1.Isolation of Flavonoids from Excoecaria cochinchinensis Lour. var. cochinchinensis
Journal of Medicinal Materials - Hanoi 2003;8(4):103-107
The remedy Excoecaria cochinchinensis Lour. var. cochinchinensis (Euphorbiaceae) has been commonly used in folk medicine for the treatment of itches, furuncles, allergies. Previous reports have examined the chemical composition of the leaves, two compounds have been isolated and identified as gallic acid (FAD1) and ellagic acid (FAD 2). This study was carried out for the isolation and identification of the other chemical constituents. The leaves of E. cochinchinensis Lour. var. cochinchinensis were collected at Ha Noi city and Thai Binh province. The ethyl acetate extract of the leaves were successively chromatographed on silica gel G 60 and Sephadex LH-20 columns to afford two compounds named FAD 7 and FAD 8. The spectral analysis performed on EIMS, 1H-NMR and 13C-NMR has identified FAD7 as kaempferol 7-0-glycoside, and FAD 8 as kaempferol. These two flavonols were isolated from the leaves of the plant for the first time.
Plants
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Medicine, Traditional
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Biochemistry
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Flavonoids
2.Influence of the iodized salt program in community on the determination of thyroid gland function by using radioimmunoassay and immunometric assay
Journal of Preventive Medicine 2002;12(1):36-40
The study was conducted on 82 simple goiter patients and 91 Basedow patients after at least one year using iodized salt daily. The results showed that the uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and Basedow patients decreased after 2 and 24 hours taking an oral dose of radioactive iodine. Especially, the decrease was 40-50% in simple goiter patients. The concentration of T3, T4, TSH in the sera was as following: in the simple goiter patients, the concentrations of T3 and TSH were slightly decreased, and the T4 serum concentration was increased. However, all the values were still within the normal range of euthyroidism. In Basedow patients, the concentrations of T3, T4, and TSH have not changed.
Iodine
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Radioimmunoassay
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Thyroid Gland
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Sodium Chloride, Dietary
3.Influence of use of iodine containing salt in the publicity on the thyroid function by some tests of nuclear medicine
Journal of Vietnamese Medicine 1998;6(2):1-5
The study was conducted in 82 simple goiter patients and 91 patients with Basedow’s disease after at least one year using iodized salt daily. The result showed:- The uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and patients with Basedow’s disease decreased after 2 and 24 hours taking an oral dose of radioactive iodine, specially in simple goiter patients decreased 40-50%. -The serum concentrations of T3, T4, TSH were following: in simple goiter patients, the serum concentrations of T3 and TSH were little decreased and the T4 serum concentration was increased. However, all the values were still in the normal range of euthyroidism. In patients with Basedow’s diseased the serum concentrations of T3,T4,TSH have not been changed
Nuclear Medicine
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Thyroid Function Tests
4.Effect of green bean (vigra radiata wilczek) on lipid peroxidation in vitro and in vivo
Ha Thi Nguyen ; Huyen Thi Thu Nguyen
Journal of Medical Research 2007;49(3):83-90
Background: Lipid peroxidation is considered that is one of the causes of pathological processes. Green bean is not only a food of high economic value but also a good medicine. Objective: To investigate the effects of green bean on (1) the lipid peroxidation in mitochondria of rat liver cell, (2) the index in blood of rabbits exposed to radiation: the activities of antioxidant enzymes (SOD, GPx), concentrations of MDA and TAS. Subjects and methods: In vitro experimental model was used to estimate the effects of green bean on lipid peroxidation in mitochondria of rat liver and in vivo experimental model was used to investigate the effects of green bean on the activities of free radicals in blood of rabbits exposed to radiation. Results and Conclusions: (1) Total green bean decreased the lipid peroxidation in mitochondria of rat liver cell without dependence onagents induced lipid peroxidation such as Fe3+.ADP/NADPH or Cumene hydroperoxid, (2) Green bean concurrently inhibited the decreased activities of SOD, GPx, TAS and the increased concentration of MDA in blood of rabbits radiated with 5 Gy dose. \r\n', u'\r\n', u'\r\n', u'
Antioxidants
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Lipid Peroxidation
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5.Some clinical and cytologic features of erythrocyte in peripheral blood and marrow of patients with myelodysplastic syndrome type persistent anemia
Journal of Vietnamese Medicine 2001;267(12):42-46
