1.A study on prevalence rate and related risk factors for house wive's low back pain.
Korean Journal of Epidemiology 1993;15(2):196-211
No abstract available.
Low Back Pain*
;
Prevalence*
;
Risk Factors*
2.Immunohistochemical characteristics of Monocyte chemotactic protein-1 in the Endometrium of women with Endometriosis.
Dong Ho KIM ; Tea Chul KIM ; Gyu Hyun KANG ; Min HUR ; Eun Sub PARK ; Dae Won KIM ; Doo Suk CHOI ; Jung Goo KIM
Korean Journal of Obstetrics and Gynecology 2000;43(12):2140-2145
No abstract available.
Chemokine CCL2*
;
Endometriosis*
;
Endometrium*
;
Female
;
Humans
;
Monocytes*
3.Clinical Study on Cesarean Hysterectomy.
Sung Hoon CHOI ; Min Jung KIM ; Woo Chul JUNG ; Won Suk CHOI ; Tea Young KIM ; Moung Do KIL ; Kyoung Don BAIK
Korean Journal of Obstetrics and Gynecology 2002;45(7):1159-1163
OBJECTIVE: This article was to review 10 years experience of cesarean hysterectomy at our hospital. To review risk factors, management & outcome of emergency peripartum hysterectomy performed in last 10 years at our hospital. MATERIAL & METHODS: The outcome of 33 cases of cesarean hysterectomy performed at St. Benedict hospital during 10 years from Jan. 1990 to Dec. 1999 was discussed & evaluated. RESULTS: During this time, there was 16014 deliveries, of which 5640 were cesarean section and 25 were cesarean hysterectomies, an incidence of 0.44%, and of which 10374 were vaginal deliveries 8 were. Cesarian hysterectomies are incidence of 0.08%. The age of patients varies from 18 to 42. The higher the age and the parity of patients, the higher incidence of cesarean hysterectomy was noted. The most common indication of cesarean hysterectomy was placental abnormal presentation [placenta accreta (30.3%), placenta previa (27.2%)], uterine atony (33.3%), uterine myoma with pregnancy (6.0%) and Uterine ruture (3.0%). The complication were febrile morbidity, disseminated intravascular coagulopathy and urinary tract injury. There was one maternal death. CONCLUSION: Postoperative complication still remain the causes of maternal morbidity. There careful prenatal care momentary judgement of right operation time, fresh whole blood transfusion and reduction of operation time must be conjunction with maternal life saving. Cesarean delivery, prior cesarean delivery placenta accreta and uterine atony were identified as risk factors for emergency peripartum hysterectomy and abnormal presentation was the primary cause of cesarean hysterectomy. Still, cesarean hysterectomy remains a potentially life saving procedure with which every obstetrician must be familiar.
Blood Transfusion
;
Cesarean Section
;
Emergencies
;
Female
;
Humans
;
Hysterectomy*
;
Incidence
;
Leiomyoma
;
Maternal Death
;
Parity
;
Peripartum Period
;
Placenta Accreta
;
Placenta Previa
;
Postoperative Complications
;
Pregnancy
;
Prenatal Care
;
Risk Factors
;
Urinary Tract
;
Uterine Inertia
4.Anticancer effects of D-pinitol in human oral squamous carcinoma cells
Hyun-Chul SHIN ; Tea-Hyun BANG ; Hae-Mi KANG ; Bong-Soo PARK ; In-Ryoung KIM
International Journal of Oral Biology 2020;45(4):152-161
D-pinitol is an analog of 3-methoxy-D-chiro-inositol found in beans and plants. D-pinitol has anti-inflammatory, antidiabetic, and anticancer effects. Additionally, D-pinitol induces apoptosis and inhibits metastasis in breast and prostate cancers. However, to date, no study has investigated the anticancer effects of D-pinitol in oral cancer. Therefore, in this study, whether the anticancer effects of D-pinitol induce apoptosis, inhibit the epithelialto-mesenchymal transition (EMT), and arrest cell cycle was investigated in squamous epithelial cells. D-pinitol decreased the survival and cell proliferation rates of CAL-27 and Ca9-22 oral squamous carcinoma cells in a concentration- and time-dependent manner. Evidence of apoptosis, including nuclear condensation, poly (ADP-ribose) polymerase, and caspase-3 fragmentation, was also observed. D-pinitol inhibited the migration and invasion of both cell lines. In terms of EMT-related proteins, E-cadherin was increased, whereas N-cadherin, Snail, and Slug weredecreased. D-pinitol also decreased the expression of cyclin D1, a protein involved in the cell cycle, but increased the expression of p21, a cyclin-dependent kinase inhibitor. Hence, D-pinitol induces apoptosis and cell cycle arrest in CAL-27 and Ca9-22 cells, demonstrating an anticancer effect by decreasing the EMT.
