1.Establishment of 3D venous-fusion models and their application in meningioma operations
Tengkun YIN ; Jianjun GU ; Yinxing HUANG ; Jianbin YING ; Wei DAI ; Jingfang HONG ; Sousen WANG
Chinese Journal of Neuromedicine 2017;16(3):285-290
Objective To explore the role of 3D venous-fusion models in the resection of meningiomas.Methods The study included 19 patients with meningiomas,admitted to our hospital from March 2015 to July 2015.The preoperative and postoperative contrast enhancement MR venography (CE-MRV) data were imported into the neuronavigator system.The establishment of 3D venous-fusion models was performed;reconstruction,cropping,fusion of the intracranial venae and tumors were performed.3D venous-fusion models were used to evaluate the intracranial venous circulation,and the positions of venae and tumors were navigated in real-time.Results 3D venous-fusion models showed good results.The position relationship of tumors and their surrounding venous was perfectly assessed in operation.Nineteen patients underwent craniotomy using neuronavigator to locate venous position,and no postoperative venous complications occurred.The contrast of preoperative and postoperative 3D venous-fusion models prompted that the venous protection was in line with expectations.Conclusions The 3D venous-fusion models established by neuronavigator can accurately evaluate the relationship between cerebral venous and the tumors.These models help the operator making a better understanding of tumors and their peripheral venous imaging data from 3D perspective.It is benefit for the operator to make a more reasonable venous protect strategy.
2.Preliminary study of "overall levels of pituitary hormone" in non-functional pituitary adenoma patients
Chenyu DING ; Xuehan YI ; Tengkun YIN ; Deyong XIAO ; Zhifeng WU ; Shousen WANG
Chinese Journal of Neuromedicine 2018;17(3):227-232
Objective To study the estimated value of general pituitary hormone levels and "overall levels of pituitary hormone" in patients with pituitary adenoma.Methods Sixty-six patients presented with non-function pituitary adenomas,admitted to our hospital from January 2009 and April 2013,were chosen in our study.Pre-and post-operative hormonal levels and MR imaging data were collected.Patients were divided into two groups:macroadenoma (1 cm<diameter<3 cm) group and huge adenoma (diameter>3 cm) group,and the patients were divided into subtotal resection group (resection rate>60%) and partial resection group (resection rate<60%).Self-made scale of "overall levels of pituitary hormone" was performed to assess the remnant pituitary function.The levels for 6 kinds of pituitary hormones and "overall levels of pituitary hormone" were compared between each two groups.Results (1) The levels of 6 kinds of pituitary hormones between the macroadenoma group (n=38) and huge adenoma group (n=28) showed no significant difference before surgery (P>0.05);the per-operative "overall levels of pituitary hormone" were statistically different between the macroadenoma group (19.59±2.71) and huge adenoma group (18.07±2.00,P<0.055);there were 13 patients (34.2%) from macroadenoma group and 17 (60.7%) from huge adenoma group having one or more kinds of pituitary hormones lower than normal levels,with significant difference (P<0.05).(2) The levels of 6 kinds of pituitary hormones between subtotal resection group (n=57) and partial resection group (n=9) showed no significant difference after surgery (P>0.05);the post-operative "overall levels of pituitary hormone" in the subtotal resection group were significantly higher than those in the partial resection group (P<0.05);there were 34 patients (59.6%) from subtotal resection group and 2 (22.2%) from partial resection group having one or more kinds of pituitary hormones lower than normal levels,without significant difference (P<0.05).Conclusions The "overall levels of pituitary hormone",in which 6 kinds of pituitary hormones are seen as a whole,can assess the remnant pituitary function in pituitary adenoma patients more accurately than evaluation of the 6 kinds of pituitary hormone levels separately.
3.Subarachnoid hemorrhage secondary to cerebral venous sinus thrombosis: a report of three cases and literature review
Bingbing LI ; Jingfang HONG ; Tengkun YIN ; Songsong LU ; Haibing LIU ; Shousen WANG
Chinese Journal of Neuromedicine 2016;15(3):292-295
Objective To investigate the early clinical and imaging features,treatment strategies of subarachnoid hemorrhage secondary to cerebral venous sinus thrombosis.Methods The clinical data of 3 patients with subarachnoid hemorrhage secondary to cerebral venous sinus thrombosis,admitted to our hospital from October 2013 to March 2015,were retrospectively analyzed.One patient underwent anticoagulant therapy singly,and two underwent anticoagulation and thrombolytic therapy.Results One patient was admitted to hospital in gestation period,two patients had unknown etiology.All patients complained of headache;among them,two presented with epilepsy.Two patients with early diagnosis and treatment of anticoagnlation and thrombolysis had favorable prognosis,one patient with secondary intracranial hemorrhage had good outcome after active treatment.Conclusions For those patients with onset of non-aortogenic subarachnoid hemorrhage,we must keep an eye out for underlying cerebral venous sinus thrombosis.Anticoagulant and thrombolytic therapy are the first-line treatment.It is suggested that the appropriate dosage at the appropriate time to prevent cerebral hemorrhage from occurring is necessary.
4.Venous assessment and surgical strategy in parasagittal meningiomas
Chinese Journal of Neuromedicine 2018;17(7):738-741
Parasagittal meningioma (PSM) often causes superior sagittal sinus stenosis or occlusion,which leads to obstruction of venous circulation.The establishment of collateral circulation provides guarantee for venous reflux.Detailed and accurate preoperative evaluation and proper surgical strategies are the guarantee of achieving protection of normal venous system.The evaluation methods of imaging and its surgical values in PSM are reviewed in this article.