1.Research progress of Autologous Fat Grafting for Scar Treatment
Journal of Medical Postgraduates 2016;29(9):982-986
The scar tissue, resulting from aberrant process of wound healing , can bring about cosmetic deformeties and func-tional limitation, even the displacement of tissues and organs .The widely use of autologous fat graft in regenerative medicine offers a relatively new option for scar treatment .Lipofilling has improved symptoms and appearance of scars in several studies .The application , therapeutic effect and mechanism research of autologous fat graft for scar treatment are summarized in this paper .
2.Problems encountered while managing a case of severe ovarian hyperstimulation syndrome
Yap-Garcia Ma. Isidora Margarit ; Tan Delfin A.
Philippine Journal of Reproductive Endocrinology and Infertility 2010;7():42-48
This is the case of a 26 year-old nulligravida with Polycystic Ovary Syndrome who developed severe Ovarian Hyperstimulation Syndrome (OHSS) during ovulation induction for Intrauterine Insemination (IUI). Three problems were encountered during treatment. The first was whether to convert a planned ovulation induction and IUI, that resulted in multiple follicular development, to an in vitro Fertilization - Intracytoplasmic Sperm Injection cycle. The second problem was determining what strategies are relevant in preventing OHSS in a woman at high risk for developing severe hyperstimulation. The third problem was why, when and how to employ abdominal paracentesis in the management of severe OHSS. Though the patient's course was turbulent, management was successful. She is now awaiting embryo transfer and, ultimately, motherhood.
Human
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Female
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Adult
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OVARIAN HYPERSTIMULATION SYNDROME
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POLYCYSTIC OVARY SYNDROME
3.Detection for optical properties of biological tissue based on time-correlated single-photon counting technology
Dongli TAN ; Zheng MA ; Feng GAO
Chinese Medical Equipment Journal 1989;0(04):-
Some issues of time-correlated single-photon counting technology for detection for optical properties of biological tissue are discussed,including its basic principle,components and conventional methods applying the technology.
4.The research of 64-slice spiral CT in assessing the mild and severe stenosis of coronary artery
Chunpeng MA ; Qingsheng WANG ; Qiang TAN
Chinese Journal of Postgraduates of Medicine 2008;31(16):22-24
Objective To evaluate the accuracy of 64-slice spiral CT(64 SCT)in assessing the mild and severe stenosis of coronary artery.Methods A total of 72 patients suspected to suffer from coronary artery disease underwent orderly both 64 SCT and selective coronary angiography(SCAG).Volume rendering (VR),multi-planar reconstruction(MPR),maximum intensity projection(MIP)and transverse section wasused to analyze the 64 SCT data.The results were compared with those of SCAG to investigate the accuracy of the 64 SCT in assessing the≥50% stenosis of coronary artery.Results In the 720 SCAG segments of 72 patients.684 of them could be evaluated by 64 SCT.The evaluated rate Was 95.0%.Compared with SCAG,the sensitivity,specificity,positive predictive value,negative predictive value and accuracy rate was 67.4%,92.9%,69.5%,92.3% and 88.0% respectively.Conclusion The accuracy of 64 SCT in assessing mild and severe stenosis is relatively high and it can be used for screening patients with suspected coronary artery diseases as a non-invasive method.
5.Mechanism about bile duct strictures after liver transplantation
Yuefeng MA ; Weili FU ; Wenxiang TAN
International Journal of Surgery 2009;36(4):266-269
Biliary complications are a serious problem in patients after liver transplantation, which often results in graft loss, the causes of bile duct stricture are complex. This paper reviewed the mechanism of bile duet stricture after liver transplantation. This complication maybe related with various factors such as liver arterial thrombosis, loss of blood supply of bile duct, warm iscbemia/preservation injury, chronic ductopenic rejection, cytomegalovirus infection, ABO incompatibility, and recurrence of primary sclerosing cholangitis.
6.Formation mechanisms, regulating factors and clinical significance of vasculogenic mimicry
Jie LI ; Xiaojie MA ; Bangxian TAN
Journal of International Oncology 2010;37(8):576-578
Vasculogenic mimicry (VM) can promote tumor growth, invasion, and metastasis. The formation of VM is regulated by various proteins including epithelial cell kinase, phosphoinositide-3 kinase, and hypoxia-inducible factor 1. Local microenvironment also plays an important role in regulating VM formation.
