1.99mTc-HMPAO labelled WBC scan in experimental abscess by labelling autologous leukocu\ytes with in-house-synthesized HMPAO.
Dong Soo LEE ; Hyung Sik SHIN ; Curie AHN ; June Key CHUNG ; Myung Chul LEE ; Kang Won CHOI ; Chang Soon KOH ; Jae Min JUNG ; Eun Ju CHUNG
Korean Journal of Nuclear Medicine 1991;25(2):252-258
No abstract available.
Abscess*
;
Technetium Tc 99m Exametazime*
2.Radiopharmaceutical factors in the prepartion of 99mTc-HMPAO imagesof the brain.
Mi Kyoung YEOM ; Sang Eun KIM ; Dong Soo LEE ; June Key CHUNG ; Myung Chul LEE ; Chang Soon KOH
Korean Journal of Nuclear Medicine 1991;25(1):117-121
No abstract available.
Brain*
;
Technetium Tc 99m Exametazime*
3.Radiopharmaceutical factors in the prepartion of 99mTc-HMPAO imagesof the brain.
Mi Kyoung YEOM ; Sang Eun KIM ; Dong Soo LEE ; June Key CHUNG ; Myung Chul LEE ; Chang Soon KOH
Korean Journal of Nuclear Medicine 1991;25(1):117-121
No abstract available.
Brain*
;
Technetium Tc 99m Exametazime*
4.99mTc-HMPAO WBC scan findings in pulmonary mucormycosis.
Chang Woon CHOI ; Sang Eun KIM ; Dong Soo LEE ; June Key CHUNG ; Myung Chul LEE ; Chang Soon KOH
Korean Journal of Nuclear Medicine 1991;25(2):296-297
No abstract available.
Mucormycosis*
;
Technetium Tc 99m Exametazime*
5.Different Uptake of Tc-99m ECD and Tc-99m HMPAO in the Normal Brains - Analysis by Statistical Parametric Mapping.
Euy Neyng KIM ; Yong An JUNG ; Hyung Sun SOHN ; Sung Hoon KIM ; Ie Ryung YOO ; Soo Kyo CHUNG
Korean Journal of Nuclear Medicine 2002;36(4):244-254
No abstract available.
Brain*
;
Technetium Tc 99m Exametazime*
6.Optimization of Correction Factor for Linearization with Tc-99m HM PAO and Tc-99m ECD Brain SPECT.
Ihn Ho CHO ; Kohei HAYASHIDA ; Kyu Chang WON ; Hyoung Woo LEE ; Hiroshi WATABE ; Norihiko KUME ; Chikao UYAMA
Yeungnam University Journal of Medicine 1999;16(2):237-243
No abstract available.
Brain*
;
Technetium Tc 99m Exametazime
;
Tomography, Emission-Computed, Single-Photon*
7.99mTc-HMPAO regional cerebral blood flow SPECT in cerebral infarctsand ischemia.
Chi Moon HWANG ; Hye Yeon HAN ; Hee Sang KIM ; Kyung Hoi AHN
Journal of the Korean Academy of Rehabilitation Medicine 1992;16(3):265-271
No abstract available.
Ischemia*
;
Technetium Tc 99m Exametazime*
;
Tomography, Emission-Computed, Single-Photon*
8.Thalamic syndrome with related cortical hypoperfusion on 99mTc-HMPAO brain SPECT.
Eun Kyung KIM ; Tae Sub CHUNG ; Jung Ho SUH ; Dong Ik KIM ; Jong Doo LEE ; Chang Yoon PARK ; Yong Kook HONG ; Myung Sik LEE
Korean Journal of Nuclear Medicine 1992;26(1):33-39
No abstract available.
Brain*
;
Technetium Tc 99m Exametazime*
;
Thalamic Diseases*
;
Tomography, Emission-Computed, Single-Photon*
9.Quantification of Cerebrovascular Reserve Using Tc-99m HMPAO Brain SPECT and Lassen's Algorithm.
Dong Soo LEE ; June Key CHUNG ; Myung Chul LEE ; Seok Ki KIM ; Kyeong Min KIM ; Jae Sung LEE ; Keon Wook KANG ; Jeong Seok YEO
Korean Journal of Nuclear Medicine 2000;34(4):322-335
PURPOSE: For quantitative estimation of cerebrovascular reserve (CVR), we estimated the cerebral blood flow (CBF) using Lassen's nonlinearity correction algorithm and Tc-99m HMPAO brain SPECT images acquired with consecutive acquisition protocol. Using the values of CBF in basal and acetazolamide (ACZ) stress states, CBF increase was calculated. MATERALS AND METHODS: In 9 normal subjects (age: 72+/-4 years), brain SPECT was performed at basal and ACZ stress states consecutively after injection of 555 MBq and 1,110 MBq of Tc-99m HMPAO, respectively. Cerebellum was automatically extracted as reference region on basal SPECT image using threshold method. Assuming basal CBF of cerebellum as 55 ml/100 g/min, CBF was calculated for every pixel at basal states using Lassen's algorithm. Cerebellar blood flow at stress was estimated comparing counts of cerebellum at rest and ACZ stress and Lassen's algorithm. CBF of every pixel at ACZ stress state was calculated using Lassen's algorithm and ACZ cerebellar count. CVR was calculated by subtracting basal CBF from ACZ stress CBF for every pixel. The percent CVR was calculated by dividing CVR by basal CBF. The CBF and percentage CVR parametric images were generated. RESULTS: The CBF and percentage CVR parametric images were obtained successfully in all the subjects. Global mean CBF were 49.6+/-5.5 ml/100g/min and 64.4+/-10.2 ml/100g/min at basal and ACZ stress states, respectively. The increase of CBF at ACZ stress state was 14.7+/-9.6 ml/100g/min. The global mean percent CVR was 30.7% and was higher than the 13.8% calculated using count images. CONCLUSION: The blood flow at basal and ACZ stress states and cerebrovascular reserve were estimated using basal/ACZ Tc-99m-HMPAO SPECT images and Lassen's algorithm. Using these values, parametric images for blood flow and cerebrovascular reserve were generated.
Acetazolamide
;
Brain*
;
Cerebellum
;
Technetium Tc 99m Exametazime*
;
Tomography, Emission-Computed, Single-Photon*
10.Diagnosis of Cerebrovascular Disease Using 99mTc-HMPAO SPECT.
Do Heum YOON ; Seung Kon HUH ; Kyu Chang LEE ; Do Yun LEE ; Tae Sub CHUNG
Journal of Korean Neurosurgical Society 1988;17(5):1029-1034
A new radiopharmaceutical, technetium-99m hexamethylpropyleneamine oxime(99mTc-HMPAO), has been reported to cross the blood-brain-barrier and to distribute in brain in proportion to regional blood flow. Measurement of cerebral blood flow with single photon emixxion computed tomography(SPECT) was performed using 99mTc-HMPO in 46 patients and clinical analysis was done. Decreased regional cerebral perfusion was observed in 41 cases. Moreover eight cases of them who had normal X-ray C-T scan revealed positive finding on SPECT. We porpose that 99mTc-HMPAO SPECT seems to be a useful diagnostic method for evaluation of ischemic cerebral lesions.
Brain
;
Diagnosis*
;
Humans
;
Perfusion
;
Regional Blood Flow
;
Technetium Tc 99m Exametazime*
;
Tomography, Emission-Computed, Single-Photon*
Result Analysis
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