1.Granulosa Cell Tumor of Scrotal Tunics: A Case Report.
Korean Journal of Radiology 2001;2(2):117-120
We report a case of adult granulosa cell tumor arising in the scrotal tunics. The patient was a 34-year-old man who presented with right scrotal swelling, first noticed four months previously. Under the initial clinical impression of epididymo-orchitis, antibiotic treatment was instituted but there was no response. The paratesticular nodules revealed by ultrasound and magnetic resonance imaging mimicked intratesticular lesion, and radical orchiectomy was performed. Although several cases of adult testicular granulosa cell tumor, have been reported, the occurrence of this entity in the paratesticular area has not, as far as we are aware, been previously described.
Adult
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Case Report
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Granulosa Cell Tumor/*diagnosis/surgery
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Human
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Magnetic Resonance Imaging
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Male
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Scrotum/*pathology/*ultrasonography
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Testicular Neoplasms/*diagnosis/surgery
2.Diagnosis and treatment of yolk sac tumor of the testis with hydrocele in children: report of 7 cases.
Sheng-Song HUANG ; Deng-Long WU ; Ya-Ping GUI ; Xin ZHAO ; Hua XIE
National Journal of Andrology 2013;19(11):1007-1010
OBJECTIVETo study the clinical characteristics of yolk sac tumor of the testis with concomitant testicular hydrocele in children and the association between the two conditions in order to improve the diagnosis and treatment of the disease.
METHODSWe retrospectively analyzed the clinical data of 7 cases of stage-I yolk sac tumor of the testis with concomitant testicular hydrocele. The patients ranged in age from 6 to 14 (mean 11) months. As treatment, we performed radical high spermatic cord orchiectomy after diagnosis established on intraoperative frozen sections, and conducted follow-up visits by medical examination, serum alpha-fetoprotein (AFP) detection, chest X-ray, ultrasonography and CT for 3-41 (mean 17) months, every month in the first year, every 3 months in the second year and every 6 months in the third year after surgery.
RESULTSPostoperative pathology confirmed yolk sac tumor in all the cases, with negative incisal margin. The level of serum AFP were decreased to normal in 6 cases within 1 month after surgery, all diagnosed as at stage I, and cured without chemotherapy. The other 1 case, with the serum AFP level of 116 microg/L at 1 month after operation, was diagnosed as at stage II and received PVC chemotherapy, but lost to follow-up at 3 months post-operatively.
CONCLUSIONYolk sac tumor of the testis with concomitant testicular hydrocele is easily misdiagnosed in children. Ultrasonography is necessitated as routine examination in its diagnosis. Radical high spermatic cord orchiectomy can be performed for patients in stage I, and chemotherapy should follow for those in stage II. Its prognosis is similar to that of other yolk sac tumors. Hitherto, there has been no evidence for a definitive correlation between yolk sac tumor of the testis and hydrocele in children.
Endodermal Sinus Tumor ; diagnosis ; diagnostic imaging ; surgery ; Humans ; Infant ; Male ; Orchiectomy ; Retrospective Studies ; Spermatic Cord ; surgery ; Testicular Hydrocele ; diagnosis ; diagnostic imaging ; surgery ; Testicular Neoplasms ; diagnosis ; diagnostic imaging ; surgery ; Testis ; pathology ; Ultrasonography ; alpha-Fetoproteins ; metabolism
3.Desmoplastic small round-cell tumor of the paratesticular region: a case report and review of the literature.
Jian-Jun SHA ; Jian-Wei LU ; Jian-Shan ZHU ; Xu-Yuan HUANG ; Yi-Xin WANG
National Journal of Andrology 2007;13(10):918-920
OBJECTIVETo investigate the clinical and pathological features of paratesticular desmoplastic small round cell tumor (DSRCT), and to improve the diagnosis and treatment of the disease.
METHODSOne case of paratesticular DSRCT was studied retrospectively and a considerable amount of related literature from Medline and Chinese journals reviewed. The patient was a 27-year-old man presenting with a painless testicular mass in the left hemiscrotum. On physical examination, a cystic mass was palpable while the testis was not in the left hemiscrotum.
RESULTSDuring the operation the paratesticular area was found full of multiple nodular tumor masses of various sizes ranging from 0.5 cm to 1.5 cm in diameter. Pathological examination showed the characteristic histological pattern of nests of small undifferentiated cells embedded in a dense fibrous stroma. The tumor presented an immunohistochemical feature of epithelial, mesenchymal as well as neural multidirectional differentiation. Following testicular tumor orchiectomy, chemotherapy was performed with DDP, VP16, ifosfamide and EPI. Three years follow-up found no tumor recurrence.
CONCLUSIONDesmoplastic small round cell tumor has a specific clinicopathologic stigmata, usually occurring in young males, for which surgical resection with chemotherapy is the treatment of choice. DSRCT located in the paratesticular region may have a better prognosis than its more frequently abdominal counterpart.
Adult ; Carcinoma, Small Cell ; diagnosis ; drug therapy ; surgery ; Combined Modality Therapy ; Fibroma, Desmoplastic ; diagnosis ; drug therapy ; surgery ; Humans ; Male ; Testicular Neoplasms ; diagnosis ; drug therapy ; surgery ; Treatment Outcome
4.A rare case of intratesticular leiomyoma.
Zhan Peng YONG ; Zhen Bang LIU ; Cora CHAU ; Kian Tai CHONG
Singapore medical journal 2015;56(9):e145-6
A 47-year-old man presented with a scrotal swelling. Ultrasonography of the testes showed that it was an extratesticular swelling. However, the swelling was intraoperatively found to be intratesticular. Histology showed an intratesticular leiomyoma, which is extremely rare.
