Some sexual differentiation disorders are associated with gonadal neoplasia and increased incidence of testicular tumors has been discribed in the patients with, XY gonadal dysgenesis. The incidence of testicular tumors in infants and children are rare, representing only 1% of all pediatric solid tumors. In general, gonadal stromal tumors are one of the most characteristic endocrine tumors of the testis, endocrine activity occurs in at least 10-20%, among them Leydig cell tumors and Sertoli cell tumors are clinically important. Although the exact pathogenesis is unknown, endocrine activity due to estrogen secretion can be manifested clinically with gynecomastia or precocious puberty. We experienced and reported a child who visited for sexual precocity and had XY gonadal dysgenesis with Sertoli cell tumor.
Child ; Disorders of Sex Development ; Estrogens ; Gonadal Dysgenesis ; Gonads ; Gynecomastia ; Humans ; Incidence ; Infant ; Leydig Cell Tumor ; Male ; Puberty, Precocious ; Sertoli Cell Tumor* ; Testicular Neoplasms ; Testis

No abstract available.
Sertoli-Leydig Cell Tumor*

No abstract available.
Sertoli-Leydig Cell Tumor*

No abstract available.
Sertoli-Leydig Cell Tumor*

No abstract available.
Sertoli-Leydig Cell Tumor*

A Sertoli-Leydig cell tumor (SLCT) is an extremely rare type of sex cord stromal tumor of the ovary, which mainly secretes testosterone, thus manifestations of hyperandrogenism commonly appear. This paper shall discuss a case of a postmenopausal woman who presented with pelvic organ prolapse, large left ovarian cyst and mild signs of hyperandrogenism. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, which on microscopic examination of the specimens, revealed a Mature cystic teratoma on the left ovary and an incidental finding of a well-differentiated SLCT, on the grossly normal-looking ovary. This histopathologic diagnosis of SLCT explained the patient’s hyperandrogenic characteristics. Authors likewise discussed the proper management of SLCT, including immunostaining and need for adjuvant chemotherapy.
Sertoli-Leydig Cell Tumor

No abstract available.
Testicular Neoplasms*

Leydig cell tumors are the most common non-germ cell tumors of the testis, and they account for 1-3% of all testicular tumors. They most commonly present as a testicular mass and/or with endocrine symptoms. This tumor is characterized by its endocrine manifestations, which are due to the tumor's capacity to secrete hormones. We report here on one case of a patient with Leydig cell tumor; the patient was without symptoms and the tumor was not detected on the physical examination.
Humans ; Leydig Cell Tumor* ; Physical Examination ; Testicular Neoplasms ; Testis

Leydig cell tumors are rare, constituting only 1-3% of all testicular tumors; but they are still the focus of interest due to the difficulties in determining their exact nature and subsequent type of treatment. Generally, there appears to be no association with cryptorchidism, but there have been reports of Leydig cell tumors in cryptorchid testes. Herein, a case of a Leydig cell tumor in cryptorchidism is reported.
Cryptorchidism ; Leydig Cell Tumor* ; Male ; Testicular Neoplasms ; Testis*

No abstract available.
Puberty, Precocious* ; Sertoli-Leydig Cell Tumor*