Prospective study on 107 bleeding peptic ulcer patients treated at Hospital No 103 from July 2001 to December 2002. Participants were divided into 2 groups. Group 1 received hemostatic therapy with polidocanol solution (PLS). Group 2 were treated by hypertonic saline-epinephrine (HSE) solution. Results: The general rate of successful hemostasis was 96.3%, in PLS group was 92.3% and in HSE group was 100%. There were not differences in the rates of initial hemostasis between 2 groups (p>0.05). Hemostatic effect was achieved after the first injection in 76.9% (40 patients) of PLS group and in 85.5% (47 patients) of HSE group. Some patients needed 2nd injections (PLS group: 15.4%, HSE group: 3.7%). Both solutions were effective in the treatment of bleeding peptic ulcer. HSE solution is safe, simple, low cost, and appropriate in Vietnam.
Peptic Ulcer ; Therapeutics ; Epinephrine ; Polyethylene Glycols

Remarks on the effectiveness of polidocanol solution in the treatment of peptic bleeding induced by duodenal ulcers in 52 patients (42 males, 10 females, between 17 and 86 years old) at the Military Hospital No.103 from February 2002 to November 2002. The results: polidocanol was tolerated well, nearly without allergy and toxicity. With a short of sub-elimination time, the drug was eliminated fast via stools and urine within 1.6 hours. Polidocanol solution was a very good hemostatic for peptic bleeding induced by duodenal ulcers. The successful rate was 92.3%, in which stable hemostatic condition after the first injection was observed in 76.9%; 12 patients needed the second injection (23.1%). There were 4 patients had to undergo surgery due to having crowed bleeding. There were no local or systemic events
Peptic Ulcer ; Endoscopy ; Therapeutics