Struma ovarii is a monodermal and highly specialized teratoma which is composed predominantly or entirely of thyroid tissue. It is rare tumor accounting for 2.7% of ovarian mature cystic teratoma. Most of the tumors are benign. Malignant change has been reported in approximately 5% of cases. We have experienced a case of struma ovarii with brief review of the literature.
Struma Ovarii* ; Teratoma ; Thyroid Gland

Struma ovarii is a highly specilized form of mature cystic teratoma of the ovary. It is extremely rare and accounts for only 2.7% of all ovarian teratomas. When thyroid tissue constitutes more than 50% of the tumor, it is usually called a struma ovarii. We reproted a case of struma ovarii and review the literature concerning this tumor briefly.
Female ; Ovary ; Struma Ovarii* ; Teratoma ; Thyroid Gland

Struma Ovarii is a teratoma with thyroid tissue as the predominant (>50%) constituent. It is rare, representing about 2% of all teratomas, and its malignant transformation, less than 5% of struma ovarii. Presenting symptoms are not specific, therefore pre-operative diagnosis of malignant struma ovarii is difficult and most diagnosis of malignant struma ovaii is determined by post-operative histologic findings. Because of the rarity of malignant struma ovarii, there is considerable confusion concerning diagnosis and management. A postmenopausal woman presented with pelvic mass and lower abdominal pain and explo-laparotomy was performed. Then, pathologic report was identified as malignant struma ovarii. We report a case of malignant struma ovarii with brief review of literature
Abdominal Pain ; Diagnosis ; Female ; Humans ; Struma Ovarii* ; Teratoma ; Thyroid Gland

Malignant struma ovarii is a rare form of ovarian carcinoma. Sincc it is often seen as a nonspecific complex mass, its preoperative diagnosis is difficult. The MR imaging findings of benign struma ovarii have been reported, but no published account has described the malignant form. In this case, MR images depicted multiple cysts with well enhanced solid portions in the left ovary, and the typical apperarance of mature cystic teratoma in the right ovary. We describe a case of malignant struma ovarii associated with mature cystic teratoma of the contralateral ovary.
Diagnosis ; Female ; Magnetic Resonance Imaging ; Ovary* ; Struma Ovarii* ; Teratoma*

OBJECTIVE: The aim of this study was to investigate the preoperative characteristics of benign mature cystic teratoma (MCT) and struma ovarii and their risk factors associated malignancies, and determine the appropriate treatment options for these tumors. METHODS: This was a retrospective study on 248 patients who were pathologically diagnosed with ovarian MCT, struma ovarii, or malignant transformations of these tumors at Inje University Haeundae Paik Hospital from March 2010 to January 2015. Routinely evaluated results of adnexal masses before surgery were compared. RESULTS: A total of six patients (2.4%) were confirmed to have malignant tumors. Of the struma ovarii patients, two out of five patients (40%) were confirmed to have malignancy. The mean age at the diagnosis of patients with malignant transformation of teratomas was 43.0 years (range, 27 to 67 years), which was higher than that of patients with benign teratomas (36.5 years). The mean diameter of the tumor before surgery in the malignant tumor group was 11.4 cm and larger than 6.5 cm of benign group (P=0.003). The mean CA-125 level in the malignant tumor group was higher than that in the benign tumor group (P=0.01). CONCLUSION: Risk factors for malignant transformation of MCT include elevated CA-125 levels, older age, large tumor masses, and postmenopausal status.
Diagnosis ; Humans ; Retrospective Studies ; Risk Factors* ; Struma Ovarii ; Teratoma*

Struma ovarii is a monodermal teratoma composed totally or in overwhelming proportion of thyroid tissue. It is uncommon and accounts for 1% to 3% of benign teratomas of ovary. Grossly, they are encapsulated neoplasms, several centimeters in diameter and have a red, shiny, and meaty surface. Microscopically, the tumor is composed of mature thyroid tissue consisting of various sizes, lined by a single layer of columnar or flattened epithelium. The clinical behavior is benign, and simple excision is adequate treatment. We had experienced two cases of struma ovarii arising in the left ovaries. So we report above cases with brief review of literatures.
Epithelium ; Female ; Ovary ; Struma Ovarii* ; Teratoma ; Thyroid Gland

