1.Isolation of Flavonoids from Excoecaria cochinchinensis Lour. var. cochinchinensis
Journal of Medicinal Materials - Hanoi 2003;8(4):103-107
The remedy Excoecaria cochinchinensis Lour. var. cochinchinensis (Euphorbiaceae) has been commonly used in folk medicine for the treatment of itches, furuncles, allergies. Previous reports have examined the chemical composition of the leaves, two compounds have been isolated and identified as gallic acid (FAD1) and ellagic acid (FAD 2). This study was carried out for the isolation and identification of the other chemical constituents. The leaves of E. cochinchinensis Lour. var. cochinchinensis were collected at Ha Noi city and Thai Binh province. The ethyl acetate extract of the leaves were successively chromatographed on silica gel G 60 and Sephadex LH-20 columns to afford two compounds named FAD 7 and FAD 8. The spectral analysis performed on EIMS, 1H-NMR and 13C-NMR has identified FAD7 as kaempferol 7-0-glycoside, and FAD 8 as kaempferol. These two flavonols were isolated from the leaves of the plant for the first time.
Plants
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Medicine, Traditional
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Biochemistry
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Flavonoids
2.Influence of the iodized salt program in community on the determination of thyroid gland function by using radioimmunoassay and immunometric assay
Journal of Preventive Medicine 2002;12(1):36-40
The study was conducted on 82 simple goiter patients and 91 Basedow patients after at least one year using iodized salt daily. The results showed that the uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and Basedow patients decreased after 2 and 24 hours taking an oral dose of radioactive iodine. Especially, the decrease was 40-50% in simple goiter patients. The concentration of T3, T4, TSH in the sera was as following: in the simple goiter patients, the concentrations of T3 and TSH were slightly decreased, and the T4 serum concentration was increased. However, all the values were still within the normal range of euthyroidism. In Basedow patients, the concentrations of T3, T4, and TSH have not changed.
Iodine
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Radioimmunoassay
;
Thyroid Gland
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Sodium Chloride, Dietary
3.Influence of use of iodine containing salt in the publicity on the thyroid function by some tests of nuclear medicine
Journal of Vietnamese Medicine 1998;6(2):1-5
The study was conducted in 82 simple goiter patients and 91 patients with Basedow’s disease after at least one year using iodized salt daily. The result showed:- The uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and patients with Basedow’s disease decreased after 2 and 24 hours taking an oral dose of radioactive iodine, specially in simple goiter patients decreased 40-50%. -The serum concentrations of T3, T4, TSH were following: in simple goiter patients, the serum concentrations of T3 and TSH were little decreased and the T4 serum concentration was increased. However, all the values were still in the normal range of euthyroidism. In patients with Basedow’s diseased the serum concentrations of T3,T4,TSH have not been changed
Nuclear Medicine
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Thyroid Function Tests
4.Effect of green bean (vigra radiata wilczek) on lipid peroxidation in vitro and in vivo
Ha Thi Nguyen ; Huyen Thi Thu Nguyen
Journal of Medical Research 2007;49(3):83-90
Background: Lipid peroxidation is considered that is one of the causes of pathological processes. Green bean is not only a food of high economic value but also a good medicine. Objective: To investigate the effects of green bean on (1) the lipid peroxidation in mitochondria of rat liver cell, (2) the index in blood of rabbits exposed to radiation: the activities of antioxidant enzymes (SOD, GPx), concentrations of MDA and TAS. Subjects and methods: In vitro experimental model was used to estimate the effects of green bean on lipid peroxidation in mitochondria of rat liver and in vivo experimental model was used to investigate the effects of green bean on the activities of free radicals in blood of rabbits exposed to radiation. Results and Conclusions: (1) Total green bean decreased the lipid peroxidation in mitochondria of rat liver cell without dependence onagents induced lipid peroxidation such as Fe3+.ADP/NADPH or Cumene hydroperoxid, (2) Green bean concurrently inhibited the decreased activities of SOD, GPx, TAS and the increased concentration of MDA in blood of rabbits radiated with 5 Gy dose. \r\n', u'\r\n', u'\r\n', u'
Antioxidants
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Lipid Peroxidation
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5.Chemical Composition and sedative effect of mimosa pudica
Journal of Medicinal Materials - Hanoi 2004;9(4):128-130
