PAF-AHV279F polymorphism was determined using an Invader assay, and the plasma lipid levels were measured by an enzymatic method. A profile regarding the dietary intake was also made for each subject. Result and Conclusion: The frequency of LPL 447SX/XX (12.2%) polymorphism, PAF-AH Val279Phe mutation allele frequency (5.4%) in the Vietnamese was closely similar to that of other Asian populations. LPL447X polymorphism was found to be significantly associated with a higher HDL-C level in comparison to LPL 447S. LPL S447X affects plasma HDL-C and TG concentration in Vietnamese rural population.
Genetic factors ; plasma lipids ; rural area

The isolation of the MeOH extract from the flower bud of Magnolia biondii Pamp. using various column chromatographies and HPLC led to eleven neoglignan derivatives (1 - 11). Their structures were mainly determined by 1D and 2D NMR spectral data analysis and physiological methods. The isolated compounds (1 - 11) were tested for anti-allergic effects using IL-2 inhibitory assay in Jurkat T cells.
Chromatography ; Chromatography, High Pressure Liquid ; Flowers* ; Interleukin-2* ; Magnolia* ; Magnoliaceae ; Statistics as Topic ; T-Lymphocytes*

Objectives: Tuberculosis (TB) and drug-resistant TB (DR-TB) are national health burdens in Vietnam. In this study, we investigated the prevalence of rifampicin (RIF) and/or isoniazid (isonicotinic acid hydrazide, INH) resistance in patients with suspected TB, and applied appropriate techniques to help rapidly target DR-TB. Methods: In total, 1,547 clinical specimens were collected and cultured using the BACTEC MGIT system (Becton Dickinson and Co.). A resazurin microtiter assay (REMA) was used to determine the proportions of RIF and/or INH resistance. A real-time polymerase chain reaction panel with TaqMan probes was employed to identify the mutations of rpoB and katG associated with DR-TB in clinical isolates. Genotyping of the identified mutations was also performed. Results: A total of 468 Mycobacterium tuberculosis isolates were identified using the REMA. Of these isolates, 106 (22.6%) were found to be resistant to 1 or both antibiotics. Of the resistant isolates, 74 isolates (69.8%) were resistant to isoniazid (INH) only, while 1 isolate (0.94%) was resistant to RIF only. Notably, 31 isolates (29.24%) were resistant to both antibiotics. Of the 41 phenotypically INH-resistant isolates, 19 (46.3%) had the Ser315Thr mutation. There were 8 different rpoB mutations in 22 (68.8%) of the RIF-resistant isolates. The most frequently detected mutations were at codons 531 (37.5%), 526 (18.8%), and 516 (6.3%). Conclusion To help prevent new cases of DR-TB in Vietnam, it is crucial to gain a comprehensive understanding of the genotypic DR-TB isolates.

Backgroud: The aim of this study is to update on antibiotic resistance of common pathogenical bacteria isolated in Hue University of Medicine and Pharmacy Hospital (Hue UMP Hospital). Methodology: Use of the agar disk diffusion method to test the susceptibility to antimicrobial agents of 3709 bacterial strains from infected patients hospitalized in Hue UMP Hospital in 2020 - 2022. Results: Among 3709 strains of pathogenical bacteria isolated, S.aureus was found with the rate of 29.9%, followed by E. coli (24.5%), Pseudomonas aeruginasa (17.8%), Enterococcus spp. (11.8%), Klebsiella spp (9.7%) and Acinetobacter spp (4.1%). The proportion of bacterial isolates has changed, but Staphylococcus aureus is still highest rate. S.aureus is resistant to many antibiotics, but MRSA strains have decreased significantly, from 73.3% in 2020 to 62.5% in 2022. Pseudomonas aeruginosa was resistant to some of the group A recommended antibiotics such as ceftazidime, piperacillin-tazobactam with the rate of 56.6% and 48.7%. The percentage of E. coli with ESBL strains (+) was at 28.2% - 30.3%. Enterococus spp strains are still sensitive to vancomycin (83.1% - 91.9%). The rate of Klebsiella ESBL (+) is only 6.9% to 8.2%. The strains of Acinetobacter spp were highly resistant to Piperacillin (100%) and Ceftriaxone (96.5%) but they are still sensitive to imipenems 70 - 71%, highly sensitive to Doxycillin (95.2%) and Cefotaxime (88.4%). Conclusion: Many bacterial strains are resistant to many commonly antibiotics. Providing timely, regular, and effective management of antibiotic resistance patterns for common pathogenic bacteria in hospitals, will help reduce the risk of bacterial resistance.