1.Isolation of Flavonoids from Excoecaria cochinchinensis Lour. var. cochinchinensis
Journal of Medicinal Materials - Hanoi 2003;8(4):103-107
The remedy Excoecaria cochinchinensis Lour. var. cochinchinensis (Euphorbiaceae) has been commonly used in folk medicine for the treatment of itches, furuncles, allergies. Previous reports have examined the chemical composition of the leaves, two compounds have been isolated and identified as gallic acid (FAD1) and ellagic acid (FAD 2). This study was carried out for the isolation and identification of the other chemical constituents. The leaves of E. cochinchinensis Lour. var. cochinchinensis were collected at Ha Noi city and Thai Binh province. The ethyl acetate extract of the leaves were successively chromatographed on silica gel G 60 and Sephadex LH-20 columns to afford two compounds named FAD 7 and FAD 8. The spectral analysis performed on EIMS, 1H-NMR and 13C-NMR has identified FAD7 as kaempferol 7-0-glycoside, and FAD 8 as kaempferol. These two flavonols were isolated from the leaves of the plant for the first time.
Plants
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Medicine, Traditional
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Biochemistry
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Flavonoids
2.Influence of the iodized salt program in community on the determination of thyroid gland function by using radioimmunoassay and immunometric assay
Journal of Preventive Medicine 2002;12(1):36-40
The study was conducted on 82 simple goiter patients and 91 Basedow patients after at least one year using iodized salt daily. The results showed that the uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and Basedow patients decreased after 2 and 24 hours taking an oral dose of radioactive iodine. Especially, the decrease was 40-50% in simple goiter patients. The concentration of T3, T4, TSH in the sera was as following: in the simple goiter patients, the concentrations of T3 and TSH were slightly decreased, and the T4 serum concentration was increased. However, all the values were still within the normal range of euthyroidism. In Basedow patients, the concentrations of T3, T4, and TSH have not changed.
Iodine
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Radioimmunoassay
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Thyroid Gland
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Sodium Chloride, Dietary
3.Influence of use of iodine containing salt in the publicity on the thyroid function by some tests of nuclear medicine
Journal of Vietnamese Medicine 1998;6(2):1-5
The study was conducted in 82 simple goiter patients and 91 patients with Basedow’s disease after at least one year using iodized salt daily. The result showed:- The uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and patients with Basedow’s disease decreased after 2 and 24 hours taking an oral dose of radioactive iodine, specially in simple goiter patients decreased 40-50%. -The serum concentrations of T3, T4, TSH were following: in simple goiter patients, the serum concentrations of T3 and TSH were little decreased and the T4 serum concentration was increased. However, all the values were still in the normal range of euthyroidism. In patients with Basedow’s diseased the serum concentrations of T3,T4,TSH have not been changed
Nuclear Medicine
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Thyroid Function Tests
4.Effect of green bean (vigra radiata wilczek) on lipid peroxidation in vitro and in vivo
Ha Thi Nguyen ; Huyen Thi Thu Nguyen
Journal of Medical Research 2007;49(3):83-90
Background: Lipid peroxidation is considered that is one of the causes of pathological processes. Green bean is not only a food of high economic value but also a good medicine. Objective: To investigate the effects of green bean on (1) the lipid peroxidation in mitochondria of rat liver cell, (2) the index in blood of rabbits exposed to radiation: the activities of antioxidant enzymes (SOD, GPx), concentrations of MDA and TAS. Subjects and methods: In vitro experimental model was used to estimate the effects of green bean on lipid peroxidation in mitochondria of rat liver and in vivo experimental model was used to investigate the effects of green bean on the activities of free radicals in blood of rabbits exposed to radiation. Results and Conclusions: (1) Total green bean decreased the lipid peroxidation in mitochondria of rat liver cell without dependence onagents induced lipid peroxidation such as Fe3+.ADP/NADPH or Cumene hydroperoxid, (2) Green bean concurrently inhibited the decreased activities of SOD, GPx, TAS and the increased concentration of MDA in blood of rabbits radiated with 5 Gy dose. \r\n', u'\r\n', u'\r\n', u'
Antioxidants
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Lipid Peroxidation
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5.Changes in erythrocyte, leucocyte and platelet in people having frequent contact with chemicals
Journal of Vietnamese Medicine 2004;295(2):23-26