The extracts of the leaf of Mimosa pudica contain tannin, flavonoids, phytosterols, alcaloids and saponins. Aqueous and alcoholic extracts of the leaf exhibit sedative and hypnotic effects , but in alcoholic extract these effects were stronger
Medicine, Traditional
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chemistry
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Hypnotics and Sedatives
6.Preliminary results of the evaluation of respiratory function in asthmatic children
Journal of Medical and Pharmaceutical Information 2004;0(2):29-31
Studying 56 asthma patients, results showed that prevalence of asthma in stage 1 in 3-to-7-years old children was 42%. 12,5% of asthma children experienced chronic cough. 80.5% asthma children had medical history of allergy. House dust mite is a leading cause of asthma (51% patients had positive Prick test). In group 3-7 years old, 37.73% patients experienced obstructive syndrome, among them bronchial obstruction 3.5%, peripheral obstruction 28.79%, total obstruction 5.36%. 57.1% asthma children had improvement of pulmonary ventilation after using bronchodilators. 12.5% patients had increased resistance of airway that was found by breathing interruption method without cooperation of patients
Asthama
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child
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Respiratory Function Tests
7.Asian Fertility Expert Meeting (AFEM)
Journal of Medical and Pharmaceutical Information 2003;0(3):12-14
Asian Fertility Expert Meeting (AFEM) was taken place in Ho Chi Minh City from 20th to 23rd December, 2003. 11 reports were presented at the meeting. Out of them there were 2 reports of 2 Vietnamese lectures: Vuong Thi Ngoc Lan with report of experiences of using Orgalutran in Vietnam, and Ho Manh Tuong reported the development of first 12-25 months of age infants who were born by IVF/ICSI methods. The other reports and discussions focused on some topics: some forms of ovarian stimulation drugs in infertility treatment and in vivo fertilization (IVF)
Congresses as Topic
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Fertility
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Asian Continental Ancestry Group
8.HIV infection among surgical patients in Viet Duc hospital in the year 2003
Journal of Medical and Pharmaceutical Information 2003;0(3):22-24
25,873 patients, who came to VietDuc Hospital from Jan 1st 2003 to Dec 31st 2003, were performed HIV antibody tests. Result: among 25,297 samples are tested for HIV antibody, there were 292 cases HIV positive. The numbers of HIV infection among surgical patients in VietDuc Hospital increased day by day, accounted for 1.3% of patients underwent HIV antibody tests, especially the rate of HIV infection in young males (between 20 and 29 years old) was the highest. It is necessary to test HIV for pre-operative patients, special in high-risk people and to pay attention for health equipment, labour assurance for health care workers in hospital
HIV
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surgery
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hospitals
;
patients
9.To study the therapeutic effects of 'Sinh mach Bao nguyen" tea on low blood pressure
Journal of Medical and Pharmaceutical Information 2003;0(3):27-29
Clinical trial was carried out on 30 patients (28 females, 2 males at the age of 18 and 60 years old) with low blood pressure (systolic blood pressure <90mmHg and/or diastolic blood pressure <60mmHg) with other clinical symptoms such as headache, dizzy, fatigue, and insomnia were treated by 'Sinh mach Bao nguyen' tea- a herbal formula of traditional medicine. After 30 days of treatment, 93.33% of patients have higher blood pressure. Some clinical symptoms reduced significantly. There was no side-effect
Hypertension
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Blood Pressure
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Therapeutics
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Medicine, Traditional
;
Tea
10.Evaluation on chosen antibiotics in treatment for bacterial infection in Bach Mai Hospital
Pharmaceutical Journal 2005;0(5):28-31
138 cases with bacterial septicemia in Bach Mai Hospital were divided into two groups. The first group (n=51, 36.9%) was given single treatment (one antibiotic). The second group (n=87, 63.1%) was given combination treatment (two antibiotics). Due to the rate of cultured negative blood is high (about 70%), so the rate of initial treatment using antibiotic combination (63%) is higher than single antibiotic treatment (37%). Antibiotic groups used in combination treatment is aminosid antibiotics, in which amikacin is selected the most (27/37 cases, 72.9%). Third generation cephalosporin group makes the highest rate in single treatment (49%) as well as in combination treatment (58.7%). Quinolones, pefloxacin group used almost as initial method (single as well as in combination)
Anti-Bacterial Agents
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Therapeutics