Objective To investigate the subjective well-being and social relational quality of patients with pulmonary tuberculosis, and to analyze the relationship between them,so as to provide a new perspective to improve the quality of life of patients with pulmonary tuberculosis.Methods Totals of 346 patients with pulmonary tuberculosis were surveyed by the Social Relational Quality Scale and the Memorial University of Newfoundland Scale of Happiness.The pearson correlation analysis and multiple linear regression analysis were used to explore the relationship between subjective well-being and social relational quality of patients with pulmonary tuberculosis.Results The total score of subjective well-being in the patients with pulmonary tuberculosis was (21.70 ±6.65), and 31.21% of them was in the low level, 56.65% of them was in the medium level, 12.14%of them was in the high level.The total score of positive factor was (14.33 ±4.31), which was significantly lower than (16.63 ±4.68) of the negative factor (t=-6.724,P<0.01).The total score of social relational quality was (44.93 ±5.21).The score of subjective well-being was positively correlated with the score family cohesion, family commitment, friendship and social relational quality ( r =0.453,0.436,0.408,0.432, respectively;P<0.05).Multiple linear regression analysis showed that the family cohesion, family commitment, friendship were the predictors of subjective well-being of patients with pulmonary tuberculosis (P<0.05).Conclusions The subjective well-being and social relational quality were in the low level, and the social relational quality was the influencing factor of subjective well-being in patients with pulmonary tuberculosis, so we should improve the subjective well-being by improving the social relational quality.