5.Implications of Mechanical Endovascular Thrombectomy for Acute Basilar and Posterior Cerebral Artery Occlusion.
Hyun Nyung LEE ; Bum Tea KIM ; Soo Bin IM ; Sun Chul HWANG ; Je Hoon JEONG ; Moon Young CHUNG ; Jong Hyun PARK ; Dong Seong SHIN
Journal of Cerebrovascular and Endovascular Neurosurgery 2018;20(3):168-175
OBJECTIVE: Protocols for posterior circulation ischemic stroke have not been established by randomized clinical trials. Mechanical endovascular thrombectomy (MET) devices are evolving, and many of these devices already developed or in development are suitable for posterior circulation MET. MATERIALS AND METHODS: We investigated the medical records of patients who underwent MET for posterior circulation ischemic stroke from January 2012 to August 2016. Fifteen patients were included. MET was performed in patients with or without injected intravenous tissue plasminogen activator. MET was considered in patients with a National Institute of Health Stroke Scale score of 4 or more, older than 18 years, with definite occlusion of the basilar artery or posterior cerebral artery (PCA), and who arrived at the hospital within 24 hours from onset. RESULTS: The direct catheter aspiration technique was used in five cases, and the stent retrieval technique was used in seven cases. The stent retrieval technique with the direct aspiration technique was used in three cases. Recanalization failed in two cases. Basilar occlusion without PCA involvement is the only effective factor of successful recanalization (p = 0.03). Successful recanalization (p = 0.005) and the presence of a posterior communicating artery (p = 0.005) affected the good outcome at discharge. CONCLUSION: An early diagnosis and active MET may improve the patient outcome. MET may help recanalization and good flow restoration and the potential for a good outcome.
Arteries
;
Basilar Artery
;
Catheters
;
Early Diagnosis
;
Humans
;
Medical Records
;
Passive Cutaneous Anaphylaxis
;
Posterior Cerebral Artery*
;
Stents
;
Stroke
;
Thrombectomy*
;
Tissue Plasminogen Activator
6.In vitro development of canine somatic cell nuclear transfer embryos in different culture media.
Dong Hoon KIM ; Jin Gu NO ; Mi Kyung CHOI ; Dong Hyeon YEOM ; Dong Kyo KIM ; Byoung Chul YANG ; Jae Gyu YOO ; Min Kyu KIM ; Hong Tea KIM
Journal of Veterinary Science 2015;16(2):233-235
The objective of the present study was to investigate the effects of three different culture media on the development of canine somatic cell nuclear transfer (SCNT) embryos. Canine cloned embryos were cultured in modified synthetic oviductal fluid (mSOF), porcine zygote medium-3 (PZM-3), or G1/G2 sequential media. Our results showed that the G1/G2 media yielded significantly higher morula and blastocyst development in canine SCNT embryos (26.1% and 7.8%, respectively) compared to PZM-3 (8.5% and 0%) or mSOF (2.3% and 0%) media. In conclusion, this study suggests that blastocysts can be produced more efficiently using G1/G2 media to culture canine SCNT embryos.
Animals
;
Blastocyst/cytology
;
Cloning, Organism/*veterinary
;
Culture Media/metabolism
;
Dogs/*embryology
;
Embryo Culture Techniques/*veterinary
;
*Embryonic Development
;
Nuclear Transfer Techniques/*veterinary
7.Antioxidative and Antidiarrheal Effects of Persimmon Extracts.