7.Relationship between factor-1α and epithelial mesenchymal transformation
Chun CAO ; Xiaojie MA ; Bangxian TAN
Journal of International Oncology 2014;41(6):415-418
Hypoxia inducible factor (HIF-1α) is a hypoxia response regulator,which is highly expressed in malignant tumors.Researches have shown that HIF-1α plays an important role in epithelial mesenchymal transformation.It can regulate epithelial mesenchymal transition through a series of signal pathways and mechanisms at many levels,to participate in the invasion and metastasis of tumors.To explore the mechanism of HIF-lα controlling epithelial mesenchymal transformation has important significance for the development of new,effective tumor treatment methods.
8.Prognostic and survival analysis of primary liver cancer after hepatectomy
Xiaojie MA ; Jie LI ; Bangxian TAN
Cancer Research and Clinic 2013;25(9):588-590
Objective To explore the factors related to the prognosis and survival duration of primary liver cancer patients after hepatectomy.Methods The data of primary liver cancer patientswho were treated by surgical resection were analyzed retrospectively.Kaplain-Meier method was used to evaluate survival rates.Log-rank test and Cox regression analysis were used to screen out related clinical phathology factors.Results The median survival time was eighteen months.Univarivate analysis showed that liver function Child-Pugh classification,cirrhosis,tumor size,HBV infection,AFP,portal vein tumor thrombus significantly correlated with survival rates (P < 0.05).Multivariate analysis showed that liver function Child-Pugh classification,tumor size,AFP and portal vein tumor thrombus were the independent prognostic factors of primary liver cancer (P < 0.05).Conclusion Many factors are related to the prognosis of primary liver cancer after operation.Liver function Child-Pugh classification,tumor size,AFP and portal vein tumor thrombus affect prognostic independently.
9.A novel amorphous calcium phosphate drug-eluting stent:its biocompatibility after implantation into mini-swine coronary artery
Chinese Journal of Tissue Engineering Research 2016;20(16):2354-2359
BACKGROUND:As previously reported, poly-L-lactic acid stents have been mostly used as coronary artery stents, but this stent has a lack of early support force and produces some acidic products that wil induce local vascular inflammatory reactions.
OBJECTIVE:To explore the biocompatibility of a novel amorphous calcium phosphate drug-eluting stent, after implantation into mini-swine coronary artery.
METHODS:Twenty mini-swine were randomly equivalently divided into observation group and control group. The right femoral arteries of animals were separated layer by layer and the new type of biodegradable stent and poly-L-lactic acid stent were implanted, respectively.
RESULTS AND CONCLUSION:The vessel lumes in the two groups were smooth and unobstructed showed by coronary artery angiography immediately after implantation. At 4 weeks after implantation, the coronary angiography showed the patency of vessel lumens with no stent thrombosis and stenosis in both two groups. The C-reactive protein levels in the two groups had no significant differences before and 4 weeks after stent implantation. At 4 weeks after implantation, the number of lymphocytes and inflammatory score in the observation group were significantly higher than those in the control group, but the neointimal area and percentage of stenosis area had no significant difference between the two groups. These results indicate that the novel amorphous calcium phosphate drug-eluting stent after implantation into mini-swine coronary artery has good biocompatibility.
10.Application of colposcope in cervical cancer screening in Yunnan ethnic minority areas
Hongmei AN ; Lu TAN ; Lisha MA ; Jihong DENG
Chinese Journal of Postgraduates of Medicine 2014;37(36):1-3
Objective To investigate the application of colposcope in cervical cancer screening in Yunnan ethnic minority areas.Methods The questionnaire survey was conducted on 641 women,and the data of the colposcopy and biopsy were reviewed retrospectively.The colposcopy and pathological diagnosis results were compared.Results The minority women thought colposcopy more acceptable was 78.64% (383/487).The colposcopy found suspected low-grade cervical lesions were 377 cases,high-grade cervical lesions were 245 cases,cervical condyloma were 15 cases,cervical cancer were 4 cases.The pathological results:278 cases of cervical intraepithelial neoplasia (CIN) Ⅰ,174 cases of CIN Ⅱ,55 cases of CIN Ⅲ,15 cases of cervical condyloma,4 cases of cervical cancer.The consistent rate of colposcopy and pathological examination was 68.17% (257/377) in low-grade lesions,89.39% (219/245) in high-grade lesions,cervical cancer and cervical condyloma was entirely consistent.Conclusions The colposcopy is more easily accepted in Yunnan ethnic minority areas,which could be a preliminary diagnosis of cervical lesions,cervical condyloma and cervical cancer.It has an important clinical application value in diagnosis of cervical diseases.