1.A Retrospective Review Of Tinea Capitis Infection
Malaysian Journal of Dermatology 2014;32(-):31-34
Background: Tinea capitis (TC), a fungal infection of the scalp, hair follicles and hair shafts, is
common among the paediatric population especially under tropical conditions1. The etiological factors
vary between different regions of the world. Clinical presentation of tinea capitis varies widely from
non-inflammatory to severe, painful inflammatory lesions.
Aim: To look into the clinical manifestations, causative agents and the treatment pattern for tinea
capitis in Penang Hospital.
Methods: A retrospective study of all patients who were treated clinically for tinea capitis in Penang
Hospital from January 2011 to June 2013.
Results: There were a total of thirty nine patients treated for tinea capitis during this period. Tinea
capitis was found to be most common in the 7-12 year age group (44%) with a male to female ratio
of 2:1. Non-inflammatory type (54%) was more common then the inflammatory type. Twenty seven
of them (69%) had positive fungal culture of their pluck hair roots. The most common dermatophyte
detected was Microsporum canis (92%) followed by Trichophyton rubrum (4%) and Trichophyton
metagraphyte (4%). Thirty-one (80%) of them were treated with griseofulvin at a dose of 10-15mg /
kg /day. The rest were treated with itraconazole, terbinafine or fluconazole. All of them responded well
to the treatment. In this cohort only one patient, has a second episode of infection a year later. He is a
child who was concomitantly undergoing chemotherapy for acute lymphoblastic leukaemia.
Conclusion: Tinea capitis is predominantly an infection of pre-adolescent children and M. canis was
the most common dermatophyte isolated.
2.Kirschner Wire Migration to the Cervical Spine: AComplication of Clavicular Fixation in a Child
Malaysian Orthopaedic Journal 2007;1(1):45-46
We report a case of a broken K wire migrating to the cervical spine from the right clavicle in a 9 year old child. The initial diagnosis, fracture of the clavicle with an acromioclavicular joint dislocation, was treated by open reduction and K wiring. One K wire broke and migrated to the neck, posterolateral to the C6 vertebra. The K wire was removed percutaneously under image intensification. Acromioclavicular joint dislocation in children is rare since the distal clavicle does not ossify until the age o
3.Churg Strauss Syndrome in a 40 year old woman
Malaysian Journal of Dermatology 2010;25(-):21-24
Cutaneous vasculitis is a common manifestation of
many systemic diseases. In the setting of asthma,
eosinophilia and multiple disparate signs and
symptoms, more serious cause of vasculitis like
Churg-Strauss syndrome (CSS) should always be
considered.
4.Microperforate Hymen Presenting as Tubo-Ovarian Abscess in Adulthood
Journal of Surgical Academia 2018;8(2):27-30
Microperforate hymen is a rare vaginal anomaly that is usually reported in childhood due to recurrent urogenital infections. Unlike imperforate hymen where the presenting complaints are classical due to complete vaginal obstruction, the less profound and varied presentation of microperforate hymen may go unnoticed. We report a case of a 39-year-old, with a background history of amenorrhea, who presented with acute abdomen suggestive of tubo-ovarian abscess, and was finally diagnosed to have microperforate hymen. She underwent hymenectomy to correct the anomaly. To our knowledge, this is the oldest age of presentation of a congenital form of microperforate hymen. A high index of suspicion and early detection of microperforate hymen and properly timed intervention is essential to prevent acute symptoms and long term detrimental sequalae to women’s reproductive and psychosexual health
congenital anomalies
;
imperforate hymen
;
microperforate hymen
;
surgical correction
;
tubo-ovarian abscess
5.Bedside Continuous Irrigation and Drainage as an Interim Local Treatment for Septic Arthritis of the Knee in the Medically Unstable Patient: A Case Report
Khoo SS ; Loi KW ; Tan KT ; Suhaeb AR ; Simmrat S
Malaysian Orthopaedic Journal 2015;9(2):57-59
Septic arthritis is a surgical emergency. Prompt diagnosis
and immediate treatment reduce the destruction of articular
cartilage and give better outcome. We describe a simple,
minimally invasive closed tube irrigation system for the
initial treatment of septic arthritis of the knee in a patient
with complex medical problems who was unfit to undergo
surgery.
Arthritis, Infectious
6.Adherence To Acne Medication And Its Relation To Acne Severity And Quality Of Life
Tan CL ; Yang SS ; Toh MPH ; Aw DC
Malaysian Journal of Dermatology 2015;34(-):11-16
Background: Acne vulgaris is a chronic condition which commonly affects adolescents and exerts a
psychological burden on its sufferers. Non-adherence to acne treatment is believed to be a major factor
contributing to treatment failure. In this study, we characterize the profile of a non-adherent Asian
acne patient, and evaluate the relationship between treatment adherence and acne severity and quality
of life.
Methods: A total of 53 acne patients were recruited from the Dermatology outpatient clinic of National
University Hospital, Singapore, and followed up over a 3 month period in this prospective observational
study. The Elaboration d’un outil d’evaluation de l’observance (ECOB) adherence assessment tool
was used to assess adherence to acne treatment, and acne severity was evaluated using the US Food
and Drug Administration Center 5-point Acne Severity Score (ASS).
Results: Of the 53 study participants, 29 (54.7%) were non-adherent to acne treatment. There was
no significant difference in gender, educational level or acne severity at time of presentation between
adherent and non-adherent patients. Adherent patients had a significantly larger improvement in acne
severity scores compared to non-adherent patients (change in ASS: -1.33 ± 0.64 vs -0.76 ± 0.83, p =
0.008), but this did not translate to a significant improvement in quality of life.
