1.Effect of green tea extract on lipid peroxydation and aortic atherosclerosis in cholesterol-fed rabbits
Journal of Vietnamese Medicine 2003;285(6):50-57
Green tea is one of the most widely consumed beverages in Vietnam. Polyphenol in green tea possess biological effects such as antitumoral, anticarciogenic, anti-inflammatory and reduce the risk of cardiovascular disease by increasing the plasma antioxidative capacity in human. Lipid peroxidation and oxidative modification of low-density lipoprotein have been implicated in human atherosclersis. Green tea extract with doses of 100 mg, 150 mg/kg body weight/day reduced levels of MDA plasma and injury of aortic atherosclerosis
Atherosclerosis
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Plant Extracts
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Tea
2.Preliminary study on the effectiveness of International Competitive Bids (ICB) for pharmaceuticals in Vietnam
Journal of Practical Medicine 2005;512(5):85-87
Study on 41 pharmaceutical companies in Hanoi city from March 1999 to February 2000. The results: there was an average of 46 pharmaceutical companies of sixteen countries bought the biding documents and about 43% of those companies submitted the bid documents. At each International Competitive Bids, the average of prices of pharmaceutical drugs were correlative with that announced by UNICEF, however, there was still a case of the mean prices of pharmaceutical drugs were higher than that announced by UNICEF. The prices of pharmaceutical drugs were considered lowest, lower than the average of prices of similar products, which were imported into the Vietnam market and announced by UNICEF
Pharmacy
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Pharmaceutical Preparations
3.Studying the changes of leukocyte, erythrocyte and bone-marrow of mice treated by gamma irradiation
Journal of Vietnamese Medicine 2005;0(2):22-25
Studying the effectiveness of irradiation on bone-marrow, the numbers of leukocyte, erythrocyte, hemoglobin of mice (25 normal mice and 35 mice treated by gamma irradiation with the dose of 600 rad/(100rad/day) (60 Co) showed that: Gamma irradiation reduced total of leucocytes, the number of different leucocytic (lymphocyte, granulocyte, mono and natural killer cells), the ratio of reticulocyte, number of mature erythrocyte and hemoglobin: Total of leucocytes (3,14 ± 1,58 in comparison with 13,45 ± 4,6); monocytes (0,05 ± 0,03 in comparison with 0,26 ± 0,13), lymphocytes (1,66 ± 0,36 in comparison with 6,34 ± 2,84). After gamma irradiation, the number of reticulocyte was 55%, mature erythrocyte was 73% and hemoglobin was 82%
Therapeutics
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Mice
4.Immunosuppressed model for experimental mice by cyclophosphamid
Journal of Vietnamese Medicine 2004;296(3):57-60
Study on white mices with age of 6-8 weeks, 18-20g body weight. They were divided into 3 groups: group 1 (control group): 30 mices; group 2: mices were immunesuppressed by 200mg cyclophosphamid per one kilogram of body weight, being checked after 5 days of injection; and 300mg cyclophosphamid per one kilogram (200mg on the first day and 100mg on the fifth day) and it was checked after 10 days of injection (group 3). The results: immunesuppressed model implemented by intraperitonial injection of 200mg per one kilogram of body weight checked after 5 days of injeciton. These parameters were used to assign the immune function
Immunosuppressive Agents
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Mice
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Animal Experimentation
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Cyclophosphamide
5.The effects of "DYI" on experimental Heterogenous skin graft and mixed lymphocytic culture of human
Journal of Vietnamese Medicine 2004;300(7):27-29
Heterogenous transplantation of skin was studied on two strains of mice BALB/C and Swiss.The subjects were divided into various groups :normal group, cyclophosphamid (CP) inhibited group, cyclosporin A (CPA) inhibited group, and the group processed with DY1. The onset of reject phenomenon of the graft and the completed reject of the graft in the groups of mice using CP, CPA and DY1 were more delayed in comparing with the controlled subjects. The cell numbers decreased and the percentage of transformed cells also decreased in all groups using CP, CPA and DY1
Skin Transplantation
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Mice
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Cells
6.Antibiotic resistance of Str.pneumoniae isolated in the recent years.
Journal of Preventive Medicine 2000;10(4):42-46
Outline on the antibiotic resistance of Streptococcus pneumoniae isolated during 1989-1995 in Viet Nam based on the data of antimicrobial susceptibility tests of NIHE and ASTS project. Comparing to the data from countries in South East Asis/India we found that: Str.pneumoniae is still susceptible to benzylpenicillin. B-lactams, macrolides, chloramphenicol. In many countries the reported incidence of drug-resistant Str.Pneumoniae has increased in the last year. The frequency and patterns of resistance vary in different geographic regions, countries and over different periods.
Drug Resistance
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Streptococcus pneumoniae
7.Extract and determination of polyphenols from Vietnamese green tea leaves
Journal of Medical Research 1998;7(3):35-39
Green tea infusion is one of the most popular drinks in many countries, especially in ASIA countries such as Japan, China and Vietnam. Green tea has been mounting regarding the anticancer, antiviral, antioxidant.
polyphenols
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green tea extract AR25
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Plants, Medicinal
8.Effect of green tea (Camellia sinensis) polyphenol on blood antioxydant status in rats with streptozocin-induced diabetes
Journal of Medical Research 2005;38(5):27-33
The diabetic patients are usually suffered from oxidation stress. Green tea is one of the good herbal medicines has been used for treatment of some diseases. Objectives: Evaluate change of antioxidant status in blood and effect of the green tea polyphenol on this change in the experimental diabetic rats. Methods: Using in vivo model to investigate some biological indicators in STZ - induced diabetic rats fed with high fat diet and to evaluate effect of the green tea polyphenol on the changes of these indicators. Results: Erythrocyte GPx activity and serum MDA concentration in STZ - induced diabetic rats was higher than that of normal and lipid metabolism disorder groups (p < 0.001) and effected of the green tea polyphenol. However, no change in erythrocyte SOD activity and plasma TAS level was observed. Conclusions: Green tea polyphenol improved blood antioxidant status in STZ - induced diabetic rats.
Diabetes Mellitus
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Tea
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Camellia sinensis
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Blood
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Oxidants
9.To finish the technique of identificating HLA in nasopharyngeal carcinoma patients
Journal of Practical Medicine 2004;471(1):25-26
By the technique of indirect immunofluoresceine using 18 diverse markers, in the hospital K- Ha Noi, study was performed to determine the capacity of foreign antigene expression of tumor cells in the cell surface making them identified by immunology system through HLA system on NPC < 75 years old age patients. This system played an essential role in the regulation and realization of immune response.
Carcinoma
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Nasopharyngeal Neoplasms
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Nasopharyngeal Diseases
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Diagnosis
10.Changes in erythrocyte, leucocyte and platelet in people having frequent contact with chemicals
Journal of Vietnamese Medicine 2004;295(2):23-26
In this study, 48 long-term exposed people with polychemicals (the male/female ratio is 1/3, the age from 23 to 44): such as organic and iso-organic acids: benzene, toluene and their coequals were investigated. 17 normal people not exposed with polychemicals as the control group. Results were shown following: quantity of erythrocyte was lower than control group but not significantly. Leucocytes especially neutrophils reduced significantly (p<0.001). 15/48 cases (30%) appereared lymphoblast. There is no difference in platelet between studied group and control group
Chemistry
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Diagnosis
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Erythrocytes
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Blood Platelets