1.Reproductive factors and risk of intermediate and high grade B-cell non-Hodgkin's lymphomas
Journal Ho Chi Minh Medical 2004;8(2):118-122
To interview 60 female patients with intermediate and high grade B-cell non-Hodgkin's lymphomas (NHL), each patient was paired with a control who is a neighbour on the age factor. Females who use oral contraceptive pills have a high risk in intermediate and high grade B-cell non-Hodgkin's lymphomas compared to controls. Among the mothers, those using anti-lactating drugs have a lower risk of NHL compared to controls. Menopausal patients have a higher NHL risk compared to women in the reproductive years, whereas menopausal women on hormone replacement therapy have a lower risk compared to controls
risk factors
;
Reproduction
;
Lymphoma, Non-Hodgkin
2.Sex chromosomal aneuploidy in spermatozoa of non-hodgkin lymphoma (NHL) patient before therapy
Journal Ho Chi Minh Medical 2004;8(3):176-178
Evaluation the ratio of sex chromosomal aneuploidy in NHL patient before therapy spermatozoa by FISH (Fluorescent Insitu Hybridization) technique. Comparison semen of four NHL patients before chemotherapy or irradiation with semen of four controls in the sperm bank. No statistically significant changes in semen in patient group compared to controls. The abnormal ratio with two somatic chromosome 8-8-X or 8-8-Y and diploidy X-Y-8-8 are higher than controls. The rate of aneuploidy in sex chromosome can increase if used in assisted fecundation
Lymphoma, Non-Hodgkin
;
Therapeutics
;
Spermatozoa
;
Aneuploidy
;
Sex
3.Epidemiological characteristics of HIV/AIDS in Nam Dinh province (1992- 2004)
Journal of Preventive Medicine 2005;15(5):101-106
Studies of HIV/AIDS in 1992-2004 show that HIV/AIDS endemic has been recorded since 1992. During 1999 - 2004, it has developed very fast. There were 1,618 accumulated HIV cases, 253 AIDS, and 186 deaths of AIDS. 100% of districts and towns with 81.3% of communes have people infected with HIV. The HIV cases in Nam Dinh town reached up to 59% of total number of the whole province. The HIV prevalence of the province is 81.6/ 100.000 people. Infection rate in Nam Dinh town is 409/100.000 people, 5.5 - 17 times higher than that in other districts. The trend of HIV infection rate among risk groups increased by 27,7% in drug abuser group and 5% in prostitute group. There is the need to inhance the prevention activities, media promotion, addressing social issues to curb the spread.
HIV/AIDS
;
Epidemiologic Studies
;
Epidemiology
4.The immunologic response of T-cell in large B-cell non Hodgkin lymphoma
Journal Ho Chi Minh Medical 2003;7(4):215-219
The authors conducted a retrospective study including 72 patients with non-Hodgkin lymphoma (NHL) with large B cell, to determine the percentage of CD3+, CD4+, CD8+, and natural killer cells by flow cytometry from the biopsy specimens before treatment, and compared these results to the patients’ outcomes. Results: the increased percentage of CD4 T cell in pretreated biopsy specimens correlated significantly to the patients’ outcomes. Patients with increased CD4+ had better 5-year survival than the others. Over 20% CD4+ cell infiltrated in the pretreated biopsy specimens were independent factors of non-recurrence. The increasing of active CD4+ in large B cell NHL offered a better prognosis, and was a background in immunologic therapy of B cell NHL
Lymphoma, Non-Hodgkin
;
Lymphoma, Lymphoblastic
;
immunology
5.Non-Hodgkin lymphomas recurrence in central nervous system
Journal Ho Chi Minh Medical 2005;9(1):38-43
A retrospective study was carried out on 32 patients with non Hodgkin lymphomas (NHL) in order to evaluate incidence rate, outcome and risk factors of central nervous system (CNS) recurrence. The results showed that: 1 patient had general manifestation and local CNS symptoms, 3 patients had CNS recurrence later on. The cumulative risk of CNS recurrence in 4 years was 19%. The CNS recurrence risk was 39% in high grade NHL, occurring usually in the first 14months, 22% in moderate grade NHL, occurring usually in the first 6 years and 7% in low grade NHL with higher degree of malignancy. In multi value analysis, NHL with high and moderate grades were independent risk factors for CNS recurrence. There are no clear evidences about role of CNS prophylaxis in patients with moderate and high grade of NHL. The survival time is 1-2 months
Lymphoma, Non-Hodgkin
;
Central Nervous System
;
Nervous System
6.Special histopathological features of the uncinate processes
Journal Ho Chi Minh Medical 2005;9(2):100-103
The study was carried out on 39 patients (18 male, 21 female, mean ages: 36.3 years old). Total of uncinate processes samples were 49. Of 39 patients, 29 patients were removed uncinate processes in one side and 10 patients were removed uncinate processes in two sides. The mean time of sinusitis was over 3 months in 32 cases (82%), 1 to 3 months in 3 cases (7.7%), and under 1 month in 4 cases (10.3%). 10 samples from uncinate processes in two side had the same histopathological lesions
Sinusitis
;
Diagnosis
7.The relationship of abnormal ultrasonographic findings and karyotype analysis in prenatal diagnosis
Journal Ho Chi Minh Medical 2005;9(4):205-209
