The remedy Excoecaria cochinchinensis Lour. var. cochinchinensis (Euphorbiaceae) has been commonly used in folk medicine for the treatment of itches, furuncles, allergies. Previous reports have examined the chemical composition of the leaves, two compounds have been isolated and identified as gallic acid (FAD1) and ellagic acid (FAD 2). This study was carried out for the isolation and identification of the other chemical constituents. The leaves of E. cochinchinensis Lour. var. cochinchinensis were collected at Ha Noi city and Thai Binh province. The ethyl acetate extract of the leaves were successively chromatographed on silica gel G 60 and Sephadex LH-20 columns to afford two compounds named FAD 7 and FAD 8. The spectral analysis performed on EIMS, 1H-NMR and 13C-NMR has identified FAD7 as kaempferol 7-0-glycoside, and FAD 8 as kaempferol. These two flavonols were isolated from the leaves of the plant for the first time.
Plants ; Medicine, Traditional ; Biochemistry ; Flavonoids

The study was conducted in 82 simple goiter patients and 91 patients with Basedow’s disease after at least one year using iodized salt daily. The result showed:- The uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and patients with Basedow’s disease decreased after 2 and 24 hours taking an oral dose of radioactive iodine, specially in simple goiter patients decreased 40-50%. -The serum concentrations of T3, T4, TSH were following: in simple goiter patients, the serum concentrations of T3 and TSH were little decreased and the T4 serum concentration was increased. However, all the values were still in the normal range of euthyroidism. In patients with Basedow’s diseased the serum concentrations of T3,T4,TSH have not been changed
Nuclear Medicine ; Thyroid Function Tests

The study was conducted on 82 simple goiter patients and 91 Basedow patients after at least one year using iodized salt daily. The results showed that the uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and Basedow patients decreased after 2 and 24 hours taking an oral dose of radioactive iodine. Especially, the decrease was 40-50% in simple goiter patients. The concentration of T3, T4, TSH in the sera was as following: in the simple goiter patients, the concentrations of T3 and TSH were slightly decreased, and the T4 serum concentration was increased. However, all the values were still within the normal range of euthyroidism. In Basedow patients, the concentrations of T3, T4, and TSH have not changed.
Iodine ; Radioimmunoassay ; Thyroid Gland ; Sodium Chloride, Dietary

Background: Lipid peroxidation is considered that is one of the causes of pathological processes. Green bean is not only a food of high economic value but also a good medicine. Objective: To investigate the effects of green bean on (1) the lipid peroxidation in mitochondria of rat liver cell, (2) the index in blood of rabbits exposed to radiation: the activities of antioxidant enzymes (SOD, GPx), concentrations of MDA and TAS. Subjects and methods: In vitro experimental model was used to estimate the effects of green bean on lipid peroxidation in mitochondria of rat liver and in vivo experimental model was used to investigate the effects of green bean on the activities of free radicals in blood of rabbits exposed to radiation. Results and Conclusions: (1) Total green bean decreased the lipid peroxidation in mitochondria of rat liver cell without dependence onagents induced lipid peroxidation such as Fe3+.ADP/NADPH or Cumene hydroperoxid, (2) Green bean concurrently inhibited the decreased activities of SOD, GPx, TAS and the increased concentration of MDA in blood of rabbits radiated with 5 Gy dose. \r\n', u'\r\n', u'\r\n', u'
Antioxidants ; Lipid Peroxidation ;

Effects of artesunate in the combination of other antimalarial drugs (primaquine, mefloquine or chloroquine) on activities of some murine plasma enzymes were studied: (1) The combination of artesunate with primaquine induced significantly plasma activities of GOT, GPT, LDH, - HBDH, CK and CK- MB in comparison with artesunate alone; (2) The combination of artesunate with mefloquine also induced significantly plasma activities of GOT, GPT, LDH, -HBDH, CK and CK- MB in comparison with artesunate alone; (3) The companation of artesunate with chloroquine reduced slightly plasma activities of GOT, GPT, LDH, -HBDH, CK and CK-MB. The results obtained in the study suggest that the combination of artesunate with primaquine or mefloquine on murine cellular damage is synergistic, while the combination of artesunate with chloroquine is probably antagonistic
Malaria ; artesunate ; drug therapy ; therapeutics ; Pharmaceutical Preparations

Acetonitril was used to extract ketoprofen from plasma. The revese phase HPLC was carried out with UV detector at 253nm column Nucleosil ODS 5m (4,6*250 mm); mobile phase: MeCN: AcOH: Triethylamin: H2O (50: 0.5: 0.3: 48.7 v/v); flow rate 0.85 ml/min. Experimental results proved that the method was stable, accurate and precise
Plasma ; Ketoprofen ; Chromatography, High Pressure Liquid

The rate of infertility in Vietnam is 13% of couples of reproductive age, in which the primary infertility is 1.5%; the secondary infertility with childless is 1.5% and with at least 1 living child is 2%. It means there are 5% of couples needing a treatment of infertility. The principal cause of infertility is the infections of genital tract leading to tubal occlusion in 40% of female infertility; the hydrotubation is done the proximal tubal occlusion. Surgery with coelioscopy is the most proper method for tubal occlusion; Pregnancy rate is 30% of the tubal occlusion cases. The rate of anovulation and dysovulation about 25%. The treatment of these cases is clomiphene citrate of HMG-HCG. The rate of hyperprolactinemia is 30% of amenorrheic women having galactorrhea or not. Bromocryptine pregnancy rate is more than 30%.
Infertility ; Sterilization, Tubal ; Disease Management

A study on 889 children ages of 6-15 in 8 schools in the urban of Hanoi and 367 childen ages of 6-15 of 2 schools in the suburb of Hanoi has shown that the rate of streptococcicosis A in the throat was 15.3%. There is no different of the rate of streptococcicosis. A between male and female and between pupils of primary school ages and pupils of secondary school. The children with upper respiratory tract infection were a higher risk of streptococcisis than others.
Streptococcus ; Population

The study involved 899 students from 8 schools in urban area and 367 students from 2 schools in 2 suburban districts of Ha Noi City. Ages of these children ranged from 6 to 15. Average value of ASLO antibody in children from Ha Noi urban and suburban areas is 92.5+/-81.7. Response of anti-streptolysin O antibody of Streptococci is nor different between male and female students neither between two age- groups.
Streptolysin O ; Antibody Formation ; Population

PDP has been verified to enforce the body’s immune system by improving both cellular immune and humour immune. Statistical analysis of blood cell quantity of rabbit before, during and after taking PDP showed that erythrocyte, leukocyte and platelet were proliferated significantly, especially leucocyte and platelet. G-globulin in the serum of white mouse tested by the dose of 5mg/10g and 10mg/10g of body weight has been found to increase significantly, the rate of albumin/globulin reduced. The same result also has been observed in the white sewer rat and rabbit. The effect of PDP on the grease was investigated on Tam hoang chicken. It was found that there was a reduction of the rate of the grease over body weight when the chicken was taken PDP. Electrocardiogram of rabbit serum, which was recorded at 2mV and 50cs/min proved that PDP did not cause any harmful effect on heart. Besides, no physical disease occurred on heart action
Pharmaceutical Preparations ; Animal Experimentation ; Animals ; drugs