Conclusion: Adherence to acne treatment was not associated with demographic characteristics or
acne severity. Factors contributing to adherence to acne treatment are complex and multi-faceted, and
individualized motivation and education of each patient may be the method of choice in encouraging
treatment adherence.
7.Carbimazole-induced aplastic anaemia - a case report
Vijay AP ; Lim SS ; Tan ATB ; Rokiah P ; Chan SP
Journal of University of Malaya Medical Centre 2009;12(2):92-95
Antithyroid drugs have been used for more than 50 years for the management of hyperthyroidism.
Most patients tolerate treatment well, but some may develop rare life threatening side effects such
as agranulocytosis and aplastic anaemia. Clinical experience with the latter condition is extremely
limited. We report on a case of carbimazole-induced aplastic anaemia caused by hypocellular bone
marrow and associated plasmacytosis in a thyrotoxic patient chronically treated with carbimazole.
This resolved after substitution with propylthiouracil. The clinical course was complicated by
neutropaenic septicaemia and atrial fibrillation.
Thyrotoxicosis
8.Simultaneous Bilateral Proximal Humeri Anterior Fracture Dislocations in a Patient with 1st Onset Seizure. A Case Report and Review of the Literature
Kelvin G Tan ; Sathappan SS ; Ganesan N R
Malaysian Orthopaedic Journal 2011;5(2):37-40
Bilateral anterior fracture-dislocations of humeral neck in a patient with seizure are extremely rare. We describe a rare case of a 33 -year-old Chinese gentleman who presented post seizure secondary to subdural gliosis, sequelae from a previous subdural haematoma. Following physical examination and radiographic assessment, including a Computed Tomography scan (CT scan), Rarely fracturedislocation of bilateral proximal humeri were diagnosed; similar fracture patterns were noted. Open reduction and internal fixation with PHILOS proximal humeral locking plate allowed early shoulder rehabilitation.
9.Adequacy of Care in patient with Psoriasis (ADECAP) Study
Tan WC ; Chan LC ; Ong KP ; Tan SS ; Kweh MW ; Jeffrey L ; Kalaikumar N
Malaysian Journal of Dermatology 2011;26(-):12-17
Introduction: Psoriasis is a chronic recurrent inflammatory skin disease and poses a lifelong
burden. Psoriasis is now considered a systemic inflammatory disease. Increasing epidemiological
studies have established the role of psoriasis as an independent risk factor in the development of
metabolic syndrome and its components. This has led to changes in standard of care
recommendations for patients with psoriasis. We conducted a clinical audit on “adequacy of care in
patient with psoriasis”.
Objective: To examine current trend of practice in the treatment of adults with psoriasis in
Dermatology clinic (tertiary referral centre), Penang Hospital. This study also aims to determine the
adequacy of care in psoriasis patients in general, and those on systemic agents in specific.
Method: A retrospective study examined all adult psoriasis patients who visited Dermatology
Clinic, Penang Hospital within 1st July - 31st July 2009. Only those who have been on follow-up for
at least 1 year were included in the study. Demographic characteristics, disease burden and details
of psoriasis management were documented and analysed. Standards were derived from
recommendations of the British Association of Dermatologists (BAD) and American Academy of
Dermatology (AAD).
Results: Of the 112 patients, 67 were males (59.8%). The mean age of patients was 48.8 years. Fifty
(44.6%) were Chinese, 35 Malay (31.3%), 26 Indians (23.2%) and 1 foreigner (0.9%). The mean
frequency of clinic visit was 8.2. Forty-seven patients required systemic agents to achieve better
disease control. Eighty-three (74.1%) patients were offered “Psoriasis Education Programme”.
Percentage of patients who had their severity scoring done by using the DLQI, BSA & Pain score
were 73.2%, 90.2% and 85.7% respectively. Only less than 50% of our patients were offered
“Metabolic Syndrome Risk Factors Screening”. Of those on systemic agents, only 87.2% and 46.8%
of patients, had their baseline and follow up blood investigations done respectively.
Conclusion: The care of psoriasis patients in Dermatology Clinic, Penang Hospital is still not
adequate. Particular areas of concern include blood monitoring for those on systemic agents and
screening for metabolic syndrome risk factors.
Remedial measures: Guidelines have been designed to create awareness and to educate doctors and
patients on psoriasis and its association with metabolic syndrome. This includes a flow chart / tables
to facilitate monitoring and screening of patients. Patients will be given pamphlets on the general
knowledge on psoriasis, treatments and the risk of co-morbidities.
10.A Case of Recalcitrant Actinomycosis Unresponsive to Antibiotic Therapy.
Mingjuan TAN ; Joyce Ss LEE ; Jiun Yit PAN
Annals of the Academy of Medicine, Singapore 2016;45(10):475-476
Actinomycosis
;
complications
;
drug therapy
;
pathology
;
Aged, 80 and over
;
Amoxicillin-Potassium Clavulanate Combination
;
therapeutic use
;
Anti-Bacterial Agents
;
therapeutic use
;
Cephalexin
;
therapeutic use
;
Ciprofloxacin
;
therapeutic use
;
Clindamycin
;
therapeutic use
;
Coinfection
;
drug therapy
;
Drug Resistance, Bacterial
;
Escherichia coli Infections
;
complications
;
drug therapy
;
Humans
;
Male
;
Pseudomonas Infections
;
complications
;
drug therapy
;
Skin Diseases, Bacterial
;
complications
;
drug therapy
;
pathology
;
Staphylococcal Skin Infections
;
complications
;
drug therapy
;
Thigh
;
Trimethoprim, Sulfamethoxazole Drug Combination
;
therapeutic use