Analyse the abnormal ultrasonographic findings of 112 pregnant women who were indicated for amniocentesis at Tu Du Obstetrics and Gynecology Hospital and Hung Vuong Hospital from February 2004 to September 2005. Abnormal ultrasonographic findings were divided into two groups: one group of major abnormalities that were significant relations to chromosomal abnormalities including atrio-ventricular channel and diaphragmatic hernia; the other group of minor abnormalities that were significant relations to chromosomal abnormalities and other small ultrasonographic abnormalities, major ultrasonographic abnormalities, biochemical analyses of maternal blood and age, etc. The results showed significant relations between the number and the categories of abnormal ultrasonographic findings and chromosomal abnormalities
Prenatal Diagnosis
;
Ultrasonography
8.The relationship between clinical types of sinusitis and microscopic lesion features of uncinate processes
Journal Ho Chi Minh Medical 2005;9(3):148-152
Study on 39 patients (18 males, 21 females, mean age: 36.3 years old) with chronic or recurrent anterior sinusitis, with or without nasal polyps, who were undergone naso-sinus endoscopies at Gia Dinh Hospital and HCMC University Medical Center from January to July 2004. Results: there was a change in microscopic imagines of uncinate processes like imagines of typical polyps although uncinate processes degeneration couldn’t be found. Polyps were common in chronic sinusitis, the rate of polyps increased along with the years of sinusitis
Sinusitis
;
Diagnosis
;
Endoscopy
9.Salpingostomy for ectopic pregnancy in National Hospital of Obstetrics and Gynecology
Thang Manh Nguyen ; Hang Thu Phan
Journal of Medical Research 2008;55(3):27-32
Background: Salpingostomy for ectopic pregnancy in patients who has aspirations to having a baby is a necessity. Objective: To discover the factors affecting the outcome of salpingostomy. Subjects and method: 400 patients with none or one baby treated by salpingectomy or salpingostomy for ectopic pregnancy in National Hospital of Obstetrics and Gynecology from July 2006 to June 2007 were studied. The data was analyzed with T test and logistic regression. Results: 92 of 400 patients (23%) were treated by salpingostomy. The risk of salpingectomy for patients with size of pregnancy mass >2 cm (measured by ultrasound) was 2.48 times higher than that of mass <=2 cm (95% CI: 1.50-4.12). All of cases with positive fetal heart beat were treated by salpingectomy. The danger of salpingectomy for patients with preoperative level of bhCG >3000 UI/L increased by 6.65 fold in comparison with that of bhCG <=3000 UI/L (95% CI: 2.99-15.27). The risk of salpingostomy for patients with the size of pregnancy mass >3 cm is 7.43 times as much as that of mass <=3 cm (95% CI: 3.89-14.39). Conclusion: The chance of salpingostomy for patients having the size of pregnancy mass <=3 cm and bhCG <=3000 UI/L was 24.1%.
Ectopic pregnancy
;
salpingostomy
10.Sleep Quality and Poor Sleep-related Factors Among Healthcare Workers During the COVID-19 Pandemic in Vietnam
Thang PHAN ; Ha Phan Ai NGUYEN ; Cao Khoa DANG ; Minh Tri PHAN ; Vu Thanh NGUYEN ; Van Tuan LE ; Binh Thang TRAN ; Chinh Van DANG ; Tinh Huu HO ; Minh Tu NGUYEN ; Thang Van DINH ; Van Trong PHAN ; Binh Thai DANG ; Huynh Ho Ngoc QUYNH ; Minh Tran LE ; Nhan Phuc Thanh NGUYEN
Journal of Preventive Medicine and Public Health 2023;56(4):319-326
Objectives:
The coronavirus disease 2019 (COVID-19) pandemic has increased the workload of healthcare workers (HCWs), impacting their health. This study aimed to assess sleep quality using the Pittsburgh Sleep Quality Index (PSQI) and identify factors associated with poor sleep among HCWs in Vietnam during the COVID-19 pandemic.
Methods:
In this cross-sectional study, 1000 frontline HCWs were recruited from various healthcare facilities in Vietnam between October 2021 and November 2021. Data were collected using a 3-part self-administered questionnaire, which covered demographics, sleep quality, and factors related to poor sleep. Poor sleep quality was defined as a total PSQI score of 5 or higher.
Results:
Participants’ mean age was 33.20±6.81 years (range, 20.0-61.0), and 63.0% were women. The median work experience was 8.54±6.30 years. Approximately 6.3% had chronic comorbidities, such as hypertension and diabetes mellitus. About 59.5% were directly responsible for patient care and treatment, while 7.1% worked in tracing and sampling. A total of 73.8% reported poor sleep quality. Multivariate logistic regression revealed significant associations between poor sleep quality and the presence of chronic comorbidities (odds ratio [OR], 2.34; 95% confidence interval [CI], 1.17 to 5.24), being a frontline HCW directly involved in patient care and treatment (OR, 1.59; 95% CI, 1.16 to 2.16), increased working hours (OR, 1.84; 95% CI,1.37 to 2.48), and a higher frequency of encountering critically ill and dying patients (OR, 1.42; 95% CI, 1.03 to 1.95).
Conclusions
The high prevalence of poor sleep among HCWs in Vietnam during the COVID-19 pandemic was similar to that in other countries. Working conditions should be adjusted to improve sleep quality among this population.