1.Critical Discourse Analysis in Doctor-patient Discourse in Chinese Medical Clinic
Chinese Medical Ethics 2015;(1):8-12
Critical Discourse Analysis ( CDA) attempts to uncover the inequality in social reality and the way language presents power and ideology through the analysis of language features. Systemic functional linguistics ( SFL) focuses on the dialectical relationship between language and society and has been considered an important approach and theoretical basis to CDA. Doctors in Chinese medical clinic follow the Four Diagnostic Methods, within which the inquiry diagnosis strongly shows the fact that doctor and patient clash over the ideology and strug-gle for the power via language. The study carries out CDA on doctor-patient discourse in Chinese medical clinic within the theoretical framework of SFL from four aspects including nominalization, classification, transitivity and mood, which verifies that the language is the product of asymmetric power between doctor and patient. It is hoped that the paper would provide insight into CDA on doctor-patient discourse and would be of theoretical meaning.
2.Environmental Pollution by Quinolines Antibiotics from Human and Animal Excreta
Journal of Environment and Health 2007;0(12):-
Quinolines antibiotics present stable chemical properties ,higher excretion of prototype drug. Most of quinolines antibiotics used by human and animals show original and various biological activity forms in the excrement,which is important to ecological environment and human health. The data indicate that the present clinical treatment is facing frequent occurrence and higher rates of quinolines antibiotics-resistance, which is related to environmental pollution by quinolines antibiotics. So far as little research is focused on the management of the excrement from human and animals using quinolines antibiotics, and the control, management of the residues of excrement are very important for reducing the risk of antibiotic-resistance in human.
3.THE EFFECT OF TRILOBINE HYDROCHLORIDE ON BLOOD PRESSURE IN CATS
Academic Journal of Second Military Medical University 1981;0(03):-
Twenty-two casts of either sex were anesthesized with urethan, and their respiration, carotid arterial pressure (BP) and ECG were recorded.6 of the 22 cats were given trilobine iv of different doses of 1.25, 2.5,5.0, 10.0, 20.0mg/kg. It was found that all the dosage levels of trilobine produced a fall in blood pressure ranging from 30 to 60 mmHg. The extent of the hypo-tensive effect seems to be dose-dependent.The other 16 cats were divided into 3 groups and used to analyse the mechanism of the hypotensive action of trilobine.The first group (6 cats) was treated with the cholinergic M-receptor blokage-atropine, adrenergic ?-receptor blokage-propranol, ganglionic biokage-C6, and section of bilateral vagus nerve.The second group (5 cats) was treated with the adrenergic ?-receptor agonist-noradrenaline.The third group (5 cats) was treated with the histaminergic H1, H2-receptor blokage-diphenhydramine, cimetidine.The experimental results indicated that all of the above treatments had no influence on the hypotensive effect of trilobine, suggesting that the mechanism of hypotensive effect of trilobine may not relate to the cholinergic M, N receptor,the adrenergic ?, ? receptor, the histaminergic H1,H2 receptor and the vagus nerves.It is possible that a direct action on blood vessel may be involved.
