Objective To explore the causes and solutions of rehospitalization of the high-risk neonates. Methods The data collection form was designed based on the literature reviewing and the discussion of the nursing quality management team. Results The samples were retrospectively collected from January 2015 to October 2015. There were 106 cases readmitted among the 3012 discharged cases with the ratio of 3.52%. The average interval of readmission were (4.92±4.0) days, most of the cases were readmitted in 7 days after the first discharge with a ratio of 83.95%, the ratio of readmission within 3 days was 38.68%and that was 45.28%for the readmission within 4~7days. For the Preterm infants, the ratio of readmission within 3 days was 21.69%which was higher than that of the full term (16.98%), there was no statistically significant difference between the two groups(chi-square= 1.45, P>1.45). While the ratio of readmission within 7 days for premature infants was 49.06%(52/106), which was higher than that of full term infants [34.91%(37/106)], and there was statistically significant difference between the two groups(chi-square = 5.45, P<0.05). Jaundice was found to be the major reason for unplanned rehospitalization with the ratio of 50.94%. When compared the incidence of readmission contributed by improper feeding between the low birth weigh and normal birth weight infants, there was nostatistical significance (chi-square = 3.58, P>3.58). But when compared between preterm infants and full term, a higher ratio was found in preterm infants (16.04%), and there was statistically significant difference (chi-square = 5.83, P< 0.05). Conclusion One week after discharge was the peak time of readmission.Jaundice was the main factor of readmission. Premature babies were more likely to have readmission due to feeding problems.

The present paper is aimed to study the processes of stress reaction and their judgment bases in rat induced by 35 GHz millimeter wave quantitatively. The relative change in the average energy of each EEG frequency band decomposed by wavelet analysis was calculated for extracting the stress indicator for the purpose. The rat would experience quiet period, guarding period, deadlock period and prostrating period in sequence. The judgment bases of different stress periods in rat induced by millimeter wave were obtained by analyzing the skin temperature, skin injury and changes of blood biochemical indexes during each stress period. The stress period changed from quiet period to guarding period when the skin temperature of irradiated area reached the thermal pain threshold. It was from guarding period to deadlock period when the skin had gotten serious injury. Then the rat reaction sensitivity decreased, and injury of its visceral organs occurred. The rat got to prostrating period when the sustained irradiation caused the rat's visceral organs to get more serious injury. The further sustained irradiation finally induced death of the rat.
Animals ; Dose-Response Relationship, Radiation ; Electroencephalography ; radiation effects ; Electromagnetic Radiation ; Male ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Skin ; radiation effects ; Skin Temperature ; radiation effects ; Stress, Physiological ; radiation effects

It is very important to extract electroencephalogram (EEG) rhythm in clinical diagnoses. Digital filter and wavelet transform are used to extract the rhythm from a piece of EEG at the sampling rate of 2 kHz. The Daubechies order 4 wavelet (db4) was used to decompose the EEG at 8 levels. According to the filter characteristic of wavelet decomposition, the reconstructions of aS, d8, d7, d6 and d5 component are nearly corresponding to the rhythms of delta, theta, alpha, gamma separately. The 6 order ellipse infinite impulse response (IIR) filter is also used to decompose the EEG. As the quality factor of wavelet decomposition filter is constant, the wavelet transform obtains better extracted rhythm than the digital filter. Furthermore, the wavelet transform method can be used to extract the low frequency rhythm from wide frequency band.
Algorithms ; Artifacts ; Brain ; physiology ; Electroencephalography ; methods ; Humans ; Signal Processing, Computer-Assisted

Objective : To investigate the effects of resveratrol(Res) on fibroblast-like synoviocytes(FLS) in patients with rheumatoid arthritis(RA), and to explore the possible mechanism of Res inhibiting the release of inflammatory factors from FLS. Methods : FLS from RA patients were culturedin vitroand treated with different concentrations of Res(0, 20, 40, 80, 160, 320 μmol/L). The viability of FLS cells was detected by CCK-8 assay after 12 and 24 h. The contents of inflammatory factor interleukin-6(IL-6) and tumor necrosis factor-α(TNF-α) in cell supernatant were detected by ELISA. The expression levels of cyclic guanosine monophosphate-adenosine monophosphate synthase(cGAS) and stimulator of interferon gene(STING) were measured by Western blot; After lentivirus infection with FLS caused the cells to overexpress cGAS, the cells were divided into Control group(blank control), cGAS group(cGAS overexpression), Res+cGAS group(Res 160 μmol/L+cGAS overexpression) and Res group(Res 160 μmol/L). The expression level of STING protein in cells of each group was determined by Western blot, the viability of FLS cells in each group was detected by CCK-8, and the contents of inflammatory factor IL-6 and TNF-α in the supernatant of cells of each group were detected by ELISA method. Results : The results of CCK-8 experiment showed that under 40, 80, 160 μmol/L Res treatment, FLS viability decreased significantly after 24 h compared with blank control group(P<0.01). ELISA results showed that the contents of IL-6 and TNF-α in cell supernatant were also significantly decreased after treatment with Res of 40, 80 and 160 μmol/L(P<0.01). Meanwhile, Western blot results showed that Res could significantly decrease the protein expression levels of STING and cGAS in FLS cells after treatment of 40, 80 and 160 μmol/L(P<0.05,P<0.01). Compared with the Control group, the expression level of STING protein in FLS increased after overexpression of cGAS(P<0.05); compared with the Res group, the content of inflammatory factors in the supernatant of FLS and the expression level of STING protein in FLS significantly increased after overexpression of cGAS(P<0.01,P<0.05). Conclusion The appropriate concentration of Res can inhibit the release of inflammatory cytokines in FLS cells, which may be related to the blocking of cGAS-STING signaling pathway.