1.Nerve function impairment in leprosy reaction
Journal of Medical Research 2008;55(3):73-77
Background: Nerve damage in leprosy reaction occurs very quickly, that can lead to paralysis for many peripheral nerves within 24 hours. Objective: To survey nerve function impairment in leprosy reactions. Subjects and method: 285 new leprosy patients treated from 1996 to 2000 at 22 districts in Ho Chi Minh city had leprosy reaction and estimated nerve functions. This was retrospective cross-section descriptive study. Results: This study included 70.2% men, age 15-45 years (71.9%) and most patients were manual laborers. There were 83.5% multibacillary (MB) and 16.5% paucibacillary (PB). 86.3% Reversal Reaction (RR), Erythemal Nodosum Leprosy (ENL) 13% and both 0.7%. 53% of leprosy reaction happened during Multi-Drug Treatment (MDT), at diagnosis 37.5%, before MDT 7.7% and after MDT 1.8%. Nerve function impairment was 38.2% in leprosy reaction; men had impaired nerve function 1.7 times higher than women (p<0.05). Nerve function impairment in RR and ENL as well as MB and PB were the same (p>0.05). MB (42%) has impaired nerve function higher than PB (26.1%) in RR (p<0.05, OR = 2.05). Conclusions: Leprosy reaction happened to men more frequent than women, essentially in MB and during MDT. One third of cases had nerve function impairment in leprosy reaction and also had a link between sex and nerve function impairment. MB was 2 times the impaired nerve function higher than PB in RR.
Nerve function impairment
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leprosy reaction
2.The situation of occupational accident in the construction facility cause and solution for prevention.
Journal of Practical Medicine 2002;435(11):44-46
The study on the document and field minutes and direct interview of workers, managers in the Ha noi General Construction company during 1991-1999 have shown that there were72 accidents with 104 persons with injuries in which 23 death, 53 moderate and severe injuries, 28 mild injuries, fall from high accounted for high rate (36,6%), the main cause (89%) of the accident that procedure and regulation of safe work were not obeyed properly.
Accidents, Occupational
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manpower
3.Dosage of celebroxib in drug products by method of capllary electrophoresis
Pharmaceutical Journal 2004;0(10):16-20
By the method of capillary electrophresis with MEKC technique on the preparation without processing of samples such as celebrex, zycel. The procedure of quantifisation of celebroxib was established. Statintrics results found that after 6 times of electrophresis the Corr Area ratio between celebroxib and our standards gave RSD ≤ 3% and t/t is ≤ 2%. Thus the procedure altained systematic compatibility for quantifying the preparation. The method had high sensitivity and selectivity. The results was precis and repeatable
Pharmaceutical Preparations/administration & dosage
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Methods
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Electrophoresis
4.Development situation of clinical study on traditional Chinese medicine for treating chronic renal failure
Journal of Practical Medicine 2005;510(4):42-44
Study on the trend of chronic renal failure treatment with traditional Chinese medicine in the recent years. Results: in clinical settings, serum urea and creatinine were decreased; renal blood supply was improved; metabolisms of serum lipid, phosphorus and calcium were improved; body immune was increased, and the quality of life was improved, thence the progression of disease was slowly. However, there were some problems with this treatment and it is needed further research.
