1.Isolation of Flavonoids from Excoecaria cochinchinensis Lour. var. cochinchinensis
Journal of Medicinal Materials - Hanoi 2003;8(4):103-107
The remedy Excoecaria cochinchinensis Lour. var. cochinchinensis (Euphorbiaceae) has been commonly used in folk medicine for the treatment of itches, furuncles, allergies. Previous reports have examined the chemical composition of the leaves, two compounds have been isolated and identified as gallic acid (FAD1) and ellagic acid (FAD 2). This study was carried out for the isolation and identification of the other chemical constituents. The leaves of E. cochinchinensis Lour. var. cochinchinensis were collected at Ha Noi city and Thai Binh province. The ethyl acetate extract of the leaves were successively chromatographed on silica gel G 60 and Sephadex LH-20 columns to afford two compounds named FAD 7 and FAD 8. The spectral analysis performed on EIMS, 1H-NMR and 13C-NMR has identified FAD7 as kaempferol 7-0-glycoside, and FAD 8 as kaempferol. These two flavonols were isolated from the leaves of the plant for the first time.
Plants
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Medicine, Traditional
;
Biochemistry
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Flavonoids
2.Influence of the iodized salt program in community on the determination of thyroid gland function by using radioimmunoassay and immunometric assay
Journal of Preventive Medicine 2002;12(1):36-40
The study was conducted on 82 simple goiter patients and 91 Basedow patients after at least one year using iodized salt daily. The results showed that the uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and Basedow patients decreased after 2 and 24 hours taking an oral dose of radioactive iodine. Especially, the decrease was 40-50% in simple goiter patients. The concentration of T3, T4, TSH in the sera was as following: in the simple goiter patients, the concentrations of T3 and TSH were slightly decreased, and the T4 serum concentration was increased. However, all the values were still within the normal range of euthyroidism. In Basedow patients, the concentrations of T3, T4, and TSH have not changed.
Iodine
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Radioimmunoassay
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Thyroid Gland
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Sodium Chloride, Dietary
3.Influence of use of iodine containing salt in the publicity on the thyroid function by some tests of nuclear medicine
Journal of Vietnamese Medicine 1998;6(2):1-5
The study was conducted in 82 simple goiter patients and 91 patients with Basedow’s disease after at least one year using iodized salt daily. The result showed:- The uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and patients with Basedow’s disease decreased after 2 and 24 hours taking an oral dose of radioactive iodine, specially in simple goiter patients decreased 40-50%. -The serum concentrations of T3, T4, TSH were following: in simple goiter patients, the serum concentrations of T3 and TSH were little decreased and the T4 serum concentration was increased. However, all the values were still in the normal range of euthyroidism. In patients with Basedow’s diseased the serum concentrations of T3,T4,TSH have not been changed
Nuclear Medicine
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Thyroid Function Tests
4.Effect of green bean (vigra radiata wilczek) on lipid peroxidation in vitro and in vivo
Ha Thi Nguyen ; Huyen Thi Thu Nguyen
Journal of Medical Research 2007;49(3):83-90
Background: Lipid peroxidation is considered that is one of the causes of pathological processes. Green bean is not only a food of high economic value but also a good medicine. Objective: To investigate the effects of green bean on (1) the lipid peroxidation in mitochondria of rat liver cell, (2) the index in blood of rabbits exposed to radiation: the activities of antioxidant enzymes (SOD, GPx), concentrations of MDA and TAS. Subjects and methods: In vitro experimental model was used to estimate the effects of green bean on lipid peroxidation in mitochondria of rat liver and in vivo experimental model was used to investigate the effects of green bean on the activities of free radicals in blood of rabbits exposed to radiation. Results and Conclusions: (1) Total green bean decreased the lipid peroxidation in mitochondria of rat liver cell without dependence onagents induced lipid peroxidation such as Fe3+.ADP/NADPH or Cumene hydroperoxid, (2) Green bean concurrently inhibited the decreased activities of SOD, GPx, TAS and the increased concentration of MDA in blood of rabbits radiated with 5 Gy dose. \r\n', u'\r\n', u'\r\n', u'
Antioxidants
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Lipid Peroxidation