A total of 30 myelodysplastic syndromes (MDS) patients was analyzed to determine the clinical aspects and erythroid morphology in peripheral blood and bone marrow. The results are summarized as follows: 63.3% of patients was (50 years old. Male/Female ratio: 0.8. 46.7% were with lonely anemia and the rest were anemia combined with hemorrhages, infections, hepatosplenomegaly and lymphadenopathy. In peripheral blood: 63.4% of patients was with Hb<60g/l. 50% had normocrom - normocytic erythrocyte 96.7% of patients had dysmorphologic erythrocyte. In bone marrow: 46.6% were with hyperplasia of erythroid lineage, 33.6% were with hypoplasia of erythroid lineage, the rest (20%) were with normoplasia of erythroid lineage, 63.4% had dysmorphologic erythroblast, in which 36.7% was with ringed syderoblast
Myelodysplastic Syndromes
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blood
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diagnosis
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cytology
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Erythrocytes
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anemia
6.Study on Tobicom’s effect for 12th grade pupils myopia in high school Hanoi Amsterdam
Journal of Practical Medicine 2002;435(11):28-30
96 pupils (age: 17-18)with myopia(not congenital myopia) divided 2 groups. Group 1: 54 pupils: use of Tobicom: 2 tabs/day by oral within 3 months. Group 2: 42 pupils: use of Fish oils 6 tabs/day by oral within 3 months. The results: Group1 have good effect: improved the subjective symptoms and vision, especially slight myopia and newly suffered cases. The drug is well tolerated
Myopia
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Astigmatism
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pupil
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drug therapy
7.Primarily evaluation of values of tumor markers in the diagnosis of digestive and prostatic cancer
Journal of Practical Medicine 2002;435(11):22-24
Generality - Material - Method: The IMX PSA, CA 19-9, CEA are Microparticle Enzyme Immune Assay (MEIA) for the quantitative measurement of tumor marker in human serum. Results: number of health subjects 30 (20 men, 10 women), number of patients 56 (42 men, 14 women). The results of studies indicated that the PSA assay value is frequently elevated > 10ng/ml in the serum of subjects with prostatic cancer, the sensitivity 70.6%. CA 19-9 assay value is elevated > 37 U/ml in the serum of pancreatic cancer subjects, the sensitivity (83.4%). CEA assay value is elevated > 10 ng/ml in the serum of colorectal carcinoma, the sensitivity (54.5%).
Prostatic Neoplasms
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Tumor Markers, Biological
8.Ethmoidectomy via endoscopic technique
Journal Ho Chi Minh Medical 2003;7(3):171-175
With 4-7 cases of Rhinonasal polypsis in Eto-rhino-laryngologic center, from January 1998 to January 2001, in the age of 16-60 years. The ethmoidectomy via endoscopic technique and receive high efficacy result: 97% decrease nasal obstruction post op, 0% of orbital and intracranial complications, and specially 27% has appeared the minimal recurrent polyps on the anterior ethmoid which did not remove, just only use the steroid spray. Preparing the pre-op period with antibiotic, anti-inflammatory 93.7% and planned regularly patient's examination each month per year. Others factors such as asthma 13%, allergic zhinitis 24%, tobacco 15% were well studied to improve the result of the endoscopic ethmoidectomy and to limit the recurrent polyps
Endoscopy
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surgery
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therapeutics
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Ethmoid Bone
9.Isolation and identification of Asiaticoside from Centella asiatica (L.) urb
Journal of Medicinal Materials - Hanoi 2004;9(2):51-55
By column chromatograpy and thin layer chromatography, a purified substance named H3 was isolate from the dried powder of Rau Ma (leaf, stem and root of Centella asiatica). Basing on fusion point, IR spectrum, 1H-NMR, 13C-NMR, DEPT, HMQC, HMBC, COSY 90, the extracted substance was identified as C48H78O19
Triterpenes
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Centella
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isolation & purification
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Identification (Psychology)
10.Real situation of environment in farmers' houses, raising domestic cattle and poultries in On Luong - Phu Luong - Thai Nguyen province
Journal of Practical Medicine 2005;10():15-17
With the aim of investigation about the real situation of environment of farmers's houses in On Luong - Phu Luong - Thai Nguyen province, a cross-sectional and retrospective study was carried out. The results showed that: The environment in house and breeding facilities area is seriously contaminated by several factors such as human and animal waste, short distance from bleeding facilities to the house ect... The authors recommended that ; environment of farmers’ house, raising domestic cattle’s and poultries should be improved, primary health care should be applied more often for all farmers of this area.
Environment
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Cattle
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Poultry