In this study, 48 long-term exposed people with polychemicals (the male/female ratio is 1/3, the age from 23 to 44): such as organic and iso-organic acids: benzene, toluene and their coequals were investigated. 17 normal people not exposed with polychemicals as the control group. Results were shown following: quantity of erythrocyte was lower than control group but not significantly. Leucocytes especially neutrophils reduced significantly (p<0.001). 15/48 cases (30%) appereared lymphoblast. There is no difference in platelet between studied group and control group
Chemistry
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Diagnosis
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Erythrocytes
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Blood Platelets
6.The tonic effects of "Thap Toan Dai Bo" pills on experimental rats
Journal of Practical Medicine 2004;484(8):6-8
The oral use of "Thap Toan Dai Bo" pills on experimental rats showed a tonic effect with a tonic coefficient of 1.9230.333. 80% of animals had had positive increase of weight. The dose of 0.1ml/10g and 0.2ml/10g, the effect of improving the memory was notified in the time of study. The staying time in light room T (second) and the rate of positive memory in the group of rat using "Thap Toan Dai Bo" was higher than control group with a statistical significant difference. The preparation has not poisonous, without side effect.
Medicine, Traditional
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Animal Experimentation
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Rats
7.Contribute to understand the effect of chemicals on immunological responding capacity of people having frequent and long contact
Journal of Vietnamese Medicine 2004;295(2):40-42
Study on 48 people, of whom 16 are male and 32 are female, from 23 to 44 years old. They were long exposed with poly-chemicals, such as organic and iso-organic acids: benzene, toluene and their coequals. The parameters have been used: phagocyte capablity and phagocyte index of neutrophils; E, rossett formed T cells. The results showed that: Phagocyte capability and phagocyte index of neutrophils decreased significantly comparing with control group (p<0.001)
Chemistry
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Allergy and Immunology
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Epidemiology
8.Circulating immune-complexes in acute leprosy, chronic hepatitis, pharynx cancer and acute myelogenous leukemia
Journal of Vietnamese Medicine 2004;295(2):49-52
20 patients with acute leprosy, 12 patients with chronic hepatitis, 34 patients with acute myelogenous leukemia, 48 patients with pharynx cancer. 31 normal healthy persons in the control group. Immune-complexes were fixed quantity by 2 methods: precipitating the immune-complexes with PEG having molecular weight 6.10¬3 and better method. Immune-complexes (+) were identified on acute leprosy, chronic hepatitis and acute diseases with the ratio of positive differences depending on disease, stage and the character of applying technique
Leprosy
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Hepatitis, Chronic
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Pharyngeal Neoplasms
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Leukemia, Myeloid, Acute
9.The real situation of health care for people at 3 extremly difficult commune of Ba Be district, Bac Kan province
Journal of Practical Medicine 2004;484(8):12-15
Assessment 3 communes of Khang Ninh, Thuong Giao and Cao Thuong, Ba Be district, Bac Can province showed that: the rate of poor households were very high, the pollution of the enviroment was very serious. On the health care: the medical stations at 3 communes were lack in number and insufficient quality. The medical index were very low:malnourished children at 3 communes were very high; remained malaria, the incidence of intestinal parasite in children were at high level; women who had gynecological examination was very low; the health care for mothers were very poor.
Delivery of Health Care
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Poverty
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Environment
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Child
10.Ratio of B virus infection in Muong minority pupils
Journal of Vietnamese Medicine 2004;295(2):53-55
115/400 Muong minority pupils of boarding school in Hoa Binh province, all studied subjects have 3 genarations of Muong minority (grandparents, parents and themshelves being Muong minority), from 15 to 19 years old. Using Sero check product of USA to examine the ratio of HBsAg. Results: 19.05% of the boys having HBsAg(+), 13.38% of the girls having HBsAg(+). So the ratio of HBsAg(+) in girls are lower than in boys but it is not significant. The ratio of HBsAg(+) at the age of 15 is 19.61%, the age of 16-17 is 14.74% and the age of 18-19 is 16.67%, there is not significant between groups
Hepatitis B virus
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Epidemiology
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Pupil