Dongsun PARK ; Sun Hee LEE ; Dae Kwon BAE ; Young Jin CHO ; Tea Kyun KIM ; Yun Hui YANG ; Goeun YANG ; Sang Chul KWON ; Do Ik LEE ; Sung Soo JOO ; Yun Bae KIM
Laboratory Animal Research 2010;26(4):407-413
Since oxidative stresses are involved in gastroenteritis and diarrhea, we investigated antioxidative and antidiarrheal activities of persimmon flesh extract (PFE) and persimmon calyx extract (PCE) in vitro and in vivo, respectively. PCE significantly scavenged 1,1-diphenyl-2-picrylhydrazyl hydrate and 2,2'-azinobis (3-ethylbenzthiazoline-6-sulfonic acid) from 500 microg/mL, although PFE was ineffective. In addition, PFE and PCE exhibited strong nitric oxide-scavenging effects from 1 microg/mL, in which PCE was superior to ascorbic acid (50 microM). Furthermore, PFE and PCE significantly inhibited FeCl3-induced lipid peroxidation as well as Cu2+/H2O2-induced protein oxidation from 10 microg/mL. In vivo charcoal-propulsion assay, in contrast to a negligible effect of PFE, treatment with PCE (160-500 mg/kg) markedly inhibited intestinal motility. The results indicate that extracts of persimmon, especially PCE, possess antioxidative, antiinflammatory and antidiarrheal activities. Therefore, it is suggested that persimmon extracts could be used for the relief of gastroenteritis and diarrhea.
Ascorbic Acid
;
Biphenyl Compounds
;
Diarrhea
;
Diospyros
;
Gastroenteritis
;
Gastrointestinal Motility
;
Lipid Peroxidation
;
Oxidative Stress
;
Picrates
8.Biliary Complications after Adult Liver Transplantation.
Sang Soo LEE ; Kyu Taek LEE ; Sun Young LEE ; Tea Wook KANG ; Won MOON ; Ji Young HWANG ; Min Kyu YU ; Jong Kyun LEE ; Seung Woon PAIK ; Jae Won JOH ; Suk Koo LEE ; Sang Heum KIM ; Jong Chul RHEE
Korean Journal of Gastrointestinal Endoscopy 2006;32(2):94-100
BACKGROUND/AIMS: Recently, living donor liver transplantation (LDLT) has been frequently performed in Korea because of the limited availability of a cadaveric donor (CD). We evaluated the clinical features of patients with biliary complications after liver transplantation and we compared the incidence of biliary complications according to the type of donor and the anastomotic type of the biliary tract. METHODS: Between May 1996 and July 2004, 300 patients (CDLT 102/LDLT 198) underwent liver transplantation at Samsung Medical Center. The patients who experienced biliary complications during the follow-up period were enrolled to the study and we retrospectively reviewed their cases. RESULTS: Sixty-seven cases (23%) of biliary complications were noticed in 53 patients (18%). The complications consisted of 20 cases (7%) of bile leakage, 38 cases (13%) of biliary strictures, 7 cases (2%) of biliary stones, and 2 cases (1%) of biliary stenosis due to other cause. There was no significant difference on the incidence of complications between CDLT (15/102; 14.7%) and LDLT (38/198; 19.2%) (p=0.42). In addition, there was no significant difference between choledocho-choledochostomy (43/237; 18.1%) and hepatico-jejunostomy (10/ 63; 15.9%)(p=0.85) CONCLUSIONS: The incidence rate of biliary complication after liver transplantation was 23%, and there was no difference according to the type of donor and the anastomotic type of biliary tract.
Adult*
;
Bile
;
Biliary Tract
;
Cadaver
;
Constriction, Pathologic
;
Follow-Up Studies
;
Humans
;
Incidence
;
Korea
;
Liver Transplantation*
;
Liver*
;
Living Donors
;
Retrospective Studies
;
Tissue Donors