1.A Case of Purtecher's Retinopethy.
Hwo Sung LEE ; Young Tee CHUNG
Journal of the Korean Ophthalmological Society 1988;29(4):729-734
A 29-year-old man involved in a minor road traffic accident developed visual loss in right eye. On ophthalmological examination he had multiple exudates and edema at the posterior pole of right eye. We present the earlyangiographic findings and the late sequelar, and then suggest that total clinical picture may be purtscher's retinopathy caused by rapid of arterial and venous pressure leading to vascular damage in the nerve fiber layer.
Accidents, Traffic
;
Adult
;
Edema
;
Exudates and Transudates
;
Humans
;
Nerve Fibers
;
Venous Pressure
2.Fibrous Pseudotumor of Testicular Tunic: A Case Report.
Sung Hak KANG ; Jeong Hoon LEE ; Tee Kon HWENG ; Yong Hyun PARK
Korean Journal of Urology 1987;28(5):695-696
Fibrous pseudotumor of testicular tunic is a rare disease which has been considered to be non-neoplastic, reactive, fibrous lesions. This may be difficult to distinguish from other solid tumors arising from paratesticular tissues, and thus may be result in orchiectomy for this benign process.
Orchiectomy
;
Rare Diseases
;
Testis
3.The Effect of Levofloxacin on the Survival of Ovarian Cancer Cells with or Without Carboplatin Under Hypoxic Condition.
Sung Yun HONG ; Ju Hyun PARK ; Eun Jin KIM ; Jong Won LEE ; Suk Bong KOH ; Tee Sung LEE
Korean Journal of Obstetrics and Gynecology 2003;46(8):1517-1524
In solid tumor, there is a hypoxic region where oxygen supply is insufficient. In this study, we found that one of the quinolone antibiotics, levofloxacin, made a human ovarian cancer cells, SK-OV-3, resistant to hypoxia, even in the presence of a platinum-based anti-cancer therapeutic, carboplatin; when the cells (2 X 10(5) cells/12 well multi culture dish) were grown in no glucose medium (0 g/l) under hypoxia (1% O2), all the cells became dead after 24 hours of culture in the absence of levofloxacin and carboplatin, whereas the cells still survived, at least, until 36 hours of culture in the presence of levofloxacin (10-100 microgram/ml) alone or in combination with carboplatin. The results might have some implications in treating solid tumor; if cancer patients should be treated for infection with antibiotics, quinolone antibiotics can aggravate tumor by making cancer cells more resistant to hypoxia. This is also true even when a patient is treated with carboplatin. Therefore, the results strongly suggest that we should be careful in choosing antibiotics when they are used for cancer patients. In this regard, our work could be a new guideline in choosing antibiotics when antibiotics are applied for treating cancer patients.
Anoxia
;
Anti-Bacterial Agents
;
Carboplatin*
;
Cell Survival
;
Glucose
;
Humans
;
Levofloxacin*
;
Ovarian Neoplasms*
;
Oxygen
4.Malignant Struma Ovarii: two cases report and literature review.
Eun Jin KIM ; Chi Dong HAN ; Chang Kyu HUH ; Ghil Suk YOON ; Suk Bong KOH ; Tee Sung LEE
Korean Journal of Obstetrics and Gynecology 2001;44(12):2352-2356
Struma ovarii consists of thyroid tissue which is derived from germ cells in a mature teratoma. Five percent of struma ovarii are malignant, and of these only five percent metastasize. The rarity of this disease has resulted in difficulty in agreeing on treatment regimens and in limited imaging and monitoring difficulties encountered in their management. We have experienced two cases of malignant struma ovarii with brief review of the literature.
Germ Cells
;
Neoplasms, Germ Cell and Embryonal
;
Struma Ovarii*
;
Teratoma
;
Thyroid Gland
5.The Relationship between the Expression of Cytokeratins, Ki-67, and the Infection of Human Papillomavirus 16, 18 Type in the Carcinogenic Progression of the Uterine Cervical Epithelium.
Eui Sok SOL ; Chi Dong HAN ; Tee Sung LEE ; Suk Bong KOH
Korean Journal of Obstetrics and Gynecology 2003;46(6):1159-1167
OBJECTIVE: To evaluate the relationship between the expression of cytokeratins, Ki-67 and the infection of human papillomavirus 16, 18 type in the carcinogenic progrssion of the uterine cervical epithelium. METHODS: Investigation the expression patterns of CKs and Ki-67 monoclonal antibody, and compared them with the incidence of HPV infection in 120 patients including 30 cases of normal cervical epithelium, 30 cases of LSIL, 30 cases of HSIL and 30 cases of SCC, to possible relationship between them. RESULTS: The expression of CK 14, and Ki-67 increased as the cervical lesions progressed from normal to SILs and SCC. In contrast, CK 13 is decreased as the cervical lesions progressed from normal to SILs and SCC. Statistical analysis revealed significant corelations between the CK 14 and spinal layer, between CK 13 and basal layer, between Ki-67 and all layers. HPV was detected in 16.7% of normal cervical tissue, 50.0% of LSIL, 70.0% of HSIL, 80.0% of SCC with PCR technique. The labelling indices of Ki-67 were significantly higher in HSIL than in normal cervical tissue and LSIL. The labelling indices were also higher in groups with positive reactions to CK 14, 13, and HPV than in groups with negative reactions to them. CONCLUSION: It was postulated that examination of patterns of immunoreactivity of CK 14, 13, and Ki- 67 could be a useful and convenient tool to explain the trasition from normal cervical epithelium to SCC via LSIL and HSIL and thereby predict the differentiation potential of the studies for lesions.
Epithelium*
;
Human papillomavirus 16*
;
Humans*
;
Incidence
;
Keratins*
;
Polymerase Chain Reaction
6.Hepatocellular Carcinoma Metastatic to the Ovary: one case report and review literature.
Ju Hyun PARK ; Chi Dong HAN ; Chang Kyu HUH ; Jeong Ja PARK ; Ho Gak KIM ; Kyung Jae JUNG ; Suk Bong KOH ; Tee Sung LEE
Korean Journal of Obstetrics and Gynecology 2001;44(10):1900-1904
Metastatic hepatocellular carcinoma of the ovary is an extremely rare ovarian tumors and may cause a diagnostic problem. This tumor was first described by Ooartman and Elliot in 1983. The differential diagnosis in cases of hepatocellular carcinoma metastatic to the ovary is with primary and metastatic hepatoid tumors of the ovary and diverse other tumors of the ovary composed of oxyphil cells, which may be primary or metastatic. We have experienced one case of metastatic hepatocellular carcinoma of the ovary with brief review of the literature.
Carcinoma, Hepatocellular*
;
Diagnosis, Differential
;
Female
;
Ovary*
;
Oxyphil Cells