4.Clinical investigation of irbesartan in treatment of chronic congestive heart failure
Chinese Journal of Clinical Pharmacology and Therapeutics 2000;0(02):-
AIM: To evaluate the therapeutic effect and safety of irbesartan in treatment of chronic congestive heart failure. METHODS: 80 patients with chronic congestive heart failure were randomizedly divided into the irbesartan group and the routine group, 40 cases in every group. The routine group was treated with nomal treatment digtoxin ethacrynicum and dilation vasocular, and the irbesartan group was treated with irbesartan 75- 300 mg one time daily based on the nomal treatment. The course of treatment was 12 weeks. RESULTS: Irbesartan could improve symptom and heart function clearly (P
5.Observation of Schizophrenic patients' Compliance managed by divisional service
Journal of Xi'an Jiaotong University(Medical Sciences) 2003;0(06):-
Objective To observe the effect of divisional service on the compliance of patients with schizophrenia.Methods Altogether 160 patients with schizophrenia were randomly divided into the study group and control group,each with 80 patients.Prospective control trial was applied to observe the change of compliance and clinical symptoms before and after one-year treatment.Results The compliance of patients in the study group,who received divisional service,was significantly higher than that in the control group(P
6.The relationship between children attention-deficit/hyperactivity disorder and blood lead and blood microelements levels
Journal of Chongqing Medical University 2003;0(05):-
Objective:To investigate the relationship between blood lead and blood microelements levels and attention-deficit/ hyperactivity disorder.Methods:To compare the children of ADHD and control groups,levels of blood lead were analysised by anodic stripping voltammetry,and blood microelement Levels were detected by atomic absorption spectrophotometry.Results: Blood lead levels were significantly higher in ADHD than that in control group (P
7.The changes of t-PA and PAI activities in plasma and hemorrheology in patients with retinal vein occlusion treated by panax no-toginseng saponins
Ophthalmology in China 1993;0(04):-
The changes of tissue type plasminogen activator (t-PA) and plasminogen activator inhibitor (PAI) activities in plasma and hemorrheology were observed in 36 patients with retinal vein occlusion (RVO) before and after the treatment of panax notoginseng saponins (PNS). The results showed that the activity of t-PA was increased remarkably and activity of PAI was decreased obviously after one month with PNS intravenous injection in comparison with that before the treatment (Before the treatment, they were 1.65 + 0.54IU/inl and 8.61 + 1.19AU/ml, and after treatment 2. 26?0.49lU/ml and 7. 56?1.16AU/ml, respectively, p
8.Effect of adenosine on myocardial expression of TNF-?, IL-6 mRNA in rats with pneumonia
Chinese Journal of Pathophysiology 2000;0(10):-
AIM: To observe the expression of TNF-?, I L-6 mRNA in injured myocardium caused by infectious pneumonia and the effects of exogenous adenosine.METHODS: Fifty rats were divided into five experimental groups at random. The model of pneumonia was replicated by the inj ection of staphylococcus aureus into the windpipe of rats. Adenosine-treated ra ts (A,B and C group) received daily injection of adenosine at different dosages (50, 100 and 150 ?g?kg -1 ?min -1 for 90 min) for 3 days. All rat s were killed on the fifth day. Pathological examination of myocardium were don e and TNF-?, IL-6 mRNA expression were detected by reverse transcription poly m erase chain reaction (RT-PCR). RESULTS: (1) Significant increa se in TNF-?, IL-6 mRNA expression was observed in myocardium of pneumonic rats compared with control group ( P0 05). IL-6 mRNA expression in adenosine-treated C group was lower than that in adenosine-treated B group ( P
9.The relation of muscle protein degradation and 26S proteasome
Chinese Journal of Pathophysiology 1999;0(09):-
The ubiquitin-dependent 20s/26s proteasome system is the capital pathway of exo-lysosome proteolysis within eukaryotic cell. Under conditions of denervation, starvation, glucocorticoid, infection, tumor, burn and so on, the proteasome system was stimulated to degrade protein, which results in muscle lose fast. Glucocorticoid, insulin, thyroid hormone,TNF? and IL-1? play important roles in the regulation of muscle protein degradation and the proteasome system. Inhibition or activation of the proteasome system was approved to be a novel means of treatment with cachexia and negative nitrogen balance. [
10.Study on the Bioequiavailability of Zolmitriptan Tablets in Human Body
China Pharmacy 2005;0(16):-
OBJECTIVE:To study the bioavailability of the domestic and the imported zolmitriptan tablets in human body.METHODS:The plasma concentration of zolmitriptan in24healthy male volunteers were determined by HPLC-FI after o?rally administered with single dose of5mg zolmitriptan tablets by randomized crossover way,the pharmacokinetics parameters and the relative bioavailability of which were calculated.RESULTS:The plasma concentration-time curves of the oral zolmitriptan tablets fitted one-compartment open model of linear dynamics,the main parameters of domestic tablets and im?ported tablets were described as follows,C max (8.273?3.379)ng/ml and(7.756?2.623)ng/ml,t max (2.341?1.169)h and(2.644?1.121)h,AUC 0~t (47.95?15.75)(ng?h)/ml and(46.27?13.71)(ng?h)/ml,the relative bioavailability of do?mestic zolmitriptan tablets and the imported tablets was(106.72?32.03)%.CONCLUSION:The domestic and the imported zomitriptan tablets is bioequivalent.