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5.The prevalence of pulmonary silicosis among underground coal-mine workers in Quang Ninh province
Journal of Practical Medicine 2002;435(11):22-25
The prevalence of pulmonary silicosis was investigated among 387 randomly selected underground coal-mine workers. Out of these, 37 cases diagnosed with pulmonary silicosis (9.6%). Diggers appeared to be at higher risk of developing silicosis than others, with prevalence rate ratio of 3.3 (95% CI, 1.38 - 7.92). There was a significant relationship between length of exposure and risk of pulmonary silicosis (Chi square for trend, p = 0.001). Underground coal-mine workers with more than years of exposure were found to have increased rates of silicosis than those with less than years (prevalence rate ratio = 4.0) (95% CI: 1.88-8.53). The rate of silicosis among smokers was significantly higher than among non-smokers, prevalence rate ratio = 7.9 (95% CI: 3.7 - 17). Free silica content in the coal dust was found to be high (range from 11.2 to 39.2%). This study has highlighted the problem that free silica does exist in the coalmines of ViÖt Nam and the workers, especially the diggers, are at risk of developing pulmonary silicosis. More comprehensive medical surveillance should be carried out in the future with the participation of the different ministries and coal corporations
Silicosis
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Prevalence
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Lung Diseases
6.Ovarian stimulation by FSH-HCG
Journal of Medical and Pharmaceutical Information 2002;10():35-36
The authors studied on 242 infertile cases due to an ovulation in 296 cycles of treatment by FSH-HCG from 1995 to 1997. The pregnancy rate is 28,51% of cases and 23,31% of cycles. The rate of spontaneous abortion plus embryos death in utero is high 52,7%. The rate of ovarian hyperstimulation is 8,45%. The monitoring of ovarian function by ultrasound and serum estradiol level is very important to prevent the risk of severe hyperstimulation. It is difficult to decrease the rate of abortion and embryo death in utero
Ovulation Induction
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Abortion, Spontaneous
8.Study on effect of Hegu laser He-Ne iradiation on some peripheral blood indexes
Journal of Medical Research 1998;7(3):31-36
20 healthy male students from 20-25 years of age were studied on the changes of peripheral blood indexes after the exact Hegu laser He-Ne irradiation with intensity 130 mW/cm2 for 2 minutes/point. 10 (changed most clearly) of 20 these students were irradiated laser outside the Hegu (1cm far from the Hegu) as the control group. Before irradiating, after laser 10, 30 minutes, vein blood was taken to investigate the following indexes: RBC, WBC, HGB, HCT, MCV, MCH, MCHC, PLT, NEUT/1, LYMPH/1, MDX/1, RDW-SD, MPV, P-LCR. The results showed that PLT, WBC, LYMPH/1 reduced markly after 10, 30 minutes (p<0.05); there were no differences of the other (RBC, HGB, HCT, MCV, MCH, MCHC, NEUT/1, RDW-SD, PDW, P-LCR) between before and after laser irradiation. There was no differences between before and after outside-Hegu laser He-Ne irradiation; the time when the peripheral blood indexes changed more clearly is at the 30th minute after irradiating.
Lasers
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Hematology
9.The mobility rehabilitation situation for cerebral palsy persons in Ha Tay provine
Journal of Practical Medicine 2004;471(1):23-25
The study was conducted on 238 cerabral palsy palsy patients aged 0-68 years in 19 commune of Ha Tay province. In 41,2% of patients mobility function rehabilited by common methods, among them, 82% by oriental traditional medicine, 13% by western medicine method and 5% by combined methods, 24% by special methods. Provincial hospital played a very modeste role in functional rehabilitation from cerebral palsy and in Hospital at district level, the role was nearly none.
Cerebral Palsy/rehabilitation
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Rehabilitation
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Epimiology
10.To finish the technique of identificating HLA in nasopharyngeal carcinoma patients
Journal of Practical Medicine 2004;471(1):25-26
By the technique of indirect immunofluoresceine using 18 diverse markers, in the hospital K- Ha Noi, study was performed to determine the capacity of foreign antigene expression of tumor cells in the cell surface making them identified by immunology system through HLA system on NPC < 75 years old age patients. This system played an essential role in the regulation and realization of immune response.
Carcinoma
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Nasopharyngeal Neoplasms
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Nasopharyngeal Diseases
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Diagnosis