Benign or malignant tumors that arise in a benign cystic teratoma are rare. Malignant transformation in mature cystic teratoma of ovary is reported to occur in 1~3%. Several types of malignancy can occur from any of three germ-cell layers, but the most common malignancy is a squamous cell carcinoma derived from ectoderm. We experienced a papillary carcinoma arising in a struma ovarii of the complex teratoma. 74-year-old female presented with an abdominal discomfort. A pelvic ultrasonograph and computed tomography detected a 7 x 6 cm-sized and well-circumscribed cystic mass at the anterior to the uterus. The inner part of the mass was filled with cystic fluid showing low-density, however, solid portion including fat and soft tissue accompanied by calcification was identified in more than half of the entire tumor volume. The patient underwent a bilateral salpingo-oophorectomy. On histopathologic examination, the lesion was consistent with papillary carcinoma with squamoid features arising in a struma ovarii of the mature cystic teratoma. We herein report a case of the very rare papillary carcinoma arising in a struma ovarii of the complex teratoma and review the available literature.
Aged ; Carcinoma, Papillary* ; Carcinoma, Squamous Cell ; Ectoderm ; Female ; Humans ; Ovary ; Struma Ovarii* ; Teratoma* ; Tumor Burden ; Uterus

Struma ovarii, the most common monodennal teratoma of the ovary, causes diverse problems in differential diagnosis. The literature on the pathology of struma ovarii has focused principally on the problem of formulating criteria of malignancy. In contrast, unusual gross and microscopic features of struma ovarii and its resultant problems in differential diagnosis have received relatively little attention. We report an ovarian teratoma which was almost entirely cystic, causing the diagnosis of struma to be overlooked. The removed ovarian tumor showed all the features of adenomatous goiter of the thyroid gland. The lining epithelium of the cysts was frequently flattened, and the follicles in the cyst wall were few and atrophic. The patient was a 58-year-old woman who was found to have an ovarian tumor by routine monographic examination
Diagnosis ; Diagnosis, Differential ; Epithelium ; Female ; Goiter* ; Humans ; Middle Aged ; Ovary ; Pathology ; Struma Ovarii* ; Teratoma ; Thyroid Gland*

Struma ovarii consists of thyroid tissue derived from germ cells in a mature teratoma and which all or a large part is composed of thyroid tissue. Malignant transformation and clinically evident metastatic disease are very rare. The rarity of malignant struma ovarii renders evaluation of treatment modality difficult. There is evidence that these tumors behave like their thyroid counter parts, and cytoreductive surgery followed by ablation with radioactive iodine has been advocated. We have experienced a case of malignant struma ovarii. In this report, we present clinical and pathological findings of a case of malignant struma ovarii of 51-year-old patient with a review of the concerned literatures.
Germ Cells ; Humans ; Iodine ; Middle Aged ; Struma Ovarii* ; Teratoma ; Thyroid Gland

Struma ovarii is a rare tumor of the ovary pathologically resembling teratomas with thyroid components. The presenting clinical, radiological, and pathological features of patie-nts with consequent struma ovarii is diverse and does not give substantial information with regard to the nature of the ovarian tumor. Ten cases collected over a period of eight years from two institutes are presented which showed a wide diversity of clinical features, and in which the diagnosis was only made later by strict pathological criteria. The treatment for struma ovarii, and in even rarer cases, malignant struma ovarii, remains highly controvers-ial, but it is suggested that conservative treatment by tumor excision only may be sufficie-nt. Surgical treatment also greatly ameliorates any accompanying hydrothorax and ascites.
Academies and Institutes ; Ascites ; Diagnosis ; Female ; Hydrothorax ; Ovary ; Struma Ovarii* ; Teratoma ; Thyroid Gland