Background: Subacute hematogenous osteomyelitis is a rare disease and difficult to diagnose. Hematogenous osteomyelitis is an infection caused by bacterial seeding from the blood. Acute hematogenous osteomyelitis is characterized by an acute infection of the bone caused by the seeding of the bacteria within the bone from a remote source.\r\n', u"Objectives: The study had two purposes: (1) Remark of Clinical and Xray syndrome of Subacute hematogenous osteomyelitis, and (2) Evaluation of the surgical results. Subjects and method:We operated on 42 patients with Subacute hematogenous osteomyelitis during 18 years period ( from 1984, October to 2005 December). Included 11 female, 31 male at the age from 4 to 12 years old. A rontgenographic classification was described by Gledhill & Roberts. The surgical debridement and irrigated with the antibiotic. Results: The patient's temperature is mildly elevated or normal, the pain isn't remarked. The WBC is normal. The cultures obtained by biopsy are positive in 8/42 patients. The lesions of type 1 in (88.1 % and type 2 in 11.9%. The follow - up: Good in 61.7%,Fair in 32.4%, Poor in 5.9%. Conclusions: The diagnosis and treatment are usually delayed, sometimes must be established by an open biopsy and cultures. Treatment with curettage of the lesion and administration irrigated with the solution antibiotics.\r\n", u'
Osteomyelitis/ pathology ; surgery

Background: Laparoscopic surgery is as very safe as traditional open surgery. A laparoscopic cholecystectomy is a surgical procedure during which the doctor removes your gallbladde. Objectives: This study was to assess the effect of local and intraperitoneal bupivacain infiltration on pain relief after laparoscopic cholecystectomy and the side effects of this technique. Subjects and method: In study group (n = 37), 25 mg bupivacain 0.25 % and 75 mg were infiltrated at Trocat incisions and at intraperitoneal surgery site, respectively. In placebo group (n = 44): no infiltration was used. VAS was measured controlling patient's pain during at rest, following inspiratory effort and movement; IV perfalgan requirement and the side effects of the technique were observed. Results: VAS at rest, following inspiratory effort and movement as well as perfalgan requirement during postoperative 6 hours were lower in study group (p < 0.05). \r\n", u'A significant decrease of heart rate after 10 - 30 minute of intraperitoneal infiltration of bupivacain was noted. Conclusions: Local and intraperitoneal bupivacain infiltrations had an effectiveness on pain relief during 6 hours after laparoscopic cholecystectomy. Moderate bradycardia was a main side effect of this technique. \r\n', u' \r\n', u'
Cholecystectomy/ methods ; Bupivacaine/ administration & ; dosage

Background: Acute gastroenterophathy usually caused by the Rota virus for children under 5 years old. Objectives: To present various types of data on epidemiology of ROTA virus diarrhea in Ho Chi Minh city from 12/2006-11/2007. Material and method: The data were collected from 500 stool specimens of diarrhea diagnosed chilren hosptalised at Thuy Dien Pediatric hospital 1, Ho Chi Minh city from December/2006 to November /2007. Results:There were 322 rotavirus-positive specimens, representing 64.4%. The proportions of monthly distribution of cases with diarrhea due to rotavirus were 90.1%, 54.39%, 85.37%, 74.51%, 72.92%, 41.67%, 26.67%, 58.33%, 79.31%, 52.63%, 69.05% and 57.78%, respectively. The numbers of rotavirus-positive cases in male and female were 216 (65.26%) and 106 (62.72%), respectively. The proportions of Rota virus positive children compared to total number of diarrheal cases with age 0-3, 3-6, 6-12, 12-24, 24-36 and over 36 months were 2.80%, 7.76%, 40.06%, 40.68%, 5.28% and 3.42%, respectively.\r\n', u'The results of typing identification indicated that the phenotypes of 98 among 100 specimens were identified (98%) in which there were sixty-one specimens of G1P8 (61%), one specimen of G2P8 (1%), fourteen specimens of G3P8 (14%), four of specimens of G4P8 (4%), eighteen specimens of GmixedP8 (18%). There were only two specimens of GnontypeableP8 (2%). Conclusion: Further studies should be carried out to clear this issue.\r\n', u'
Rotavirus ; gel type.

In this study, 23 oleanane-type triterpenoid saponins were isolated from a methanol extract of the roots of Pulsatilla koreana. The NF-kappaB inhibitory activity of the isolated compounds was measured in TNFalpha-treated HepG2 cells using a luciferase reporter system. Compounds 19-23 inhibited TNFalpha-stimulated NF-kappaB activation in a dose-dependent manner, with IC50 values ranging from 0.75-8.30 microM. Compounds 19 and 20 also inhibited the TNFalpha-induced expression of iNOS and ICAM-1 mRNA. Moreover, effect of the isolated compounds on PPARs transcriptional activity was assessed. Compounds 7-11 and 19-23 activated PPARs the transcriptional activity significantly in a dose-dependent manner, with EC50 values ranging from 0.9-10.8 microM. These results suggest the presence of potent anti-inflammatory components in P. koreana, and will facilitate the development of novel anti-inflammatory agents.
Anti-Inflammatory Agents ; Hep G2 Cells ; Inhibitory Concentration 50 ; Intercellular Adhesion Molecule-1 ; Luciferases ; Methanol ; NF-kappa B ; Peroxisome Proliferator-Activated Receptors* ; Pulsatilla* ; RNA, Messenger ; Saponins* ; Tumor Necrosis Factor-alpha

Purpose: Cranial magnetic resonance imaging (MRI) is recommended to identify intracranial lesions in girls with central precocious puberty (CPP). Yet, the use of routine MRI scans in girls with CPP is still debatable, as pathological findings in girls 6 years of age or older with CPP are limited. Therefore, we aimed to identify the prevalence of brain lessons in CPP patients stratified by age group (0–2, 2–6, and 6–8 years). Methods: This retrospective cross-sectional study recruited 257 girls diagnosed with CPP for 6 years (2010–2016). MRI was used to detect brain abnormalities. Levels of luteinizing hormone, follicle-stimulating hormone, and sex hormones in blood samples were measured. Results: Most girls had no brain lesions (82.9%, n=213), and of the minor proportion of girls with CPP that exhibited brain lesions (17.1%, n=44), 32 girls had organic CPP. Pathological findings were detected in 33.3% (2 of 6) of girls aged 0–2 years, 15.6% (5 of 32) of girls aged 2–6 years, and 3.6% (8 of 219) of girls aged 6–8 years. Hypothalamic hamartoma and tumors in the pituitary stalk were the most common pathological findings. The likelihood of brain lesions decreased with age. Girls with organic CPP were more likely to be younger (6.1±2.4 vs. 7.3±1.3 years, p<0.01) than girls with idiopathic CPP. Conclusion Older girls appeared to have a lower prevalence of organic CPP. Clinicians should cautiously use cranial MRI for girls aged 6–8 years with CPP.