Diagnosis, Differential
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Humans
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Leiomyoma
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diagnosis
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diagnostic imaging
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surgery
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Male
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Middle Aged
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Scrotum
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pathology
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Testicular Neoplasms
;
diagnosis
;
diagnostic imaging
;
surgery
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Treatment Outcome
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Ultrasonography
6.Inguinal recurrence of malignant mesothelioma of the tunica vaginalis: one case report with delayed recurrence and review of the literature.
Giovanni LIGUORI ; Giulio GARAFFA ; Carlo TROMBETTA ; Rossana BUSSANI ; Stefano BUCCI ; Emanuele BELGRANO
Asian Journal of Andrology 2007;9(6):859-860
Aged
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Epididymis
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pathology
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surgery
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Humans
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Inguinal Canal
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Male
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Mesothelioma
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diagnosis
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pathology
;
surgery
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Neoplasm Recurrence, Local
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diagnosis
;
pathology
;
surgery
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Orchiectomy
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Testicular Neoplasms
;
diagnosis
;
pathology
;
surgery
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Testis
;
pathology
;
surgery
;
Time Factors
7.Value of ultrasonography in the diagnosis and differential diagnosis of testicular tumor.
Wei WANG ; Zhen-hua GONG ; Yu-tian DAI
National Journal of Andrology 2007;13(5):424-427
OBJECTIVETo evaluate ultrasonography in the diagnosis and differential diagnosis of testicular tumor.
METHODSUltrasound findings and post-operation pathological results were retrospectively studied in 172 men with testicular mass 1998 to 2005.
RESULTSOf the total number, 50 cases were testicular hematoma, 13 testicular cyst, 26 testicular inflammatory node, 25 testicular tuberculosis and 58 testicular tumor. Among 59 testicular tumor cases, 50 were germ cell tumor (including 41 cases of seminoma and 9 cases of nonseminoma germ cell tumor), 6 were non-germ cell tumor and 3 were secondary tumor. The sonographic features of typical seminoma, teratomas, epidemic cyst, interstitial cell tumor and malignant lymphoma were obvious.
CONCLUSIONUltrasonography, contributive to the preliminary diagnosis and differential diagnosis of testicular tumor and capable of evidence for further treatment, can be the first choice in medical imaging for the diagnosis of testicular tumors.
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Diagnosis, Differential ; Endodermal Sinus Tumor ; diagnostic imaging ; Hematoma ; diagnostic imaging ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Seminoma ; diagnostic imaging ; Teratoma ; diagnostic imaging ; Testicular Diseases ; surgery ; Testicular Neoplasms ; diagnostic imaging ; Ultrasonography
8.Combined modality therapy for primary choriocarcinoma in the pineal region: report of two cases.
Xi-An ZHANG ; Song-Tao QI ; Lu-Xiong FANG ; Yu-Ping PENG ; Jia-Lin ZHANG ; Bing-Hui QIU ; Chun XIA
Journal of Southern Medical University 2007;27(8):1193-1195
We report two rare cases of primary choriocarcinoma in the pineal region verified histologically. In both cases, the pre-operative serum level of human chorionic gonadotropin (HCG) was significantly elevated to 128-/+935.7 and 9 -/+088.9 mIU/ml, respectively, and serum alpha-fetoprotein (AFP) was negative. The tumors were microsurgically removed, and postoperative hydrocephalus were treated by endoscopic third ventriculostomy. Both patients underwent chemotherapy and radiotherapy. After adjunctive treatment, the serum HCG decreased within normal range. During the two-year-long follow-up, no radiological (MRI) evidence was found to suggest recurrence in MR imaging, and the serum HCG was normal in one patient, but mildly elevated in the other. HCG measurement can be crucial to the diagnosis and post-treatment monitoring of choriocarcinoma, and radical surgical tumor removal and combined modality therapy including chemotherapy and radiotherapy may ensure good results.
Adolescent
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Child
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Choriocarcinoma
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blood
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diagnosis
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surgery
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therapy
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Combined Modality Therapy
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Follow-Up Studies
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Humans
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Magnetic Resonance Imaging
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Male
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Pinealoma
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blood
;
diagnosis
;
surgery
;
therapy
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Recurrence
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Testicular Neoplasms
;
blood
;
diagnosis
;
surgery
;
therapy
;
Treatment Outcome
9.Diffuse embryoma of the testis: report of a case.
Yang-li ZHU ; You-ping YANG ; Jian-min ZHANG
Chinese Journal of Pathology 2010;39(2):118-119
Adult
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Carcinoma, Embryonal
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drug therapy
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metabolism
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pathology
;
surgery
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Diagnosis, Differential
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Endodermal Sinus Tumor
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drug therapy
;
metabolism
;
pathology
;
surgery
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Humans
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Keratin-19
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metabolism
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Ki-1 Antigen
;
metabolism
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Male
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Orchiectomy
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methods
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Testicular Neoplasms
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drug therapy
;
metabolism
;
pathology
;
surgery
;
alpha-Fetoproteins
;
metabolism
10.Alveolar rhabdomyosarcoma of left testis: report of a case.
Chinese Journal of Pathology 2012;41(2):128-129
Adenocarcinoma
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metabolism
;
pathology
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Adult
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Desmin
;
metabolism
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Diagnosis, Differential
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Humans
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Lung Neoplasms
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secondary
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Lymphatic Metastasis
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Male
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Melanoma
;
metabolism
;
pathology
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Rhabdomyosarcoma, Alveolar
;
metabolism
;
pathology
;
surgery
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Sarcoma, Alveolar Soft Part
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metabolism
;
pathology
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Testicular Neoplasms
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metabolism
;
pathology
;
surgery
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Testis
;
metabolism
;
pathology