Kidney Failure, Chronic
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Therapeutics
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Medicine, Chinese Traditional
5.Investigation of lactic acid bacteria’s abilities of transfering the anti-antibiotic gene by conjugation
Journal Ho Chi Minh Medical 2005;9(1):35-38
Isolate, purify, and identify bacteria from probiotic supplement. Results: 5 strains of lactic bacteria were determined, including: Steptococus feacalis; Streptococcus lactic; Bifidobacterium bifidum; Lactobaccillus acidophilus; Lactobacillus casei. Study the sensitivity of these bacteria with antibiotics, results showed that these bacteria were resistant to many antibiotics, especially oral antibiotics. Conjugative trial between Streptoccocus feacalis, Streptococus lactic, Bifidobacterium bifidum, lactobacillus acidophilus casei and E.coli K12, and conjugative trial of lactic bacteria together showed negative results. Therefore, probiotic product contained many lactic bacteria can be used concomitant with some oral antibiotics to prevent or treat digestive disorders
Anti-Bacterial Agents
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Bacteria
6.Remarks on surfactant therapy in premature infants with respiratory distress syndrome at intensive care unit of Children Hospital No 2 from January 2007 to July 2007
Le Thi Hanh Nguyen ; Thien Thanh Nguyen
Journal of Medical Research 2007;55(6):72-75
Background: Respiratory distress is one among the leading reasons cause mortality for infants especially for preterm babies or light weight babies. Surfactant therapy in premature infants can decrease mortality, duration of respiratory treatment, pulmonary air leaks and chronic lung disease. Objective: This study aims to assess the effect of surfactant therapy in premature infants with respiratory distress syndrome at Intensive Care Unit of Children Hospital N\xb0.2. Subjects and method:A cases study about premature infants less than 24 hours after birth with respiratory distress syndrome (RDS) admitted to intensive care unit and treated with surfactant from January 2007 to July 2007 at the Children Hospital No 2. There were 30 cases recruited. The data was collected and analyzed by EpiInfo software 2002.Results: Most of them improved in respiration status after using surfactant (96.7%); no case of air leak was seen; 3 bronchopulmonary dysplasia cases and 4 deaths due to nosocomial infection were seen. Conclusion: Surfactant therapy was effective in premature infants with RDS. In the case of having economic advantages, surfactant may be indicated for preventive treatment on the premature and light weigh infants without respiratory distress syndrome on clinical aspect.
Respiratory Distress Syndrome
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Newborn/ therapy
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Pulmonary Surfactant-Associated Proteins
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Infant
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Premature
7.Remarks on some clinical features and X-rays of 53 case of bronchogenic cyst
Dung Thi Kieu To ; Thanh Thi Vu ; Huy Le Pham
Journal of Surgery 2007;57(1):80-83
Background: Bronchogenic cyst is a disease caused by abnormal development of the bronchial tree during the fetal. Incidence of Bronchogenic cyst accounts for 6.5% of mediastinal tumor in children and 14.5% of mediastinal benign tumor. Objectives: To study clinical features, X-rays imaging of bronchogenic cyst and surgical indications in treatment. Subjects and method: A retrospective study was conducted on 53 patients with bronchogenic cyst (29 males, 24 females, aged between 18 and 69 years old), operated at Surgical department of Central Hospital of Tuberculosis and Lung from January, 2002 to December, 2005. Results:Clinical symptoms of bronchogenic cyst were nonspecific. However, some common symptoms were chest pain (64%), dry cough (51%) and hemoptysis (34%). The disease was common seen in bronchial parenchyma (98%), in right lung is 2 times higher than in left lung. Diameter of cyst was mainly from 5-10cm, round shape. The cyst edge is thin, clear and smooth. Treatment indication for bronchogenic cyst was surgery. Conclusion: When bronchogenic cyst was confirmed diagnosed, surgical indication was completely reasonable, it allowed eliminating complications of bronchogenic cyst.
Bronchogenic Cyst/diagnosis
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surgery
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X-Rays
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8.The prevalence of deltoid contracture in some areas of Viet Nam in 2006-2007
An Nhat Pham ; Vung Thi Vu ; Xuan Thi Thanh Le ; Tu Thanh Tran ; Vung Thi Vu ; Xuan Thi Thanh Le ; Tu Thanh Tran
Journal of Medical Research 2008;56(4):111-118
Background: Deltoid contracture can be a congenital or acquired condition. There were not any reports on deltoid contracture in English literature until 1960. In 2005 there were 170 children presented at the Viet Nam Pediatric Institute with deltoid contracture. These children came from different provinces, nationwide. The numbers of children who have this condition is increasing, but there were few studies on this problem in Viet Nam. Objectives: To identify the prevalence of deltoid contracture in Viet Nam in 2006-2007. Subjects and method: A cross-sectional study was done in 8 provinces representing for 3 geographic regions of Viet Nam., included Ha Noi, Ha Tay, Thanh Hoa and Lang son in Northern, Ha Tinh and Da Nang in Central and Tien Giang and Can Tho in the Southern region. 29,696 people aged from 1 to 60 years old at the baseline were involved in the study. The subjects were examined to identify the deltoid contracture based on defined criteria. Results: The prevalence of disease was 0.65% (0.83% in men and 0.51% in women). The rate was highest in the group of 6-10 years of age (1.81%). The prevalence was 0.82% in rural and 0.31% in urban area. Cases were found in all but 4 provinces (Da Nang, Tien Giang, Can Tho and Ha Noi) Conclusion: The prevalence of Deltoid contracture in Viet Nam was 0.65% in 2006-2007. It was more likely to occur in men than in women, in age group of 6 \u2013 10 than in other groups and in rural than in urban area.
Deltoid contracture
9.THE RISK FACTORS OF THE DELTOID CONTRACTURE OF LOCAL PEOPLE IN VIETNAM
An Nhat Pham ; Xuan Thi Thanh Le ; Vung Thi Vu ; Tu Thanh Tran
Journal of Medical Research 2008;58(5):87-93
Background: Deltoid contracture can be congenital or acquired. A cross-sectional study has been done in 8 provinces representing three regions in Vietnam. These are Ha Noi, HaTay, Thanh Hoa and Lang Son in the North, Ha Tinh and Da Nang provinces in the central, Tien Giang and Can Tho provinces in the South of Vietnam. Objective: To identify the risk factors of Deltoid contracture in Vietnam from 2006 - 2007. Subject and Method: 29696 people aged from 1 to 60 years old at the time of the survey were examined to diagnose the Deltoid contracture as well as being interviewed by structured questionnaire. Results: There was significant association between contracture of Deltoid muscle and some factors. These are antibiotics injection into the Delta muscle at 0 - 5 years old: OR = 2.93 (1.435,8); Antibiotics type (streptomycin) was injected at 0-5 years old: OR = 45.2 (13.1 - 167); having cicatrix: OR = 73.4 (46.1 - 116.9). There was no significant association between Deltoid fibrosis and vaccination (position and administration). Logistic regression was done to find that antibiotics injection into Delta muscle at 6 - 10 years old and antibiotics type (streptomycin) were significantly associated with Deltoid contracture. Conclusion: Risk factors of Deltoid contracture in this study were antibiotic injection at aged 0 - 5 years old, antibiotic type (Streptomycin) and having cicatrix. There was no significant association between Deltoid fibrosis and vaccination (position and administration).
Deltoid contracture
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Risk factors
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Vietnam
10.The sensitivity, specificity and diagnosed conformity of Rapid Diagnosis Test (Paracheck F test) compared with microscopic method for detecting Plasmodium falciparum
Tinh Thi Ta ; Hai Thanh Nguyen ; Ba Thanh Truong ; Thanh Kim Nguyen ; Thuan Khanh Le
Journal of Malaria and parasite diseases Control 2003;0(1):76-81
Background: Paracheck F.test is rapid diagnostic test that use to determine presence of histidine rich protein 2-HPR-2, a component of Plasmodium falciparum in total blood. Paracheck F.test producted by India\r\n', u'Objective: To study the sensitivity, specificity and diagnosed conformity of Rapid Diagnosis Test (Paracheck F test) compared with microscopic method for detecting P.falciparum \r\n', u'Subject and method: The study was conducted in 5 communes of Quang Tri province and 1 commune of Quang Binh province from September to November in 2006. A total of 470 blood samples were collected and examined with 2 methods for detecting P falciparum (Microscopy and Rapid Diagnosis Test- Paracheck). \r\n', u'Results:Among these blood samples, there were 438 samples having complete conformity in both two methods. 29 samples were negative with microscopy but positive with Paracheck. 3 samples were positive with Paracheck but negative with microscopy.\r\n', u'Conclusion: the sensitivity and specificity of Paracheck is 99% and 82%, respectively. Both microscopic and Paracheck methods have a high conformity in detecting P falciparum with the Kappa index of 0.84. \r\n', u'
Sensitivity
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specificity
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diagnosed conformity
;
Paracheck F test
;
microscopy